Anatomical Landmark-Guided Deep Reinforcement Learning for Autonomous Gastric Navigation

Autonomous endoscopic navigation can reduce clinicians' operational burden, yet robust control remains challenging due to tissue deformation, transient occlusions, and rapidly changing viewpoints. Existing learning-based policies typically predict actions from current observations without explicitly modeling future dynamics, limiting their robustness and reliability in safety-critical settings. World Action Models (WAMs) offer a promising alternative by coupling predictive visual dynamics with action generation, but extending them to robotic endoscopy remains challenging due to limited training data, restricted viewpoint diversity, deformable anatomy, and high inference latency. We present EndoWAM, which is, to our knowledge, the first WAM for generalizable robotic endoscopic navigation. EndoWAM introduces future grounding, which predicts task-relevant target regions in future observations from intermediate denoising features of a video world model. Specifically, EndoWAM couples a lightweight diffusion transformer for future target-region prediction with a discrete action expert through a shared predictive representation. This design injects target-aware supervision into predictive dynamics modeling, improving robustness to visual degradation and viewpoint changes while enabling real-time control in a single denoising pass. We further introduce EndoMotion, a robotic endoscopic motion dataset spanning three anatomically distinct procedures: ureteroscopy, esophagoscopy, and endoscopic retrograde cholangiopancreatography (ERCP). EndoWAM consistently outperforms all baselines and alternative grounding strategies, while demonstrating strong zero-shot generalization to unseen viewpoints, environments, and targets. These results establish EndoWAM as a predictive, target-grounded framework for accurate, generalizable, and long-horizon navigation in visually constrained endoscopic environments.

Autonomous endoscopic navigation requires the policy model to predict actions from texture-poor monocular observations, make safe control decisions, and retain evidence of lesions after they leave the field of view. Existing vision-language-action (VLA) models primarily rely on visual appearance and short-term context, limiting geometric grounding and episode-level reporting. We introduce StenoVLA-3D, a 3D-aware VLA framework for navigating through stenotic regions. We integrate point-maps into the Cosmos-Reason 2 backbone through learned geometry-gated fusion, and also propose a temporal state branch to model traversal progress. Our reasoning-and-action backbone predicts grounded reasoning with actions, while dedicated heads estimate stenosis shape and generate the final lesion report. We further introduce EndoCausal, an episode-level dataset with lesion annotations, actions, and temporally grounded reasoning. On 40 held-out recorded test episodes, StenoVLA-3D reaches 95.2% semantic accuracy and 83.4% action accuracy. On the physical 3-DoF endoscope, it attains 88.9% and 77.8% task success in esophageal and colonic phantoms (36 trials each), substantially outperforming the evaluated baselines.

Endoscopic retrograde cholangiopancreatography (ERCP) demands precise endoscopic navigation and stable biliary cannulation within a narrow monocular field characterized by specular reflections, partial occlusions, and frequent tissue contact. Although recent robotic systems and vision-based assistance techniques improve operator ergonomics and provide perceptual cues, their performance degrades under pronounced anatomical variability and safety-critical visual artifacts, which hinders reliable autonomy in cannulation-grade procedures. Here, we present BiliVLA, a scene-aware Vision-Language-Action (VLA) framework that formulates biliary endoscopic navigation as an instruction-conditioned visuomotor learning problem. Given an endoscopic observation and a stage-specific language instruction, BiliVLA jointly predicts the target category, a grounded bounding box, and a discrete three-degree-of-freedom (3-DoF) motor command for a continuum endoscope. The proposed framework incorporates scene-aware supervision to improve semantic target consistency and safety-aware recovery supervision to induce conservative retreat behaviors under luminal wall contact. A key component of BiliVLA is a two-stage training paradigm that combines grounding-enhanced supervised fine-tuning (SFT) with Group Relative Policy Optimization (GRPO), thereby improving action reliability and decision consistency during closed-loop navigation. Across three ERCP subtasks, BiliVLA achieves the best overall performance in physical phantom experiments, with a total mIoU of 0.9625, an overall action precision of 91.96%, and an overall success rate (SR) of 84.85%. These results indicate that integrating semantic grounding, scene-aware learning, and reward-guided optimization strengthens perception--action alignment and enables more robust autonomous biliary endoscopic navigation.