Organizations: Washington University in St. Louis, St. Louis, MO, USA · Texas A&M University, College Station, TX, USA · Johns Hopkins University, Baltimore, MD, USA
Abstract
Indirect prompt injection (IPI) is a major security threat to LLM-powered agents. Thus, a growing body of work have proposed a variety of defensive approaches against IPI. These can be grouped into three broad categories: 1) prompt-based (using prompting as a way to prevent agents from following malicious instructions), 2) detection-based (identifying and filtering malicious instructions), and 3) system-level (using systems insights, such as control and data isolation, for defense). However, commonly used benchmarks for evaluating defense, such as AgentDojo, are \emph{inherently static}, generating a fixed distribution of IPI attacks. Consequently, static benchmarks do not usefully evaluate defense robustness to adaptive threats. We address this issue by developing AutoDojo, an adaptive extension of AgentDojo that optimizes IPI against a given defense. Using AutoDojo against state-of-the-art IPI defenses across three task suites and five target models, we make two key observations. First, many defenses offer only limited protection: a cheap, black-box adaptive attack using a frontier LLM to iteratively optimize the injection raises attack success rate (ASR) well above the level achieved by static injections against nearly all evaluated defenses. Against a filter that reduces static ASR to 0%, AutoDojo recovers 28% overall and 64% on action-open tasks. Second, for prompt-level and filter-based defenses, ASR is substantially higher on \emph{action-open} tasks -- where the user's request delegates the action itself to attacker-controlled content -- than on precisely specified tasks. This is a structural limit: on such tasks the injection can pose as ordinary data rather than an explicit instruction, bypassing defenses that rely on detecting instruction-like text. AutoDojo is publicly available at https://github.com/xhOwenMa/AutoDojo.
LLM-based agents are increasingly deployed for complex tasks requiring planning, tool use, and interaction with external services. Their reliance on untrusted external content exposes them to indirect prompt injection (IPI), in which adversarial instructions embedded in retrieved data hijack agent behavior. Existing attacks rely on static payloads that cannot adapt to agent-specific defenses; even recent adaptive methods lack structured feedback to guide optimization. We introduce \oursys, a feedback-guided iterative framework that closes the loop between injection, diagnosis, and refinement: a rule-based diagnoser produces structured outcome labels with behavioral descriptions, and an LLM-based optimizer refines payloads conditioned on the full optimization history. A synthesis step generates new disguise seeds from failure patterns, enabling the strategy space to self-evolve. On AgentDojo and InjectAgent, \oursys substantially outperforms static baselines and existing adaptive methods across four victim models. Extension experiments on Claude Code, a production-grade coding agent with layered defenses, show that optimized payloads achieve full success on 5 of 9 targets; even those that resist full exploitation exhibit measurable improvement from iterative refinement. We further present a mechanistic analysis of IPI, identifying an attention-mediated threshold mechanism in mid-to-late layers; three causal interventions validate this finding and point to concrete defense directions.
Recent work (2024 to 2026) has converged on a strategy for defending tool-using LLM agents against indirect prompt injection: rather than training the model to refuse malicious instructions, enforce security outside the model with a deterministic policy that mediates the agent's actions. Systems such as CaMeL, FIDES, Progent, RTBAS, and FORGE realize this with capabilities, information-flow labels, and reference monitors, and several report near-elimination of attacks on the AgentDojo benchmark. We make two contributions. First, we organize these out-of-band defenses as instances of classical integrity protection (Biba), reference monitoring, and least privilege, yielding a structured comparison of what they do and do not cover. Second, we warn that every one of them is validated only on static benchmarks (a fixed set of injection attempts), the same methodology that made in-band defenses look strong until adaptive, defense-aware attacks broke twelve of them at over 90% success; we specify the threat model and protocol an adaptive evaluation requires. We then run that protocol as an independent reproduction and extension of Progent's own adaptive-attack analysis, on AgentDojo, with an open-weight agent (Qwen2.5-7B) self-hosted on a single H200, a setting its authors did not test. Averaged over three runs, the defense held: Progent cut mean attack success roughly sixfold (25.8% to 4.2%), and a hand-crafted adaptive attack did not raise it (2.6%). This is one small-scale data point on a weak model with a single black-box attack template; a stronger optimized (white-box GCG) attack remains open. The result is consistent with, but does not establish, the hypothesis that deterministic out-of-band enforcement is a harder target for an adaptive attacker than in-band detection.
Indirect prompt injection poses a critical threat to LLM agents that interact with untrusted external data, yet automated attack methods--proven effective for jailbreaking--remain underexplored in realistic agentic settings. We present a comprehensive empirical evaluation of automated prompt injection attacks against LLM agents, adapting both white-box (GCG) and black-box (TAP) methods to the agentic setting within the AgentDojo framework. We evaluate across 80 task pairs spanning four domains and multiple models, and find that black-box optimization substantially outperforms gradient-based methods, a gap we attribute to GCG's optimization instability under reasonable compute budgets. We also find that TAP's effectiveness depends on the attacker model, as both general capability and safety tuning affect attack success--stronger models produce more effective injections, while safety-tuned attackers can refuse to generate adversarial prompts. Task-universal attacks transfer effectively to unseen tasks and out-of-distribution domains, but attacks optimized on smaller open-source models do not transfer to frontier models like GPT-5. These findings highlight automated prompt injection as a credible but model-dependent threat, with significant barriers remaining for model-agnostic exploitation.