Authors: Fatih Kocabas, Cemal Polat Avdar, Prithvi Venkatesh, Yunus Alapan
Abstract
Acoustic microrobots have emerged as a promising frontier for targeted drug delivery and minimally invasive medicine due to their high-power density and biocompatibility. Despite wide-ranging designs, conventional acoustic microrobots mostly rely on air microbubbles trapped within confined microcavities within the robot body, which suffer from limited operational longevity due to rapid gas dissolution and resultant shifts in resonance frequency. In this paper, we propose a robust, membrane-based acoustic microrobot that overcomes these limitations by employing a thin flexible Polydimethylsiloxane (PDMS) membrane bonded over confined microcavities for microstreaming. The introduced design physically prevents gas diffusion, ensuring stable performance over extended periods at high actuation voltages. We systematically characterized the membrane-based acoustic actuator longevity, demonstrating consistent streaming and propulsion for over 24 hours of continuous operation. In addition, by embedding magnetic microparticles into the structural body, these actuators were successfully employed as microswimmers with directional control using low-intensity (2 mT) external magnetic fields. Finally, we demonstrate the scalability of the proposed design architecture down to ~100 um. This membrane-based approach establishes a reliable framework for the development of high-endurance acoustic microactuators and microrobots capable of performing long-term tasks.
Acoustic field-driven manipulation provides a non-contact and non-invasive strategy for controlling microscale and nanoscale objects, yet its extension to millimeter-scale robots was limited by insufficient propulsion efficiency in confined biological environments. Here, a coordinated multi-acoustic-field approach is introduced, which harnesses the synergistic action of acoustic radiation forces and acoustic streaming flows to enable controlled locomotion of millimeter-scale helical robots and enhance propulsion. Multiphysics simulations captured the dynamics of millimeter-scale helical robots under combined acoustic fields, and experimental validation demonstrated their locomotion capabilities, including planar navigation, inclined climbing, and vertical motion. Semi-autonomous navigation experiments further confirmed that ultrasonic synergy substantially improved maneuverability. In vitro tests in porcine venous vessels demonstrated that coordinated acoustic fields supported both unidirectional and reciprocating motion under biologically relevant confinement. These findings provide mechanistic insight into scaling acoustic micromanipulation to the millimetre regime and support biomedical applications requiring versatile and controllable robotic mobility.
Functional magnetic composites capable of large deformation, load bearing, and multifunctional motion are essential for next-generation adaptive soft robots. Here, we present muscle-inspired magnetic actuators (MMA), additively manufactured from a thermoplastic/permanent magnet polyurethane/Nd2Fe14B (TPU/MQP-S) composite using laser powder bed fusion (LPBF). By tuning the laser-energy scale between 1.0 and 3.0, both mechanical stiffness and magnetic response are precisely controlled: the tensile strength increases from 0.28 to 0.99 MPa while maintaining 30-45% elongation at break. This process enables the creation of 0.5 mm-thick flexural hinges, which reversibly bend and fold under moderate magnetic fields without damage. Two actuator types are reported showing the system versatility. The elongated actuator with self-weight of 1.57 g, magnetized in its contracted state, achieves linear contraction under a 500 mT field, lifting 50 g (32x its own weight) and sustaining performance over at least 50 cycles. Equipped with anisotropic frictional feet, it supports movement of a magnetic crawling robot that achieves up to 100% locomotion success on textured substrates. The expandable actuator exhibits reversible opening and closing under a 300 mT field, reliably grasping and releasing different objects, including soft berries and rigid 3D printed geometries. It can also anchor in a tube while holding suspended 50 g loads. This work demonstrates a LPBF-based strategy to program both stiffness and magnetization within a single material system, enabling remotely driven, reconfigurable, and fatigue-resistant soft actuators. The approach opens new possibilities for force controlled, multifunctional magnetic soft robots for adaptive gripping, locomotion, and minimally invasive manipulation of biomedical tools.
Muhammad Bilal Khan, Florian Hofmann, Kilian Schäfer +2
The capability to encode spatially distinct magnetization patterns within soft materials enables remote control over complex deformations. This characteristic is especially important for microfluidic platforms, where limited dynamic control of channel boundaries and laminar flow conditions usually restrict fluid transport and interactions. The present study introduces a shape-programmable magnetic soft membrane actuator as an active microchannel component that can dynamically modulate its shape under magnetic fields and therefore the microfluidic environment. The membrane is magnetically programmed using a template-based approach, which allows it to be controllably deformed in the form of a sinusoid under the influence of an external magnetic field. The membrane's integration into a microchannel converts a passive channel wall into a dynamically changeable interface, allowing active fluid manipulation and enhancing micromixing in laminar flow conditions. The proposed approach establishes a versatile platform for wirelessly controlled deformable interfaces in next-generation microfluidic and lab-on-chip systems.