Versatile Exoskeleton Control Supports Elderly Joint Energetics During Hip-Intensive Tasks

Biological torque control directly maps an estimated human joint moment to exoskeleton assistance, providing a task-agnostic strategy for supporting diverse locomotor activities. However, it remains unclear whether a fixed state-to-torque mapping provides effective assistance across biomechanically distinct tasks. We examined how assistance delay affected hip exoskeleton performance during level-ground (LG), ramp-ascent (RA), and ramp-descent (RD) walking. Eight participants completed a zero-torque baseline condition and five active assistance conditions with delays ranging from 40 to 320 ms. Across tasks and active delays, assistance reduced net metabolic rate by 5.24%, positive biological hip joint work by 5.86%, and total lower-limb positive joint work by 1.68% (all p < 0.05). Assistance delay affected both joint-work outcomes (both p < 0.001) but not net metabolic rate. Mechanical unloading generally decreased with increasing delay, whereas metabolic benefits remained comparatively stable. Relative to the zero-torque condition, net metabolic rate decreased by 9.75% during LG and 7.20% during RA but increased by 1.23% during RD. We did not detect task-dependent differences in the delay response. Our findings indicate that biological torque mappings should be evaluated based on the target outcome and mechanical role of the assisted joint, and that predominantly positive-power assistance may not generalize to negative-work-dominant locomotion without modification.

Learning-based controllers can deliver exoskeleton assistance after training entirely in physics-based simulation, yet few controllers that address human-device co-adaptation have been validated on real users by whole-body metabolic measurement, the standard benchmark for assistive walking. Co-adaptation is challenging: as the device alters joint dynamics, the wearer reorganizes neuromuscular coordination, producing a non-stationary learning problem. Staged Multi-Agent Training (SMAT), a four-stage curriculum that progressively trains a musculoskeletal human actor and a bilateral hip exoskeleton actor, was introduced and shown to reduce simulated hip-muscle activation and provide positive assistance on hardware. This article provides the first physiological validation of SMAT. The policy was deployed on a hip exoskeleton and tested with eight healthy adults, with metabolic cost measured by indirect calorimetry across no-exoskeleton, passive, and active conditions. Active assistance lowered net metabolic rate by 19.7% relative to the passive device (p < 0.001). Biomechanical analysis confirmed predominantly positive hip mechanical power across all subjects (positive-power ratio 0.98), and the policy generalized across walking speeds and terrains. Together, these results show that a single simulation-trained SMAT policy, deployed without subject-specific retraining, delivers a significant metabolic benefit on real users while remaining robust beyond the conditions it was trained on.

Developing exoskeleton controllers that generalize across diverse locomotor conditions typically requires extensive motion-capture data and biomechanical labeling, limiting scalability beyond instrumented laboratory settings. Here, we present a physics-based neuromusculoskeletal learning framework that trains a hip-exoskeleton control policy entirely in simulation, without motion-capture demonstrations, and deploys it on hardware via policy distillation. A reinforcement learning teacher policy is trained using a muscle-synergy action prior over a wide range of walking speeds and slopes through a two-stage curriculum, enabling direct comparison between assisted and no-exoskeleton conditions. In simulation, exoskeleton assistance reduces mean muscle activation by up to 3.4% and mean positive joint power by up to 7.0% on level ground and ramp ascent, with benefits increasing systematically with walking speed. On hardware, the assistance profiles learned in simulation are preserved across matched speed-slope conditions (r: 0.82, RMSE: 0.03 Nm/kg), providing quantitative evidence of sim-to-real transfer without additional hardware tuning. These results demonstrate that physics-based neuromusculoskeletal simulation can serve as a practical and scalable foundation for exoskeleton controller development, substantially reducing experimental burden during the design phase.