Evaluating LLMs as Human Surrogates in Controlled Experiments

LLMs are increasingly used as human surrogates, often on the premise that richer persona data could make them substitutes or exploratory tools for specific individuals. We test this premise across four datasets covering more than 400,000 participants and more than 6,000 survey items and experimental outcomes. LLMs perform well at the aggregate level: their average responses closely align with average human responses to the same items. But this success largely reflects predicting each item's average human response. Once each item's human mean is removed, LLM predictions explain only 3.05% of the remaining respondent-specific variation, far below the 53.6% human test-retest benchmark. Richer personas, model variants, and fine-tuning do not close this gap. In variance analyses, once item means are removed, the reliable remaining signal is person-by-item. It captures how a respondent departs from the mean on a particular item and is about 8.9x larger than the stable person effect. Persona data encode the respondent, but not this item-specific deviation. LLM responses also compress human response distributions, using less spread, fewer response categories, and distorted distributional shapes. We call this pattern item-mean surrogacy. Current LLM surrogates can approximate item averages, but not the distributions or respondent-specific deviations needed to replace individual humans. We propose four empirical tests for LLM-based human-surrogate claims.

A growing literature uses large language models (LLMs) as synthetic participants to generate cost-effective and nearly instantaneous responses in social science experiments. However, there is limited guidance on when such simulations support valid inference about human behavior. We contrast two strategies for obtaining valid estimates of causal effects and clarify the assumptions under which each is suitable for exploratory versus confirmatory research. Heuristic approaches seek to establish that simulated and observed human behavior are interchangeable through prompt engineering, model fine-tuning, and other repair strategies designed to reduce LLM-induced inaccuracies. While useful for many exploratory tasks, heuristic approaches lack the formal statistical guarantees typically required for confirmatory research. In contrast, statistical calibration combines auxiliary human data with statistical adjustments to account for discrepancies between observed and simulated responses. Under explicit assumptions, statistical calibration preserves validity and provides more precise estimates of causal effects at lower cost than experiments that rely solely on human participants. Yet the potential of both approaches depends on how well LLMs approximate the relevant populations. We consider what opportunities are overlooked when researchers focus myopically on substituting LLMs for human participants in a study.

Large language models (LLMs) are increasingly used to simulate human behavior in business, economics, and the social sciences, offering a low-cost complement to laboratory experiments, field studies, and surveys. This paper evaluates how well LLMs replicate human behavior in operations management. Using nine published behavioral-operations experiments, we assess LLM performance along two dimensions: whether LLM-generated data reproduce the original hypothesis-test outcomes, and whether their full response distributions align with human data, measured by Wasserstein distance. We find that LLMs often replicate hypothesis-level effects, suggesting that they can capture salient decision biases and behavioral regularities. However, their response distributions frequently diverge from human data, even for strong proprietary models, with dispersion mismatch playing an important role. We also examine two lightweight mitigation strategies: chain-of-thought prompting and hyperparameter tuning. Both can reduce distributional misalignment, and appropriate tuning can sometimes allow smaller or open-source models to match or outperform larger proprietary systems.