MRI Reconstruction Risk Estimation from Inference Dynamics
Organizations: Technion · Institute of Science and Technology Austria
Abstract
Iterative MRI reconstructors produce intermediate estimates before returning a final image. We study these inference trajectories as a model-internal representation of realized reconstruction risk, measured by log-NMSE. Model-native states are projected to magnitude images, summarized by a fixed 16-dimensional descriptor, and mapped to risk using a source-trained ridge readout. Across three reconstruction backbones, trajectory features are strongly predictive of reconstruction risk on held-out source data. Under zero-shot target shift, their behavior is backbone-dependent, exhibiting both preserved positive association and readout reversal. Conditional analyses show that trajectory information can remain associated with error beyond an initialization-only predictor. A prefix analysis further shows that useful trajectory information can emerge before reconstruction completes. Repeated-mask and low-shot calibration studies indicate that trajectories primarily encode persistent case difficulty, while their orientation and calibration can change under domain shift.
Figures & tables
| Backbone | Steps | Projected state |
| XPDNet | 25 | primal-dual image estimate |
| VarNet | 12 | sensitivity-reduced cascade output |
| PromptMR+ | 12 | central image with five-slice context |
| XPDNet | VarNet | PromptMR+ | ||||
| Method | ||||||
| Trajectory | ||||||
| Hu-style | ||||||
| ResNet † | ||||||
| CQR | ||||||
| RM-RMS | ||||||
| Backbone | Trajectory | Hu-style | ResNet † |
| XPDNet | |||
| VarNet | |||
| PromptMR+ |
| XPDNet | VarNet | PromptMR+ | ||||
| Method | ||||||
| Trajectory | ||||||
| Hu-style | ||||||
| ResNet † | ||||||
| CQR | ||||||
| RM-RMS | ||||||
| Backbone | Trajectory | Hu-style | ResNet † |
| XPDNet | |||
| VarNet | |||
| PromptMR+ |
| Score | Pooled | Between | Within | Partial |
| Amplitude | ||||
| Trajectory | ||||
| Mask density | – | – | – |
Appendix figures & tables20 assets
Supplementary material from the paper’s appendix.
Appendix
| Stored name | Definition | Role |
| trajectory_path_length | Total normalized solver motion | |
| trajectory_endpoint_displacement | Net motion from initialization to output | |
| trajectory_path_efficiency | endpoint displacement divided by path length | Directness of the image path |
| trajectory_step_mean | mean of | Typical update magnitude |
| trajectory_step_std | population SD of | Variation in update magnitude |
| trajectory_step_max | maximum of | Largest update |
| Split | Method | 95% CI | 95% CI | ||
| Source | Trajectory | ||||
| Hu-style | |||||
| ResNet | |||||
| CQR | |||||
| RM-RMS | |||||
| Trajectory+Hu-style |
| Split | Method | 95% CI | 95% CI | ||
| Source | Trajectory | ||||
| Hu-style | |||||
| ResNet | |||||
| CQR | |||||
| RM-RMS | |||||
| Trajectory+Hu-style |
| Split | Method | 95% CI | 95% CI | ||
| Source | Trajectory | ||||
| Hu-style | |||||
| ResNet | |||||
| CQR | |||||
| RM-RMS | |||||
| M4Raw | Trajectory |
| Backbone | Split | Method | RMSE SD | 95% CI |
| XPDNet | Source | Trajectory | ||
| Hu-style | ||||
| ResNet | ||||
| M4Raw | Trajectory | |||
| Hu-style | ||||
| ResNet |
| Backbone | Difference | 95% CI | 95% CI | ||
| VarNet | Trajectory Hu-style | ||||
| Trajectory ResNet | |||||
| Trajectory CQR | |||||
| Trajectory RM-RMS | |||||
| PromptMR+ | Trajectory Hu-style | ||||
| Trajectory ResNet |
| Backbone | Prediction corr. | Partial measure | Trajectory given Hu-style | Hu-style given trajectory |
| PromptMR+ | Pearson | |||
| Spearman | ||||
| VarNet | Pearson | |||
| Spearman | ||||
| XPDNet | Pearson | |||
| Spearman |
| Backbone | Split | Measure | Trajectory given | given trajectory |
| PromptMR+ | Source | Pearson | ||
| Spearman | ||||
| M4Raw | Pearson | |||
| Spearman | ||||
| VarNet | Source | Pearson | ||
| Spearman |
| Backbone | Split | Full | -independent | ||
| VarNet | Source | ||||
| M4Raw | |||||
| PromptMR+ | Source | ||||
| M4Raw | |||||
| Prefix | Source | Source | Source RMSE | Target | Target |
| 12/25 | |||||
| 25/25 |
| Backbone | Pearson | Spearman |
| XPDNet | ||
| VarNet | ||
| PromptMR+ |
| Backbone | Score | Source | Source | M4Raw | M4Raw |
| VarNet | Final DC residual | ||||
| Endpoint amplitude | |||||
| Trajectory+controls | |||||
| PromptMR+ | Final DC residual | ||||
| Endpoint amplitude | |||||
| Trajectory+controls |
| Split | Mean | Median | 5th pct. | 95th pct. |
| Source | ||||
| M4Raw |
| Patients | Traj. RMSE | Constant RMSE | Difference | Test |
| 4 | ||||
| 8 | ||||
| 16 |
| Seed | Source | Source | Source RMSE | Target | Target | Target RMSE |
| Reported run | ||||||
| 20260816 | ||||||
| 20260817 |
| Predictor | RMSE | MAE | ||
| Amplitude | ||||
| Trajectory | ||||
| Combined | ||||
| Difference | and 95% CI | RMSE and CI | MAE and CI | |
| Trajectory amplitude | ||||
| Combined trajectory | ||||
| Score | Pooled | Between | Within | Partial |
| Amplitude | ||||
| Trajectory | ||||
| Mask density | – | – | – |
| Cohort | Model | Slope | 95% CI |
| Adaptation | Pooled | ||
| Patient+acquisition | |||
| Strict | |||
| Confirmation | Pooled | ||
| Patient+acquisition | |||
| Strict |
| Patients | Constant | Amplitude | Trajectory | Traj. constant | Traj. amplitude | Reduction |
| 4 | ||||||
| 8 | ||||||
| 16 |
| Measurement | Value |
| Replicated relation-direction cosine | |
| Cosine with negative loss gradient | |
| Single-case true-gradient PSNR change | dB |
| Single-case reverse predicted-direction PSNR change | dB |
Image Reconstruction
Image reconstruction recovers images, volumes, or scenes from incomplete, noisy, indirect, or compressed measurements using physical models and learned priors.
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