Organizations: School of Biomedical Engineering, Medical School, Shenzhen University, China · Ultra-X AI Lab, Shenzhen University, Guangdong, China · School of Biomedical Engineering, South-Central Minzu University, Wuhan, China · Department of Radiology, Boston Children’s Hospital and Harvard Medical School, Boston, MA, USA · The Affiliated Hospital of Yunnan University, Kunming, China · Fuwai Shenzhen Hospital, Chinese Academy of Medical Sciences, Shenzhen, China · First Affiliated Hospital of Hebei North University, Zhangjiakou, China
Medical image classification often suffers from class imbalance due to the inherent disparities in disease incidence. Existing approaches, such as class resampling and loss reweighting, mainly improve learning within the observed feature distribution, but do not explicitly enlarge the latent support region of tail classes. As a result, tail-class representations remain overly compact and are easily encroached upon by head classes, leading to biased decision boundaries. In this work, we propose Recurrent Contrastive Learning (RCL) for imbalanced medical image classification. RCL progressively expands the support region of tail classes by recurrently reusing historical feature states across training phases. Specifically, we adopt DINOv3 with LoRA adapters as the backbone to provide robust feature embeddings. We then devise a Temporal Memory Queue (TMQ) to preserve corpus-level features across training phases and provide diversified global references for contrastive learning. Based on TMQ, we construct Temporal Anchors (TARs) to form an anchor field around tail classes. This field enlarges the support region of tail classes, suppresses head-class encroachment, and improves inter-class separation. Extensive experiments on three imbalanced medical datasets demonstrate that RCL achieves consistent improvements over strong baselines. The code is available at https://github.com/dndins/RCL.
The emergence of machine learning and deep learning has revolutionized the efficiency of diagnostic, therapeutic, and administrative systems in healthcare. However, this rapid adoption has come at the cost of requiring significant computing power and energy consumption, as well as e-waste disposal and carbon emissions. One of the challenges of these models is choosing the right model for classification tasks. To this end, researchers attempt to identify the optimal model using their data through trial and error, which involves energy consumption and waste. The goal of this study is to develop a model-based recommender system for medical image classification. For this purpose, a data set was collected from 3,000 articles in the field of medical image classification. This dataset, publicly available under the name MedicalRec-Bench, contains over 5,000 records of models tested in various tasks, including Skin Cancer Classification, Tumour Classification, Wound Classification, Breast Cancer, and MRI classification. The dataset was evaluated in four different modes, depending on the number of features: MedicalRec I (5 features), MedicalRec II (9 features), MedicalRec III (11 features), and MedicalRec IV (18 features). Collecting all values for the features is challenging due to non-reporting by the authors; hence, the dataset contains significant amounts of missing values. The Medical Recommender System (MedicalRec) is a transformer-based model used for item recommendations in this study. This model achieved remarkable results in the evaluation on the dataset and in the evaluation with 12 base models. This model achieved a maximum HitRate@100 of 75.5%. The dataset and implementations are available through the GitHub link: https://github.com/Ramin1Mousa/MedicalRec
Roghayeh Taghavi, Aysa Hasanazde Bashkandi, Amir Ali Bengari +5
Long-tailed class distributions are pervasive in multi-class medical datasets and pose significant challenges for deep learning models which typically underperform on tail classes with limited samples. This limitation is particularly problematic in medical applications, where rare classes often correspond to severe or high-risk diseases and therefore require high diagnostic accuracy. Existing solutions-including specialized architectures, rebalanced loss functions, and handcrafted data augmentation-offer only marginal improvements and struggle to scale due to their limited and largely deterministic variability. To address these challenges, we introduce a diffusion-model-driven synthetic data augmentation pipeline tailored for medical long-tailed classification. Our approach features a novel inpainting diffusion model combined with an Out-of-Distribution (OOD) post-selection mechanism to ensure diverse, realistic, and clinically meaningful synthetic samples. Evaluated on the ISIC2019 skin lesion classification dataset, one of the largest and most imbalanced medical imaging benchmarks, our method yields substantial improvements in overall performance, with particularly pronounced gains on tail classes with more than 28% improvement on the class with the fewest samples. These results demonstrate the effectiveness of diffusion-based augmentation in mitigating long-tail imbalance and enhancing medical classification robustness.
In this paper, we examine the difficulties of using standard techniques for medical image classification due to long-tailed distributions (wherein rarer conditions have very few samples) resulting in bias towards diagnosing common diseases and away from rarer diseases. We then discuss and implement deep learning models with techniques such as augmentation to minimize error, especially from rarer diseases. We evaluate various different models with AP, F1 score, AUROC, and loss (all on the validation set). We conclude with the promising results from our best model, and potential applications in the healthcare space.