cs.CLAug 30, 2026

Scientific Agent Skills: A Library of Procedural Knowledge for Research Agents

Authors: Timothy Kassis, Vinayak Agarwal, Yuhuan He, Darshil Patel, Aubrey M. Brueckner

Organizations: K-Dense, Inc.

Abstract

A language-model agent asked to analyse an experiment will usually return working code. Whether the analysis is defensible is a different question. A defensible analysis depends on procedural choices: which test the field accepts, which identifier namespace is authoritative, and which caveats must accompany a result. We present Scientific Agent Skills, an open library of 163 such procedures in 16 areas of practice, including genomics, cheminformatics, medical imaging, study design and scientific communication. Each skill is a directory built around a versioned, human-readable instruction file. An agent loads the file only when a task calls for it; the directory often also contains reference material and runnable scripts. We report no task-level evaluation and no host selection rate. We measure two properties of the documentation corpus: the always-resident descriptions of all 163 skills cost 7.1% of a 200,000-token window, and the median documented workflow fits within 23.9% of it, although 29 of 46 would overflow if every reference file were loaded. Openly licensed and available at https://github.com/K-Dense-AI/scientific-agent-skills.

Explore similar work

Jun 4, 2026cs.AI

SciVisAgentSkills: Design and Evaluation of Agent Skills for Scientific Data Analysis and Visualization

Recent advances in agentic visualization have enabled the translation of natural language into executable scientific visualization (SciVis) workflows. While general-purpose coding agents show strong capabilities, they often lack the tool-specific expertise required for SciVis tasks. In this work, we present SciVisAgentSkills, a collection of reusable agent skills that augment coding agents for scientific data analysis and visualization by encoding environment assumptions, tool usage patterns, and domain heuristics across scientific tools such as ParaView, napari, VMD, and TTK. We evaluate these skills on Codex and Claude Code using SciVisAgentBench, a benchmark of 108 expert-designed multi-step tasks. Results show that agent skills improve mean task scores across the evaluated suites, with token-efficiency benefits that depend on the agent harness and tool setting. These findings highlight the importance of structured procedural knowledge for enabling reliable, long-horizon SciVis workflows, while also showing that skills should be studied alongside the execution harness that loads and applies them. The skills are available at https://github.com/KuangshiAi/SciVisAgentSkills.
Kuangshi Ai, Haichao Miao, Kaiyuan Tang +2
Jun 10, 2026cs.CL

Notes2Skills: From Lab Notebooks to Certainty-Aware Scientific Agent Skills

Scientific discovery workflows rely heavily on lab notes, where researchers record observations, interpret uncertain results, and plan follow-up experiments. Unlike polished publications, lab notes preserve evolving scientific reasoning, tacit scientific knowledge, and author uncertainty, giving AI agents access to the process of science. However, most prior work on scientific text focuses on papers, protocols, or structured databases, leaving informal laboratory notes underexplored as inputs to AI agents for science. This gap matters because tacit knowledge in lab notes is not written as a clean set of instructions: validated observations, tentative judgments, and possible experimental next steps often appear in the same passage. If these signals are conflated, an AI agent may mistake uncertain scientific judgments for confirmed conclusions or executable actions. To this end, we present Notes2Skills, a two-stage framework for turning lab notebooks into verifiable skills for scientific AI agents while preserving the author's certainty. Across three wet-lab sessions and seven original downstream configurations, Notes2Skills is the only tested configuration that avoids both observed regime-level failures: over-acting on uncertain notes and missing firm directives. We show that certainty preservation is a key missing piece between lab notebooks and reliable agent skills, opening a path toward safer AI co-scientist systems.
Shi Liu, Jiayao Chen, Chengwei Qin +3
Jun 15, 2026cs.DL

Agentic Publication Protocol: An Attempt to Modernize Scientific Publication

Scientific publication is still organized primarily around static manuscripts, even though much of scientific progress depends on tacit know-how: how to run code, reproduce figures, interpret edge cases, choose useful follow-up directions, and avoid failed paths. Large language model agents create an opportunity to publish not only knowledge, but also operational know-how in a form that future readers and researchers can directly use. This paper outlines the Agentic Publication Protocol (APP), a lightweight repository format for packaging a paper together with code, data, environment information, reproducibility instructions, and an agent-facing instruction file. APP treats a version-controlled repository as the publication object and uses \texttt{AGENTS.md} and optional skills to define a paper agent that can explain the work, reproduce key results when possible, and support follow-up research. We describe the design principles and details of the protocol, as well as the agent skills useful for publishing papers under the protocol. We also describe development tools for evaluating and improving the protocol and associated agent skills. Finally, we provide a broader discussion of the future of scientific research in the agent era.
Sirui Lu, Xiao-Liang Qi