Large language model (LLM) agents are increasingly applied to long-horizon tasks such as scientific discovery and machine learning engineering (MLE), where sustained self-evolution becomes a key capability. However, existing MLE agents suffer from inter-branch information isolation, memoryless search, and lack of hierarchical control, which together hinder long-horizon optimization. We present MLEvolve, an LLM-based self-evolving multi-agent framework for end-to-end machine learning algorithm discovery. By extending tree search to Progressive MCGS, MLEvolve enables cross-branch information flow through graph-based reference edges and gradually shifts the search from broad exploration to focused exploitation with an entropy-inspired progressive schedule. To allow the agent to evolve with accumulated experience, we introduce Retrospective Memory, which combines a cold-start domain knowledge base with a dynamic global memory for task-specific experience retrieval and reuse. For stable long-horizon iteration, we further decouple strategic planning from code generation with adaptive coding modes. Evaluation on MLE-Bench shows that MLEvolve achieves state-of-the-art performance across multiple dimensions including average medal rate and valid submission rate under a 12-hour budget (half the standard runtime). Moreover, MLEvolve also outperforms specialized algorithm discovery methods including AlphaEvolve on mathematical algorithm optimization tasks, demonstrating strong cross-domain generalization. Our code is available at https://github.com/InternScience/MLEvolve.
Large language model (LLM)-based evolution is a promising approach for open-ended discovery, where progress requires sustained search and knowledge accumulation. Existing methods still rely heavily on fixed heuristics and hard-coded exploration rules, which limit the autonomy of LLM agents. We present CORAL, the first framework for autonomous multi-agent evolution on open-ended problems. CORAL replaces rigid control with long-running agents that explore, reflect, and collaborate through shared persistent memory, asynchronous multi-agent execution, and heartbeat-based interventions. It also provides practical safeguards, including isolated workspaces, evaluator separation, resource management, and agent session and health management. Evaluated on diverse mathematical, algorithmic, and systems optimization tasks, CORAL sets new state-of-the-art results on 10 tasks, achieving 3-10 times higher improvement rates with far fewer evaluations than fixed evolutionary search baselines across tasks. On Anthropic's kernel engineering task, four co-evolving agents improve the best known score from 1363 to 1103 cycles. Mechanistic analyses further show how these gains arise from knowledge reuse and multi-agent exploration and communication. Together, these results suggest that greater agent autonomy and multi-agent evolution can substantially improve open-ended discovery. Code is available at https://github.com/Human-Agent-Society/CORAL.
Long-term memory is essential for LLM agents that operate across multiple sessions, yet existing memory systems treat retrieval infrastructure as fixed: stored content evolves while scoring functions, fusion strategies, and answer-generation policies remain frozen at deployment. We argue that truly adaptive memory requires co-evolution at two levels: the stored knowledge and the retrieval mechanism that queries it. We present EvolveMem, a self-evolving memory architecture that exposes its full retrieval configuration as a structured action space optimized by an LLM-powered diagnosis module. In each evolution round, the module reads per-question failure logs, identifies root causes, and proposes targeted configuration adjustments; a guarded meta-analyzer applies them with automatic revert-on-regression and explore-on-stagnation safeguards. This closed-loop self-evolution realizes an AutoResearch process: the system autonomously conducts iterative research cycles on its own architecture, replacing manual configuration tuning. Starting from a minimal baseline, the process converges autonomously, discovering effective retrieval strategies including entirely new configuration dimensions not present in the original action space. On LoCoMo, EvolveMem outperforms the strongest baseline by 25.7% relative and achieves a 78.0% relative improvement over the minimal baseline. On MemBench, EvolveMem exceeds the strongest baseline by 18.9% relative. Evolved configurations transfer across benchmarks with positive rather than catastrophic transfer, indicating that the self-evolution process captures universal retrieval principles rather than benchmark-specific heuristics. Code is available at https://github.com/aiming-lab/SimpleMem.
Large language models have advanced automated algorithm discovery by synthesizing executable code, but existing frameworks trap them in rigid search pipelines with pre-defined control flows. This limitation restricts adaptive reasoning, blocks cross-paradigm transfer, and discards valuable execution feedback. We propose AlgoEvo, a unified agentic framework that transforms automated algorithm discovery into an interactive, knowledge-accumulating process. An autonomous agent dynamically inspects, diagnoses, and edits code based on runtime feedback. A design skill hub decouples paradigm-specific knowledge from the core discovery engine, allowing a single workflow to seamlessly handle single-objective, multi-objective, and multi-component design. Meanwhile, a hierarchical experience mechanism organizes search trajectories into a task-level tree to guide exploration and consolidates cross-task patterns into reusable skills. Across six representative benchmark tasks, AlgoEvo matches or surpasses specialized methods with substantially fewer evaluations and reduced token consumption, demonstrating strong intra-task accumulation, cross-task transfer, and the ability to reproduce or exceed existing state-of-the-art performance through flexible skill activation.