Agentic Microphysics: A Manifesto for Generative AI Safety

As large language models are increasingly deployed as interacting agents in high-stakes decisions, the AI safety community assumes that safety properties of individual models will compose into safe multi-agent behavior. This position paper argues that this assumption is fundamentally mistaken. In agentic AI, safety is determined by interaction topology, not model weights. When agents deliberate sequentially or aggregate via parallel voting with a judge, the structure of information flow and decision coupling dominates outcomes. Evidence across model families and scales reveals three persistent topology-driven pathologies: ordering instability, where system behavior depends primarily on agent sequence; information cascades, where early judgments propagate regardless of correctness; and functional collapse, where systems satisfy fairness metrics while abandoning meaningful risk discrimination. Contrary to intuition, scaling to more capable models strengthens these effects by increasing consensus formation and reducing the challenge of initial decisions. These failure modes are invisible to model-centric evaluation and alignment procedures. We argue that agentic AI must be treated as a dynamical system rather than a collection of aligned components. Interaction topology must become a primary target of safety evaluation and regulation, with systems required to demonstrate robustness across architectural variations before deployment.

Multi-agent systems composed of large generative models are rapidly moving from laboratory prototypes to real-world deployments, where they jointly plan, negotiate, and allocate shared resources to solve complex tasks. While such systems promise unprecedented scalability and autonomy, their collective interaction also gives rise to failure modes that cannot be reduced to individual agents. Understanding these emergent risks is therefore critical. Here, we present a pioneer study of such emergent multi-agent risk in workflows that involve competition over shared resources (e.g., computing resources or market share), sequential handoff collaboration (where downstream agents see only predecessor outputs), collective decision aggregation, and others. Across these settings, we observe that such group behaviors arise frequently across repeated trials and a wide range of interaction conditions, rather than as rare or pathological cases. In particular, phenomena such as collusion-like coordination and conformity emerge with non-trivial frequency under realistic resource constraints, communication protocols, and role assignments, mirroring well-known pathologies in human societies despite no explicit instruction. Moreover, these risks cannot be prevented by existing agent-level safeguards alone. These findings expose the dark side of intelligent multi-agent systems: a social intelligence risk where agent collectives, despite no instruction to do so, spontaneously reproduce familiar failure patterns from human societies.

We present key challenges and future research directions in the security and privacy of agentic AI, based on a horizon-scanning exercise that brought together thirty leading international experts from academia, industry, and government to engage in focused discussions and collaborative exercises on the emerging risks associated with the growing agency of AI.