What Makes Synthetic Data Effective in Image Segmentation

Diffusion models are primarily trained for image synthesis, yet their denoising trajectories encode rich, spatially aligned visual priors. In this paper, we demonstrate that these priors can be utilized for text-conditioned semantic and open-vocabulary segmentation, and this approach can be generalized to various downstream tasks to make a general-purpose diffusion segmentation framework. Concretely, we introduce DiGSeg (Diffusion Models as a Generalist Segmentation Learner), which repurposes a pretrained diffusion model into a unified segmentation framework. Our approach encodes the input image and ground-truth mask into the latent space and concatenates them as conditioning signals for the diffusion U-Net. A parallel CLIP-aligned text pathway injects language features across multiple scales, enabling the model to align textual queries with evolving visual representations. This design transforms an off-the-shelf diffusion backbone into a universal interface that produces structured segmentation masks conditioned on both appearance and arbitrary text prompts. Extensive experiments demonstrate state-of-the-art performance on standard semantic segmentation benchmarks, as well as strong open-vocabulary generalization and cross-domain transfer to medical, remote sensing, and agricultural scenarios-without domain-specific architectural customization. These results indicate that modern diffusion backbones can serve as generalist segmentation learners rather than pure generators, narrowing the gap between visual generation and visual understanding.

Semantic segmentation models struggle with data sparsity and rare or visually diverse regions, e.g., dense regions or small objects in aerial or autonomous mobility data. While synthetic augmentation is an appealing solution, directly generating new labeled data risks misalignment of labels and generated pixels. Existing solutions to this problem often rely on external models, or employ coarse heuristics such as indiscriminately augmenting all foreground objects or entire backgrounds, which wastes capacity on uninformative pixels. To address this, we propose an uncertainty-guided synthetic context augmentation strategy that strictly preserves label validity and efficiently maximizes pixel informativeness per synthetic sample - no external guardrails required. Using a baseline segmenter's predictive entropy, we identify uncertain semantic regions and inpaint only the complementary visual context. When fine-tuning the segmenter on this synthetic data, we compute the loss only over the original pixels, excluding inpainted regions. This focuses learning on the unmodified, uncertain regions while presenting them in novel contexts. We demonstrate substantial mIoU gains on Cityscapes, UAVID, and BDD100K with the largest gains on rare and difficult classes such as buses, trains, or (from the aerial perspective) cars. Our results demonstrate that uncertainty-guided context augmentation is a highly effective lever to improve segmentation performance on complex datasets, with code provided at https://github.com/XITASO/Preserve-the-Hard-Regenerate-the-Rest.

Several disruptive research directions have recently emerged in computer vision, including foundation models achieving previously unseen zero-shot performance in scene understanding, even interactively, and generative models that synthesize extremely realistic images. The latter have also been shown to be highly effective in scene understanding tasks thanks to their rich priors. However, for promptable segmentation, foundation models struggle with accurately segmenting an object's region, leading to false positives and over-segmentation. Notably, early attempts that leverage generative priors use prompts only during post-processing, yielding suboptimal segments because the process is agnostic to the user input. In this paper, we target these limitations with Prompt2Seg, a spatial conditioning framework for diffusion-based segmentation. Prompt2Seg augments a frozen diffusion segmentation model with a conditioning branch. Our approach takes spatial prompts, represented as 2D Gaussians or confidence maps, as explicit input signals, training the model to respond directly to user intent. Fine-tuned on a deliberately constrained set of object categories drawn from Hypersim and Virtual KITTI 2, Prompt2Seg generalizes zero-shot to a wide range of unseen object types and visual domains. We evaluate on seven datasets ranging from standard benchmarks to more challenging domains, including paintings, egocentric views, and X-ray data. Furthermore, we demonstrate that Prompt2Seg consistently outperforms the underlying diffusion segmentation backbone across all benchmarks. Our results suggest that the rich priors encoded in generative pretraining, combined with principled spatial conditioning, offer a compelling path toward broadly generalizing interactive segmentation without large-scale mask supervision.