Removing Motion Artifact in MRI by Using a Perceptual Loss Driven Deep Learning Framework

Motion artifacts in magnetic resonance imaging (MRI) degrade diagnostic reliability. Existing deep learning methods are typically contrast-specific and fail to generalize across diverse modalities and artifact severities. We propose a unified framework combining parameter-informed contrast disentanglement with severity-aware adaptive correction. ScanCLIP, pretrained on over 30,000 MRI text-image pairs, derives contrast embeddings from acquisition parameters to disentangle contrast style from anatomical content, yielding contrast-free features. A Vision Transformer then estimates motion severity and routes features through a Mixture-of-Experts network, enabling targeted artifact correction. A dual-pathway decoder reconstructs both the clean image and residual artifact map, enforcing image-space consistency. On IXI and HCP benchmarks, our method improves PSNR by 0.75 dB and SSIM by up to 0.0279 over state-of-the-art approaches, with larger gains at higher artifact severities. It further demonstrates robust zero-shot generalization on real-world clinical data acquired with unseen scanning parameters, where existing methods either fail to remove artifacts or introduce additional distortions.

Patient motion remains a source of image degradation in brain MRI, leading to signal loss, blurring, and geometric distortion that compromise quantitative analysis. Existing deep learning methods for motion correction typically rely on paired clean-corrupted data or k-space acquisitions, which are rarely available in clinical settings. We propose SSRL-MAR, a motion artifact-aware unpaired representation learning framework for motion artifact reduction that requires neither paired training data nor explicit motion labels. SSRL-MAR employed a three-stage training strategy: (1) contrastive learning on 3D patches to extract motion representations by contrasting clean and synthetically corrupted images, (2) a motion artifact-aware synthesis network to generate motion artifacts from clean scans, and (3) a motion artifact-aware generator to restore clean volumes using the learned degrader for self-supervised supervision. On in-silico dataset, SSRL-MAR achieved PSNR 23.81dB, SSIM 91.55%, and NMSE 0.79%. On in-vivo MR-ART dataset, the pretrained model reduced motion distortion, and unsupervised domain adaptation further improved anatomical fidelity. Against a source-only supervised model trained on the same simulated pairs, SSRL-MAR improved PSNR by up to 2.0 dB on MR-ART after unsupervised domain adaptation, and remained within 0.25-0.47 dB of an oracle supervised model that requires real paired data unavailable in practice. At the milder motion level, volumetric error in structures such as the corpus callosum and ventricular system decreased by more than 50%, confirming improved neuroanatomical consistency. These results indicate that SSRL-MAR provides a robust and scalable image-domain solution for 3D brain MRI motion correction, enabling reliable structural quantification in large-scale neuroimaging studies without requiring prospectively acquired pairs or acquisition-specific calibration.

Automated quality assessment of structural brain MRI is an important prerequisite for reliable neuroimaging analysis, but yet remains challenging due to motion artifacts and poor generalization across acquisition sites. Existing approaches based on image quality metrics (IQMs) or deep learning either requires extensive preprocessing, which incurs high computational cost, or poor generalization to unseen data. In this work, we propose a lightweight and interpretable framework for detecting motion related artifacts in T1 weighted brain MRI by extending the Discriminative Histogram of Gradient Magnitude (DHoGM) to a three dimensional space. The proposed method integrates complementary slice-level (2D) and volume-level (3D) DHoGM features through a parallel decision strategy, capturing both localized and global motion-induced degradation. Volumetric analysis is performed using overlapping 3D cuboids to achieve comprehensive spatial coverage while maintaining computational efficiency. A simple threshold-based classifier and a low parameter multilayer perceptron are used, which results in a model with only 209 trainable parameters. Our method was evaluated on the MR-ART and ABIDE datasets under both seen-site and unseen-site conditions. Experimental results demonstrate strong performance, achieving up to 94.34% accuracy the in domain evaluation and 89% accuracy on unseen sites, while almost completely avoiding false acceptance of poor-quality scans. Ablation studies confirms the complementary benefits of combining 2D and 3D features. Overall, the proposed approach offers an effective, efficient, and robust solution for automated MRI quality check, with strong potential for integration into large scale clinical and research workflows.