Echo4DIR: 4D Implicit Heart Reconstruction from 2D Echocardiography Videos
Authors: Yanan Liu, Qinya Li, Hao Zhang, Kangjian He, Xuan Yang, Hao Li, Dan Xu, Lei Li
Organizations: Department of Biomedical Engineering, National University of Singapore, Singapore · School of Information Science and Engineering, Yunnan University, Kunming, China
Abstract
Reconstructing 4D (3D+t) cardiac geometry from sparse 2D echocardiography is highly desirable yet fundamentally challenged by geometric ambiguity and temporal discontinuity. To tackle these issues, we propose Echo4DIR, a novel test-time 4D implicit reconstruction framework. Specifically, we learn robust 3D shape priors from statistical shape models (SSMs) via a cardiac conditional SDF, constructing an Epipolar Mask Encoder module with epipolar cross attention to effectively fuse multi-view features. To bridge the synthetic-to-real domain gap, we introduce a self-supervised SDF-tailored differentiable rendering strategy for patient-specific 3D shape adaptation using uncalibrated clinical masks without requiring 3D ground truth. Crucially, the inherent continuity of implicit representation overcomes sparse observations, enabling anatomically reliable geometry at arbitrary resolutions. Furthermore, to empower our framework with physically continuous 4D extension, we introduce a Radial SDF Alignment strategy that strictly locks shape evolution to the predicted velocity field, fundamentally eliminating mesh drift. Extensive experiments on synthetic benchmarks and real clinical datasets demonstrate that Echo4DIR achieves state-of-the-art 4D cardiac mesh reconstruction, notably yielding an impressive clinical overlap of up to 98.35% Dice and 96.75% IoU.
Accurate 3D+t whole-heart mesh reconstruction from cine MRI is a clinically crucial yet technically challenging task. The difficulty of this task arises from two coupled factors: inherently sparse sampling of 3D cardiac anatomy by 2D image slices and the tight coupling between cardiac shape and motion. Current cardiac image-to-mesh approaches typically reconstruct only a subset of cardiac chambers or a single phase of the cardiac cycle. In this work, we propose CineMesh4D, a novel end-to-end 4D (3D+t) pipeline that directly reconstructs patient-specific whole-heart mesh from multi-view 2D cine MRI via cross-domain mapping. Specifically, we introduce a differentiable rendering loss that enables supervision of 3D+t whole-heart mesh from multi-view sparse contours of cine MRI. Furthermore, we develop a dual-context temporal block that fuses global and local cardiac temporal information to capture high-dimensional sequential patterns. In quantitative and qualitative evaluations, CineMesh4D outperforms existing approaches in terms of reconstruction quality and motion consistency, providing a practical pathway for personalized real-time cardiac assessment. The code will be publicly released once the manuscript is accepted.
Accurate 4D whole-heart mesh reconstruction from sparse cine MRI is critical for creating cardiac digital twins, but remains challenging due to limited 2D slice coverage and the complex coupling between cardiac shape and motion. Existing methods often rely on intermediate contour fitting and typically reconstruct static, single-phase, or partial cardiac geometries, limiting their ability to capture full-chamber dynamics. We propose a novel end-to-end framework for reconstructing temporally resolved whole-heart meshes from multi-view 2D cine MRI sequences by learning an image-to-mesh mapping. The framework incorporates a differentiable contour renderer inspired by the Beer-Lambert attenuation principle, enabling anatomy-aware supervision of 3D+t mesh deformation through contour-based projection losses. To improve temporal consistency across the cardiac cycle, we further introduce a multi-scale temporal modeling module that integrates global cycle-level dynamics with local inter-frame coherence to generate smooth and physiologically plausible mesh trajectories. The proposed method achieved a whole-heart mean absolute error of 1.68 ± 0.31 mm and a motion jitter of 0.77 ± 0.17 mm/frame3, outperforming existing methods with lower reconstruction error and substantially improved motion smoothness. It also improved 2D contour alignment across multiple cine MRI views and supported downstream proof-of-concept electrophysiological simulation. The code will be released publicly upon acceptance of the manuscript for publication.
Accurate cardiac anatomy modeling requires the model to be able to handle intricate interrelations among structures. In this paper, we propose VecHeart, a unified framework for holistic reconstruction and generation of four-chamber cardiac structures. To overcome the limitations of current feed-forward implicit methods, specifically their restriction to single-object modeling and their neglect of inter-part correlations, we introduce Hybrid Part Transformer, which leverages part-specific learnable queries and interleaved attention to capture complex inter-chamber dependencies. Furthermore, we propose Anatomical Completion Masking and Modality Alignment strategies, enabling the model to infer complete four-chamber structures from partial, sparse, or noisy observations, even when certain anatomical parts are entirely missing. VecHeart also seamlessly extends to 3D+t dynamic mesh sequence generation, demonstrating exceptional versatility. Experiments show that our method achieves state-of-the-art performance, maintaining high-fidelity reconstruction across diverse challenging scenarios. Code is available at https://github.com/Scalsol/VecHeart.