Population-Level Profiling of DSM-5 Depressive Symptoms Among Self-Reported ADHD and ASD Users on Twitter: An Exploratory Study Using Advanced NLP and Statistical Analysis
Authors: Muhammad Rizwan, David Nabergoj, Jure Demšar
Organizations: Faculty of Computer and Information Science, University of Ljubljana, Slovenia
Abstract
Background: Depression frequently co-occurs with ADHD and autism spectrum disorder (ASD), but population-level differences in symptom expression between these groups remain underexplored. Objective: We examined whether social media users with ADHD and ASD differ in how they express DSM-5 depressive symptoms in their tweets, and whether differences persist across varying levels of depressive-content filtering. Methods: We analysed 1,282,437 tweets from 792 users (622 ADHD; 170 ASD) with self-reported diagnoses on Twitter. Tweets were pre-filtered for depressive relevance using zero-shot NLI, then classified into nine DSM-5 symptoms using MentalRoBERTa fine-tuned on ReDSM5. Profiles were mean-centered per user. We applied L1-penalised logistic regression with cross-validation to distinguish ADHD from ASD users, complemented by Pearson correlations for symptom co-occurrence, and tested robustness across five filtering thresholds using bootstrapping. Results: MentalRoBERTa achieved macro-F1 of 0.901 on a held-out set, outperforming the original ReDSM5 benchmark. ADHD vs ASD classification yielded stable but modest performance (cross-validated ROC-AUC 0.645-0.653). Cognitive issues, sleep issues, appetite change, and fatigue leaned toward ADHD, while suicidal ideation and anhedonia leaned toward ASD. A largely shared symptom co-occurrence structure emerged between groups; no pair met our criterion for a robust disorder-specific difference. Conclusions: Population-level differences in depression-related language between ADHD and ASD social media users were consistently observed across thresholds, reflecting reproducibility rather than clinical validity. Findings are exploratory and do not establish differing phenomenology at the individual level.
Depression is one of the most prevalent and debilitating mental health conditions worldwide, frequently underdiagnosed and undertreated. The proliferation of social media platforms provides a rich source of naturalistic linguistic signals for the automated monitoring of psychological well-being. In this work, we propose a system based on Large Language Models (LLMs) for depression risk assessment in Reddit posts, through multi-label classification of eight depression-associated emotions and the computation of a weighted severity index. The method is evaluated in a zero-shot setting on the annotated DepressionEmo dataset (~6,000 posts) and applied in-the-wild to 469,692 comments collected from four subreddits over the period 2024-2025. Our best model, gemma3:27b, achieves micro-F1 = 0.75 and macro-F1 = 0.70, results competitive with purpose-built fine-tuned models (BART: micro-F1 = 0.80, macro-F1 = 0.76). The in-the-wild analysis reveals consistent and temporally stable risk profiles across communities, with marked differences between r/depression and r/anxiety. Our findings demonstrate the feasibility of a cost-effective, scalable approach for large-scale psychological monitoring.
Computational mental health research has predominantly centered on English-speaking populations, leaving Arabic-language discourse comparatively under-examined. We present an exploratory computational study of 8,147 tweets from 607 users classified by a GPT-4.1 personal-disclosure pipeline as likely lived-experience authors in three condition-specific Arabic-language X (formerly Twitter) Communities. We focus on discourse related to borderline personality disorder (BPD), bipolar disorder, and ADHD, and characterize community-associated linguistic patterns using a multi-domain cultural keyword framework. The results suggest that in this corpus, Bipolar tweets contain more religious and medical vocabulary, BPD tweets contain more relational, identity, and emotional-distress vocabulary, and ADHD tweets more often focus on practical symptoms and medication management. We treat these patterns as hypothesis-generating rather than confirmatory because the corpus is imbalanced across conditions, some subcorpora are temporally concentrated, and the keyword framework is an initial operationalization rather than a validated measurement instrument. The paper contributes a reusable LLM-assisted personal-disclosure pipeline and an exploratory cultural keyword framework for Arabic mental health discourse.
Large language models are increasingly used as private, always-available conversational systems, but little is known about how people with depressive symptoms use them. Building on CSCW work on disclosure and peer support, we examine ChatGPT as an emerging informal support infrastructure: private, persistent, responsive, and available outside ordinary hours. We analyze 187,093 ChatGPT conversations from 766 participants who completed the PHQ-8, comparing those below the moderate-symptom threshold (score of 10) with those at or above it. Higher-PHQ participants used ChatGPT more for mental-health, interpersonal, loneliness, self-focused, and support-seeking conversations, with pronounced late-night and recurring month-level patterns. Their language contained more first-person singular pronouns and absolutist terms. They more often engaged ChatGPT in high-disclosure contexts, but professional redirection was not higher. Language-based prediction was modest and insufficient for screening (AUROC 0.591). We argue these histories should not be treated as clinical screening data but as evidence LLMs are increasingly used as informal support infrastructure.