Contact-rich micromanipulation in microfluidic flow is challenging because small disturbances can break pushing contact and induce large lateral drift. We study planar cell pushing with a magnetic rolling microrobot that tracks a waypoint-sampled reference curve under time-varying Poiseuille flow in simulation. We propose a hybrid controller that augments a nominal MPC with a learned residual policy trained by SAC. The policy outputs a bounded 2D velocity correction that is contact-gated, so residual actions are applied only during robot-cell contact, preserving reliable approach behavior and stabilizing learning. All methods share the same actuation interface and speed envelope for fair comparisons. Simulation results show improved robustness and tracking accuracy over pure MPC and PID under nonstationary flow, with generalization from a clover training curve to unseen circle and square trajectories. A residual-bound sweep identifies an intermediate correction limit as the best trade-off, which we use in all benchmarks.
Developing learning-based autonomy for microrobotic manipulation is difficult because physical trials are slow, variable, and poorly suited to large-scale training. We present MicroPush, a lightweight simulation and benchmarking environment for pushing and assembly with magnetic rolling microrobots. The simulator combines overdamped planar dynamics with calibrated rolling actuation, reduced-order contact handling, short-range interaction corrections, and optional background flow, while providing common interfaces for planning, model-based control, reinforcement learning (RL), interactive visualization, and headless evaluation. In no-render tests, MicroPush remains substantially faster than real time, reaching 37.0x real time with 100 passive particles. We further evaluate the simulator through zero-shot sim-to-real policy transfer. A Residual RL-MPC policy is trained entirely in MicroPush, frozen after simulation training, and deployed on the physical system without real-world policy fine-tuning. A 20 μm magnetic microrobot pushes a similarly sized silica particle along a figure-eight trajectory with 1.91 μm median and 4.65 μm 95th-percentile path error, and the same autonomy stack performs sequential line, triangle, and six-particle hexagonal assembly. These results show that a deliberately reduced-order simulator can provide an efficient training and development substrate for sim-to-real microrobotic autonomy.
Coordinating micro-robotic swarms in realistic, time-dependent fluid environments remains a major challenge for biomedical and environmental applications. We present a hybrid CFD-MO-MARL (Computational Fluid Dynamics-Multi Objective-Multi Agent Reinforcement Learning) framework that couples a high-fidelity incompressible Navier--Stokes solver with decentralized proximal policy optimization to learn swarm control policies in oscillatory flow. Sixteen magnetically actuated micro-robots were simulated to navigate a pulsatile arterial waveform within a 2 mm channel while jointly optimizing upstream progression, energy efficiency, and motion smoothness. Conflicting objectives are resolved using Projected Conflicting Gradient (PCGrad) surgery. Without PCGrad, energy and smoothness rewards collapse during training, demonstrating that gradient conflict resolution is essential for stable multi-objective learning. The converged policy achieves progress rewards of 6.5-7.0, energy efficiency of 0.63-0.65, and smoothness of 0.97-0.99, outperforming brute-force baselines by more than 8 reward units on the primary objective. Training reveals three emergent behaviors not encoded in the reward function: hydrodynamic throttling formations that reduce peak flow velocities, a cycle-synchronized ratchet mechanism that exploits flow reversals for upstream movement, and individualized final-approach strategies near the target boundary. These results demonstrate that physically realistic fluid--agent interactions can be integrated directly into multi-objective reinforcement learning, providing a scalable framework for micro-swarm control in biomedical navigation, environmental monitoring, and microfluidic systems.
Autonomous microrobots navigating biological vasculature could enable targeted drug delivery and thrombolysis, yet training control policies for realistic environments remains an open challenge. Prior reinforcement learning (RL) studies of microrobotic navigation have been limited to idealized geometries that omit complex hydrodynamic flow fields, confined branching structures, and dense cellular obstacles found in vivo. Here, we develop a physically grounded simulation of a blood capillary network, incorporating realistic hydrodynamic flow fields, explicit red blood cell dynamics, and anatomically derived branching geometry, and train deep RL agents to navigate it via chemotaxis. We systematically map the physical limits of navigation across robot size and swimming speed, revealing a forbidden regime where Brownian motion and flow overcome propulsion. Successful agents independently discover multiple universal strategy types, including run-and-rotate and energy-efficient search-and-sit policies, regardless of robot parameters. Without retraining, these agents perform targeted blocking and unblocking of capillary flow, restoring throughput to healthy baseline levels. These results establish RL as a viable framework for developing autonomous microrobotic intervention strategies in complex biological environments.
Jannik Drotleff, Samuel Tovey, Paul Hohenberger +4