Quantization-Aware LoRA

Background: Protein language models (PLMs) are increasingly used for sequence generation and property prediction, but their size makes fine-tuning and deployment expensive. The effects of quantization and parameter efficient fine-tuning on performance, representations and generation remain insufficiently characterized. Results: We evaluated 4-bit quantization and low-rank adapter fine-tuning (QLoRA) across ESM-2, ESMC, ProtBERT, ProtT5, Ankh, Ankh3 and Profluent-E1. Across protein prediction tasks, many model-task pairs retained more than 90% of full fine-tuning performance. Peak GPU memory savings approached 90% for the largest models, although performance and efficiency varied by model, dataset and training configuration. QLoRA often preserved early-layer representations while inducing task-specific adaptations in middle and late layers, resembling full fine-tuning with smaller representational changes. Training speed and power effects were more varied. For unconditional generation with ProLLaMA, ProtGPT2, ProGen2, ProteinGLM and ESM3, 4-bit quantization largely preserved predicted structural and sequence-level properties, but token-level analysis revealed model-dependent shifts in autoregressive output distributions. Conclusion: QLoRA and 4-bit quantization reduce PLM computational requirements, particularly GPU memory usage. Our results support QLoRA as a first-pass strategy for memory limited adaptation, reserving full fine-tuning for challenging tasks, unstable architectures or low validation recovery. For generative PLMs, sequence-level and structural metrics should be complemented with distributional analysis, since downstream predictions alone may miss quantization-induced shifts. These approaches can broaden access to large-scale protein modelling while requiring model- and task-specific validation.

This study explores the optimization of the Phi-2 Small Language Models (SLMs) for real-time chatbot applications through Parameter-Efficient Fine-Tuning (PEFT) and Quantized Low-Rank Adaptation (QLoRA). QLoRA specifically refers to the integration of PEFT with LoRA alongside a 4-bit quantization process, aimed at enhancing computational efficiency. These models, initially designed for high performance with minimal computational overhead, are further refined to address the constraints of mobile and edge computing environments. By integrating PEFT with QLoRA, the research aims to reduce memory usage significantly while maintaining, or potentially improving, the accuracy of model responses in real-time interactions. The effectiveness of these techniques was evaluated using the ROUGE metric system, which showed notable improvements in the summarization tasks performed by the models. This approach not only confirms the feasibility of using SLMs in resource-restricted environments but also opens up new avenues for deploying advanced AI-driven applications in real-time settings. The study's findings have significant implications for the development of efficient, scalable, and accessible AI technologies, paving the way for broader adoption in various industries.

Financial sentiment classifiers are commonly evaluated against human labels, but strong linguistic performance does not necessarily imply economically useful return predictability. This study separates these questions through two experiments. First, we construct a unified three-class benchmark from five financial text datasets and compare TF--IDF Naive Bayes, off-the-shelf FinBERT and Financial-RoBERTa encoders, zero-shot Qwen2.5-7B, and QLoRA-adapted Qwen2.5-7B, LLaMA3-8B, and Mistral-7B models. Mistral-7B achieves the best test accuracy (0.8840) and macro-F1 (0.8771), while QLoRA raises Qwen2.5's macro-F1 from 0.7274 to 0.8615. An inverse-frequency class-weighted loss does not improve Qwen2.5. Second, we evaluate economic validity on a temporally separate 2019 Benzinga sample containing 10,637 unique headlines and 13,115 headline--stock observations for a fixed S&P~100 universe. Model probabilities are converted into continuous sentiment scores, aggregated by stock and signal date, and aligned with next-session returns over one-, two-, three-, and five-day horizons. All seven downstream models produce positive but small mean rank information coefficients at the one-day horizon; the largest is 0.0143 for FinBERT. None of the 28 model--horizon tests remains significant after Newey--West inference and false-discovery-rate correction. Portfolio results likewise fail to establish a robust advantage for the best-performing classifiers. The findings show that QLoRA is effective for financial sentiment adaptation, while also documenting a clear gap between classification accuracy and tradable cross-sectional signals.

Parameter-Efficient Fine-Tuning (PEFT) commonly adapts large language models using a single shared Low-Rank Adapter (LoRA). This shared optimization space often suffers from interference when adapting heterogeneous task sequences, leading to poor transfer and catastrophic forgetting. Existing approaches mainly improve adapter expressiveness by increasing parameter capacity or composing multiple adapters, yet they still rely on a shared optimization path. In this paper, we propose an optimization-path organization framework for parameter-efficient fine-tuning of large language models, implemented as an automatic multi-policy PEFT architecture. Specifically, optimization-compatible adaptation paths are automatically organized through task grouping and task sequencing under a fixed parameter budget. The organized optimization paths are implemented as independent Quantized Low-Rank Adapters (QLoRA), enabling heterogeneous tasks to be optimized in decoupled adaptation spaces while preserving positive transfer among compatible tasks. Experiments on the TRACE benchmark demonstrate that performance consistently improves from conventional single-policy PEFT to multi-policy PEFT, with the proposed automatic multi-policy framework achieving the best performance of 44.78 under the same trainable capacity. This suggests that optimization-path organization is more effective than simply increasing adapter capacity for heterogeneous parameter-efficient fine-tuning.

Bridge infrastructure deteriorates gradually, yet its root causes---salt intrusion, freezing, fatigue cracking, and others---remain invisible to the naked eye. Expert diagnosis relies on tacit knowledge built over years of practice. We address the challenge of automating this latent causal reasoning by proposing a Damage Cause Encoder that classifies 10-class damage causes from visible damage descriptions $S_i$ for use in autonomous bridge diagnostic agents. Our approach chains three components: (i)Knowledge Triple Extraction---a large language model extracts causal triples of the form (damage $\xrightarrow{\mathtt{caused\_by}}$ cause) from 15--35 diagnostic PDF manuals and indexes them in a FAISS vector store; (ii)Retrieval-Augmented Context---at training and inference time, relevant causal triples $\mathcal{C}_i$ are retrieved and concatenated with $S_i$, converting implicit domain knowledge into explicit Encoder context; (iii)Systematic Fine-tuning Comparison---we conduct a rigorous comparison of LoRA, QLoRA, and QA-LoRA on a fixed Golden Testset (116 stratified samples), demonstrating that QLoRA achieves the optimal trade-off: identical test accuracy (87.07%) to full-precision LoRA, 11% faster inference, 72% lower GPU memory, and superior generalization across diverse unseen inputs. A controlled Golden Testset---stratified, deduplicated, and difficulty-tagged---is introduced as a reusable benchmark contribution. QLoRA further outperforms LoRA by 13 percentage points on a 100-sample diverse evaluation spanning all 10 damage cause classes.These findings enable memory-efficient, high-accuracy diagnostic agents on consumer-grade hardware for edge deployment.

Researchers are interested in learning about Mars so that it may eventually become habitable for humans. To achieve this, there is a need for comprehensive knowledge of the planet's atmosphere, hydrology, surface chemistry, radiation environment, and spatial features through the scientific literature. These contain valuable information and meaningful quantitative constraints that can be used in other models and studies, such as habitability assessment and future terraforming studies. We present TerraMARS, an end-to-end information extraction pipeline that combines a domain-adapted Small Language Model to answer Mars terraforming-related questions and convert unstructured Mars science text into machine-readable structured outputs in JavaScript Object Notation (JSON) format. A corpus of open-access papers is collected and processed using a multistage retrieval and chunking framework. Google Gemma 3 1B was adapted to the domain using Quantized Low-Rank Adaptation (QLoRA) fine-tuning on Mars-specific question-answering and information extraction datasets. The resulting pipeline generates both types of output and provides a foundation for integrating knowledge from scientific literature into downstream applications like digital twins and habitability modeling for Mars. The output from this pipeline looks promising, but further improvements are needed to increase extraction accuracy and factual consistency.

Large Language Models such as GPT-4o and GPT-5 achieve strong zero-shot performance on biomedical claim verification, but cost and opacity limit scalable use. We fine-tune three small LLMs: Phi-3-mini (3.8B), Qwen2.5-3B, and Mistral-7B, via QLoRA on SciFact and HealthVer, providing the first study of QLoRA models against GPT-4o and fine-tuned BioLinkBERT encoders. Mistral-7B QLoRA surpasses both GPT-4o and GPT-5 (up to 12% F1 gain) at a fractional cost using just 1,008 training examples. We conduct extensive in-domain and cross-domain evaluation: models trained on SciFact tested on HealthVer and vice versa, at matched sizes to isolate dataset structure from data quantity. We identify a previously unreported structural artifact in SciFact that inflates in-domain scores, and show through bidirectional out-of-domain evaluation that training on structurally sound data enables robust cross-domain transfer. We plan to release all code and adapter checkpoints.

Detecting psychological defense mechanisms in conversational text remains a challenging clinical NLP problem. For the PsyDefDetect 2026 shared task (nine-class utterance classification evaluated via macro F1), our team LinguIUTics achieves a macro F1-score of 0.3917 on the official positive-class leaderboard, ranking 4th out of 21 registered teams and improving over the Ministral-8B task baseline (31.48 macro F1) by 7.7 absolute points (24.4 percent relative). BERT-family encoders and zero-shot LLMs proved ineffective on rare classes due to severe class imbalance, leading us to QLoRA fine-tuning of Qwen3-8B. We leverage three key strategies: grouped stratified cross-validation (preventing leakage), minority-class round-robin lexical augmentation, and a post-processing pipeline with logit bias tuning and ensemble blending. Together, these components close much of the validation-to-leaderboard gap and substantially improve minority-class recall, driving the critical "Unclear" class (Level 8) from near-zero performance to an F1 score of 0.797.

On-device adaptation of large language models commonly keeps a quantized base model frozen while training and deploying a small, task-specific LoRA adapter. In the unmerged adapter-mode setting, however, the adapter is more than a compact storage module; it introduces an additional dense floating-point branch, maintains a trainable state for local updates, and acts as a unit of communication and hot-swapping.We introduce LoRDBA, a LoRA-compatible adapter that replaces both low-rank factors with binary sign carriers while representing magnitudes through lightweight, channel-wise scales, converting the dense adapter branch into two sign-accumulation matrix multiplications interleaved with channel-wise scaling. A finite-sample analysis shows that reconstruction quality is governed by the residual-to-magnitude ratio of the original LoRA factors. In adapter-mode experiments, LoRDBA outperforms low-bit baselines at matched model sizes while matching fp16 LoRA quality in selected regimes. The unmerged adapter incurs at most 8% prefill latency overhead at matched rank r=16 despite an over 10x reduction in adapter footprint, with moderate training memory overhead of approximately 1.6x that of fp16 LoRA.

As increasingly large pre-trained models are released, deploying them on edge devices for privacy-preserving applications requires effective compression. Recent works combine quantization with the fine-tuning of high-precision LoRA adapters, which can substantially reduce model size while mitigating the accuracy loss from quantization. However, edge devices have inherently heterogeneous capabilities, while performing configuration-wise fine-tuning for every quantization setting is computationally prohibitive. In this paper, we propose CoA-LoRA, a method that dynamically adjusts the LoRA adapter to arbitrary quantization configurations (i.e., the per-layer bit-width choices of a pre-trained model) without requiring repeated fine-tuning. This is accomplished via a configuration-aware model that maps each configuration to its low-rank adjustments. The effectiveness of this model critically depends on the training configuration set, a collection of configurations chosen to cover different total bit-width budgets. However, constructing a high-quality configuration set is non-trivial. We therefore design a Pareto-based configuration search that iteratively optimizes the training configuration set, yielding more precise low-rank adjustments. Our experiments demonstrate that, unlike the state-of-the-art methods that require fine-tuning a separate LoRA adapter for each configuration, CoA-LoRA incurs no additional time cost while achieving comparable or even superior performance to those methods.