An explainable hierarchical self attention-based approach for tremor detection in the time domain

Dynamic Time Warping (DTW) is the dominant approach for measuring similarity between time series, yet standard practice discards the optimal warping path after computing a single distance value, losing local alignment information most relevant to clinical diagnosis. We introduce DiaSeg, a framework that extracts diagonal segments from DTW paths with controlled breaks, characterizing each segment by five geometric features (effective length, interruption count, cost variation, temporal position, and path context), and enabling unsupervised pattern discovery without domain-specific feature engineering. Validated on 91 subjects across six clinical conditions (healthy aging, Parkinson's, Huntington's, ALS, brain tumor, and stroke), three findings emerge. First, diagonal segments form consistent unsupervised patterns (silhouette 0.33) aligned with biomechanical phase annotations, with label-based validation confirming near-perfect separation of healthy and pathological gait (ARI up to 0.986). Second, segments discriminate pathology at 69% (supervised) and 75% (patient-level clustering), with pathology manifesting through distributional shifts in segment length; combining segment and cycle-level features further improves classification to 91.7%. Third, while cycle-based methods achieve higher accuracy (91%), diagonal segments provide phase-specific interpretability unavailable in global representations, localizing where coordination breaks down within the gait cycle. DiaSeg thus transforms DTW from a black-box distance into a source of interpretable temporal features for neurodegenerative disease assessment.

Deep learning models have been increasingly applied to Time Series Forecasting (TSF) in recent years. Transformer-based and MLP-based models have both been used effectively on many real-world TSF regression benchmarks, and there is ongoing debate as to which family of methods is best. While these benchmarks have drawn much attention, it is also worth noting that many current datasets and methods assume approximate periodicity in the time series. In this work, we focus on a new TSF task without periodicity: anticipating falls during humanoid locomotion, on the basis of egocentric vision and proprioception. When the locomotion trajectories are sufficiently diverse, periodicity is violated. We contribute two new benchmark datasets (one from simulation, one from real hardware), showing that periodicity is violated and recent deep TSF methods struggle on these benchmarks. We also propose a novel deep learning architecture that exploits both endogenous and exogenous variables and a training process that rigorously enforces i.i.d sampling of training examples. Our results show statistically significant improvement over prior art in multiple experimental conditions, by 12.73% or more on the real data and 10.40% or more on the simulation data. Code and datasets will be available upon acceptance.

Automatic pain localization, which involves identifying the anatomical origin of pain from peripheral physiological signals without patient self-report, is a clinically critical but largely unaddressed problem, particularly for non-verbal patients. This paper presents a systematic comparison of classical feature engineering and deep sequence learning for subject-independent three-class pain localization using the AI4Pain 2026 Challenge dataset, which comprises four synchronously recorded wearable modalities: electrodermal activity, blood volume pulse, respiration, and peripheral oxygen saturation recorded from 65 participants under controlled TENS-induced pain. A 115-dimensional hand-crafted feature set spanning time-domain, frequency-domain, modality-specific, and cross-modal descriptors is benchmarked against end-to-end deep architectures. Extremely Randomized Trees achieves the highest macro-F1 of 0.539, outperforming the best deep model by 7.4 percentage points, with EDA spectral features emerging as the dominant discriminators. A consistent 26-point gap between pain detection (F1,=,0.815) and localization (F1,=,0.552) across all models points to a fundamental ceiling imposed by the anatomical diffuseness of peripheral autonomic pathways at 10-second resolution.