eess.IVMar 27, 2026

FINDER: Zero-Shot Field-Integrated Network for Distortion-free EPI Reconstruction in Diffusion MRI

Authors: Namgyu Han, Seong Dae Yun, Chaeeun Lim, Sunghyun Seok, Sunju Kim, Yoonhwan Kim, Yohan Jun, Tae Hyung Kim, +2 more

Organizations: Department of Artificial Intelligence and Robotics, Sejong University, Seoul 05006, South Korea · Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Jülich, Jülich, Germany · Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA · Harvard Medical School, Boston, MA 02115, USA · Department of Computer Engineering, Hongik University, Seoul 04066, South Korea

Abstract

Echo-planar imaging (EPI) remains the cornerstone of diffusion MRI, but it is prone to severe geometric distortions due to its rapid sampling scheme that renders the sequence highly sensitive to B0B_{0} field inhomogeneities. While deep learning has helped improve MRI reconstruction, integrating robust geometric distortion correction into a self-supervised framework remains an unmet need. To address this, we present FINDER (Field-Integrated Network for Distortion-free EPI Reconstruction), a novel zero-shot, scan-specific framework that reformulates reconstruction as a joint optimization of the underlying image and the B0B_{0} field map. Specifically, we employ a physics-guided unrolled network that integrates dual-domain denoisers and virtual coil extensions to enforce robust data consistency. This is coupled with an Implicit Neural Representation (INR) conditioned on spatial coordinates and latent image features to model the off-resonance field as a continuous, differentiable function. Employing an alternating minimization strategy, FINDER synergistically updates the reconstruction network and the field map, effectively disentangling susceptibility-induced geometric distortions from anatomical structures. Experimental results demonstrate that FINDER achieves superior geometric fidelity and image quality compared to state-of-the-art baselines, offering a robust solution for high-quality diffusion imaging.

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