Organizations: East China Normal University Shanghai, China · City University of Hong Kong Hong Kong SAR, China
Abstract
The intricate nature of modern surgical care necessitates intelligent systems that can synthesize extensive patient records, support collaborative decision-making, and provide transparent, auditable reasoning across the entire perioperative workflow. Although web-based Large Language Models (LLMs) possess advanced reasoning capabilities, they are ill-equipped for surgical applications due to critical limitations: input length constraints, incomplete memory management, and limited traceability. To address this issue, we present SURGENT, a surgical multi-agent assistance system that combines a Tree-of-Thought planner, multi-department collaboration agents, and retrieval-augmented reasoning with clinical guidelines and biomedical literature. SURGENT features a novel memory design that manages both long-term patient histories and short-term working summaries, enabling more complete, contextualized, and consistent reasoning. Experimental evaluations across five key perioperative tasks - case analysis, surgical plan simulation, safety monitoring, complication risk assessment, and rehabilitation guidance - show that SURGENT outperforms baseline LLMs and existing medical multi-agent frameworks, yielding recommendations more closely aligned with patient histories. Ablation studies further highlight the advantage of DeepSeek as a locally deployable backbone model, enabling privacy-preserving deployment without reliance on centralized services. These results position SURGENT as a practical and trustworthy advancement toward intelligent, equitable, and secure surgical assistance systems.
This paper presents SurgicalRoomAgent, a voice-interactive multi-agent system for smart operating rooms based on large language models (LLMs). The system achieves natural language understanding, device control, intraoperative recording, and surgical report generation through a layered architecture comprising a voice interaction pipeline (wake, ASR, turn detection, agent reasoning, TTS) and an agent core (skill registry, task planner, device manager). Three key technologies are investigated: (1) KV Cache prefix warming for low-latency inference, reducing recomputation overhead from approximately 500 ms to tens of milliseconds via byte-level Longest Common Prefix reuse; (2) streaming partial JSON parsing with early parallel task execution, reducing end-to-end latency by approximately 30%; and (3) progressive skill prompt disclosure, which dynamically filters system prompts based on user role, connected devices, and surgical phase to maximize information density within limited context windows. The system is implemented using the Qwen3-27B model with llama.cpp/sglang inference engines. Experimental analysis demonstrates effective operation within a 16,384-token context limit and multi-device parallel control response times meeting OR real-time requirements.
Fine-grained spatiotemporal reasoning on surgical videos is critical, yet the capabilities of Multi-modal Large Language Models (MLLMs) in this domain remain largely unexplored. To bridge this gap, we introduce SurgCoT, a unified benchmark for evaluating chain-of-thought (CoT) reasoning in MLLMs across 7 surgical specialties and 35 diverse procedures. SurgCoT assesses five core reasoning dimensions: Causal Action Ordering, Cue-Action Alignment, Affordance Mapping, Micro-Transition Localization, and Anomaly Onset Tracking, through a structured CoT framework with an intensive annotation protocol (Question-Option-Knowledge-Clue-Answer), where the Knowledge field provides essential background context and Clue provides definitive spatiotemporal evidence. Evaluation of 10 leading MLLMs shows: 1) commercial models outperform open-source and medical-specialized variants; 2) significant gaps exist in surgical CoT reasoning; 3) SurgCoT enables effective evaluation and enhances progressive spatiotemporal reasoning. SurgCoT provides a reproducible testbed to narrow the gap between MLLM capabilities and clinical reasoning demands. Code: https://github.com/CVI-SZU/SurgCoT.
Surgical scene understanding is a cornerstone of computer-assisted intervention. While recent advances, particularly in surgical image segmentation, have driven progress, real-world clinical applications require a more holistic understanding that jointly captures procedural context, semantic reasoning, and precise visual grounding. However, existing approaches typically address these components in isolation, leading to fragmented representations and limited semantic consistency. To address this limitation, we propose SurgMLLM, a unified surgical scene understanding framework that bridges high-level reasoning and low-level visual grounding within a single model. Given surgical videos, SurgMLLM fine-tunes a multimodal large language model (MLLM) to support structured interpretability reasoning, which is used to jointly model phases, instrument-verb-target (IVT) triplets, and triplet-entity segmentation tokens. These tokens are then temporally aggregated and serve as prompts for a segmentation network, enabling accurate pixel-wise grounding of triplet instruments and targets. The entire framework is trained end-to-end with a unified objective that couples language-based reasoning supervision with visual grounding losses, promoting coherent cross-task learning and clinically consistent scene representations. To facilitate unified evaluation, we introduce CholecT45-Scene, extending CholecT45 dataset with 64,299 frames of pixel-level mask annotations for instruments and targets, aligned with existing triplet labels. Extensive experiments show that SurgMLLM significantly advances surgical scene understanding, improving the primary triplet recognition metric AP_IVT from 40.7% to 46.0% and consistently outperforming prior methods in phase recognition and segmentation. These results highlight the effectiveness of unified reasoning-and-grounding for reliable, context-aware surgical assistance.