cs.MAFeb 25, 2026

Pancake: Hierarchical Memory System for Multi-Agent LLM Serving

Authors: Zhengding Hu, Zaifeng Pan, Prabhleen Kaur, Vibha Murthy, Zhongkai Yu, Yue Guan, Zhen Wang, Steven Swanson, 

Organizations: Computer Science and Engineering, University of California, San Diego

Abstract

In this work, we identify and address the core challenges of agentic memory management in LLM serving, where large-scale storage, frequent updates, and multiple coexisting agents jointly introduce complex and high-cost approximate nearest neighbor (ANN) searching problems. We present Pancake, a multi-tier agentic memory system that unifies three key techniques: (i) multi-level index caching for single agents, (ii) coordinated index management across multiple agents, and (iii) collaborative GPU-CPU acceleration. Pancake exposes easy-to-use interface that can be integrated into memory-based agents like Mem-GPT, and is compatible with agentic frameworks such as LangChain and LlamaIndex. Experiments on realistic agent workloads show that Pancake substantially outperforms existing frameworks, achieving more than 4.29x end-to-end throughput improvement.

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