cs.AISep 18, 2026

ECG Mirage: Revealing and Mitigating the Underutilisation of ECGs in Vision-Language Models for Clinical Prediction

Authors: Jinning Liang, Mingcheng Zhu, Tingting Zhu

Organizations: University of Oxford, Oxford, United Kingdom

Abstract

Emergency department (ED) decision-making relies on heterogeneous clinical information, including patient history, vital signs, laboratory results, and electrocardiograms (ECGs). Vision--language models (VLMs) can jointly process these modalities, but strong predictive performance does not necessarily imply meaningful use of the correct patient's ECG. We term this failure mode ECG Mirage: apparent multimodal capability without useful dependence on patient-specific ECG information. We distinguish two forms: ECG neglect, where ECGs provide little predictive benefit, and ECG confusion, where matched ECGs outperform no-image inputs but not mismatched ECGs. To evaluate these behaviours, we compare predictions obtained with matched ECGs, outcome-discordant mismatched ECGs, and no-image inputs while holding the clinical text and prediction targets fixed. Across four VLMs on MDS-ED, matched ECGs provide no consistent advantage for either ICU admission or clinical deterioration prediction. We then train four restricted visual prompts using supervised learning followed by conditional direct preference optimisation, while keeping the VLM backbone frozen. The resulting models achieve balanced accuracies of 70.6% for ICU admission and 67.5% for deterioration and increase the matched-versus-mismatched performance gap to approximately 16.5 and 5.5 percentage points, respectively. Overall, our study identifies ECG Mirage in multimodal clinical prediction and introduces visual prompt tuning as an efficient mitigation strategy.

Figures & tables

Explore similar work

CardsList
  1. ECG-Reasoning-Benchmark: A Benchmark for Evaluating Clinical Reasoning Capabilities in ECG Interpretation

    Mar 15, 2026Jungwoo Oh, Hyunseung Chung, Junhee Lee +6Electrocardiogram InterpretationClinical Reasoning

  2. MARCUS: An agentic, multimodal vision-language model for cardiac diagnosis and management

    Mar 23, 2026Jack W O'Sullivan, Mohammad Asadi, Lennart Elbe +10Medical VLMsMultimodal Understanding

  3. Autoregressive EHR Foundation Models with Multimodal Inputs

    Jul 24, 2026Yuxuan Liu, Joshua Placidi, Jinpei Han +3Clinical Outcome PredictionMultimodal Token Compression