Initial condition recovery in nonlinear damped viscous photoacoustic tomography using a convolutional neural network-guided gradient-free optimization framework
Authors: Madhu Gupta, Anwesa Dey, Prapti Tala, Souvik Roy
Organizations: Department of Mathematics, Indian Institute of Technology, Gandhinagar, Gujarat, India. · Department of Mathematics, University of Utah, Salt Lake City, Utah, UT, USA. · Department of Mathematics, The University of Texas at Arlington, Arlington, TX, USA.
Photoacoustic tomography (PAT) is a hybrid imaging modality that combines high optical contrast with high ultrasonic resolution for biomedical imaging applications. In this work, we investigate the inverse problem of recovering the initial pressure distribution from boundary measurements in the presence of nonlinear acoustic propagation and viscous attenuation effects. To model these phenomena more accurately, we consider a nonlinear damped viscoelastic wave equation incorporating spatially varying sound speed, temporal attenuation, and nonlinear propagation mechanisms. We first establish the well-posedness of the corresponding forward problem using a Galerkin approximation combined with energy estimates and a fixed-point argument. For the inverse problem, we derive existence, uniqueness, and local uniqueness results under suitable assumptions through a harmonic extension reduction, spectral Laplace transform techniques, and observability estimates. To numerically reconstruct the initial pressure field, we develop a hybrid reconstruction framework that combines a convolutional neural network (CNN) with a gradient-free optimization strategy based on the sequential quadratic Hamiltonian (SQH) method derived from Pontryagin's maximum principle. The CNN is used to generate an informative initial guess, while the SQH framework enforces the governing PDE dynamics during the reconstruction process. Numerical experiments demonstrate that the proposed hybrid strategy significantly improves reconstruction quality, contrast, and robustness compared to standalone time-reversal and CNN-based approaches.
Figures & tables
Figure 1: Test Case 1: Reconstructions with two phantoms; Top row corresponds to the 2D profiles; Bottom row corresponds to a 1D cross sectional profile
Figure 2: Test Case 2: Reconstructions with 3 phantoms; Top row corresponds to the 2D profiles; Bottom row corresponds to a 1D cross sectional profile
Figure 3: Test Case 3: Reconstructions in 2D with the heart and lung phantom; Top row corresponds to the 2D profiles; Bottom row corresponds to a 1D cross sectional profile
Phantom
Test Case
TR
CNN
SQH
2 phantom
Test case 1
5.2e-3
4.3e-3
3.9e-3
3 phantom
Test case 2
1.1e-2
1.5e-2
8.8e-3
Heart and lung
Test case 3
1.1e-2
1.3e-2
8.9e-3
Table 1: MSE values for the various test cases.
Phantom
Test Case
TR
CNN
SQH
2 phantom
Test case 1
22.85
23.67
24.05
3 phantom
Test case 2
19.57
18.11
20.55
Heart and lung
Test case 3
19.57
8.86
20.51
Table 2: PSNR values for the various test cases.
Phantom
Test Case
TR
CNN
SQH
2 phantom
Test case 1
0.5
0.94
0.92
3 phantom
Test case 2
0.32
0.84
0.86
Heart and lung
Test case 3
0.33
0.48
0.87
Table 3: SSIM values for the various test cases.
Figure 4: Test Case 4: Reconstructions with 3 phantoms with space-time varying coefficients
Figure 5: Test Case 5: Reconstructions in 2D with the heart and lung phantom with space-time varying coefficients
Phantom
Test Case
TR
CNN
SQH
3 phantom
Test case 4
1.1e-2
1.5e-2
1.0e-2
Heart and lung
Test case 5
2.5e-2
1.4e-1
2.4e-3
Table 4: MSE values for the space-time varying coefficients test cases.
Phantom
Test Case
TR
CNN
SQH
3 phantom
Test case 4
19.57
18.11
19.86
Heart and lung
Test case 5
15.94
8.54
16.12
Table 5: PSNR values for the space-time varying coefficients test cases.
Phantom
Test Case
TR
CNN
SQH
3 phantom
Test case 4
0.32
0.84
0.86
Heart and lung
Test case 5
0.19
0.56
0.72
Table 6: SSIM values for the space-time varying coefficients test cases.
Department of Mathematics, University of Innsbruck Technikerstrasse 13, 6020 Innsbruck, Austria · Department of Computer Science, University of Innsbruck Technikerstrasse 21a, 6020 Innsbruck, Austria · Department of Mathematics, Yeungnam University 280 Daehak-Ro, Gyeongsan, Gyeongbuk 38541, South Korea
1Research Unit of Mathematical Sciences, University of Oulu, Finland · Department of Technical Physics, University of Eastern Finland, Finland · Department of Mathematics, University of Arizona, USA +2