A Computational Audit of Demographic Association Encoding in ClinicalBERT Language Predictions

Large language models used for clinical diagnostic reasoning are sensitive to sociolinguistic register, not just clinical content. We term this failure mode Narrative Anchoring: identical clinical facts expressed in different registers cause diagnostic outputs to diverge. Unlike prior demographic-bias work, which manipulates explicit identity tokens such as race or income, our benchmark isolates register as the sole channel of variation, with no demographic marker present in any form. We construct a dataset of 1,000 USMLE clinical vignettes, each rewritten into three sociolinguistically distinct personas under an independently audited fact-preservation guarantee, verified by a separate model that never sees the generation prompt. Across seven language models spanning three architecture families and scales, Narrative Anchoring is statistically significant under direct prompting in every model tested, with a Narrative Anchoring Gap of 0.064 to 0.151. Chain-of-thought reasoning and explicit debiasing instructions reduce the bias only partially, and their apparent gains are frequently confounded by accuracy collapse. We introduce NarrativeShield, a three-agent pipeline that structurally extracts and verifies clinical facts before diagnostic reasoning begins, reducing the Narrative Anchoring Gap to near-zero ($-0.004$ to $0.037$) and achieving the lowest rate of severely unstable decisions (DSS $<$ 0.8) of any method across all models, at a modest and mechanistically expected accuracy cost for most models. A stress test using a non-instruction-tuned base model shows that executing a debiasing intervention at all is gated by zero-shot instruction-following ability, not prompt content alone. We release our dataset, human-validated for fact preservation, as a standalone resource for studying register-based clinical bias.

Whether a language model looks demographically biased can depend on how the audit asks its question. A charitable-aid benchmark reports that the same models favor minority applicants when rating requests one at a time and penalize some when ranking side by side. We test whether that reversal generalizes to hiring, lending, and medical triage: 40,726 requests to five models, applications differing only in the applicant's name, and a primary test fixed before collection. It does not. None of 36 planned contrasts survives correction. The rating advantage keeps its sign at roughly half the published size, and a precision extension bounds any hiring ranking penalty below the published effect, though the lending and triage ranking floors sit above that margin, so the exclusion is conclusive for hiring ranking and for rating in all three domains only. Planted disparities tracking their injected sizes and a directional replication on the original aid materials bound these nulls. The audit is livelier than the demographics: models recognize transparent audits nearly always, tie every identical-content comparison whether the varying detail is race or a hobby, and reward first-listed candidates as much as any demographic effect we measure. Audit verdicts reflect audit construction more than demographic bias.

Large language models (LLMs) are increasingly used in clinical settings, raising concerns about racial bias in both generated medical text and clinical reasoning. Existing studies have identified bias in medical LLMs, but many focus on single models and give less attention to mitigation. This study uses the EU AI Act as a governance lens to evaluate five widely used LLMs across two tasks, namely synthetic patient-case generation and differential diagnosis ranking. Using race-stratified epidemiological distributions in the United States and expert differential diagnosis lists as benchmarks, we apply structured prompt templates and a two-part evaluation design to examine implicit and explicit racial bias. All models deviated from observed racial distributions in the synthetic case generation task, with GPT-4.1 showing the smallest overall deviation. In the differential diagnosis task, DeepSeek V3 produced the strongest overall results across the reported metrics. When embedded in an agentic workflow, DeepSeek V3 showed an improvement of 0.0348 in mean p-value, 0.1166 in median p-value, and 0.0949 in mean difference relative to the standalone model, although improvement was not uniform across every metric. These findings support multi-metric bias evaluation for AI systems used in medical settings and suggest that retrieval-based agentic workflows may reduce some forms of explicit bias in benchmarked diagnostic tasks. Detailed prompt templates, experimental datasets, and code pipelines are available on our GitHub.