Organizations: Beijing Institute of Technology, Beijing 100081, China · Advanced Institute for Ocean Research, Southern University of Science and Technology, Shenzhen, 518055, China · Shenzhen Institute of Advanced Biomedical Robot Company Limited, Shenzhen 518000, Guangdong Province, China · Department of Electronic and Electrical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China · School of Life Science and the Key Laboratory of Convergence Medical Engineering System and Healthcare Technology, Ministry of Industry and Information Technology, Beijing Institute of Technology, Beijing 100081, China · School of Mechanical, Electronic and Control Engineering, Beijing Jiaotong University, Beijing, China · Southern University of Science and Technology, Shenzhen, Guangdong 518055, China · Aerospace Center Hospital and the Key Laboratory of Convergence Medical Engineering System and Healthcare Technology, Beijing Institute of Technology, Beijing 100081, China · Neurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, China
In endovascular interventions, physicians rely on planar DSA and X-ray fluoroscopy to interpret vessel anatomy and device motion, yet converting these images into feedback for autonomous navigation remains difficult. A perception and control method is formulated for two-dimensional image feedback. Vessel masks are converted into a labeled centerline graph, and device-tip estimates are projected onto a planned path to obtain progress, deviation, and direction. A rule-based controller uses these quantities for delivery, branch selection, probing, rollback, and recovery. The method was evaluated on a physical dual-device robotic platform in 65 closed-loop runs using simulator-rendered planar images across three paths. All runs reached at least 0.95 maximum observed guidewire progress; two runs (3.1%) met the prespecified failure rule of three or more autonomous stop events. The results establish route-level performance on the tested platform; clinical image sequences and broader anatomy remain to be evaluated.
Figures & tables
Fig. 1: Overall system and human-in-the-loop workflow. Mentice provides the planar image stream, the physical dual-device robot executes autonomous commands, and the physician supervises and can override the process.
Fig. 2: System architecture and data flow. Offline, custom device and vessel SE U-Net models are trained, exported to ONNX, and converted to TensorRT engines. Online, device masks provide frame-wise tip and direction estimates, whereas the averaged vessel output is locked as a labeled centerline graph. Operator-selected start and target points define the topology-constrained route. Operator-marked interaction-risk points form a separate early-trigger channel: proximity invokes priority retreat before the delayed off-path condition, without modifying the graph or replanning the route. This heuristic response is not a formal safety guarantee. Projection of both tips onto the route produces the visual state used by the priority controller. A discrete command drives the robot and changes the physical device configuration. Mentice updates the device–vessel interaction and renders the realized motion in the next simulator-rendered image, which closes the visual feedback loop.
Metric
Device
Vessel
Train/validation/test images
102/22/22
117/15/14
Output channels
2
11
Training crop
512×512
512×512
Batch size
1
1
Training epochs
60
60
Mean epoch time (s)
28.6
8.6
TABLE I: Segmentation training summary
Task
Backend
Agreement Dice
Patch (ms)
Full frame (ms)
Size (MB)
Device
PyTorch FP32
reference
30.6
70.0
–
Device
TensorRT FP16
0.9999/0.9997
8.1
32.8
60.1
Device
TensorRT INT8
0.9981/0.9854
4.2
17.1
32.1
Vessel
PyTorch FP32
reference
30.8
72.0
–
Vessel
TensorRT FP16
0.9998
8.3
33.5
59.8
Vessel
TensorRT INT8
0.9812/0.9951
4.2
17.9
32.4
TABLE II: TensorRT benchmark
Fig. 3: Capability boundary and evaluated navigation paths. (a) Manual guidewire-only tests define the conditions that can be completed before autonomous testing; the 30 ∘ and J guidewires do not complete Path 3 under the single-guidewire constraint, whereas the corresponding coordinated guidewire–catheter task remains reachable. (b) Simulator-rendered scenes for Paths 1–3 show the operator-selected start and target points and the planned vessel routes. Paths 1 and 2 include five guidewire conditions, while Path 3 includes only the three conditions that passed the prespecified capability check.
Fig. 4: Closed-loop experimental platform. The platform combines the Mentice VIST G7 simulator, physical dual-device intervention robot, controller interfaces, display terminal, and autonomous-navigation workstation. It links device actuation, planar image generation, visual-state estimation, and autonomous commands in one supervised loop; the present dataset contains simulator-rendered projections rather than clinical DSA acquisitions.
Fig. 5: Representative autonomous navigation sequences across the three paths. Each row shows one recorded physical-robot run and follows the same four stages: initial state, autonomous advance, branch probing or recovery, and catheter-follow action. The values below each frame are taken from the synchronized action and state records.
Path
n
Stops/run
Failed runs
Max. wire progress
Cath.-follow trigger
Full duration (s)
Actions
Forward fraction (%)
Path 1
25
0.00±0.00
0/25
1.000±0.000
25/25 (100%)
111.7±37.7
79.9±33.4
76.0±11.6
Path 2
25
0.56±0.87
2/25
1.000±0.000
25/25 (100%)
162.6±75.4
112.1±64.3
71.2±10.6
Path 3
15
0.07±0.26
0/15
1.000±0.000
15/15 (100%)
148.2±34.3
118.8±28.3
66.2±5.0
TABLE III: Run-level outcomes.
Path
Wire IoU
Catheter IoU
Vision time (ms)
Path 1
0.890±0.013
0.949±0.006
70.5±0.9
Path 2
0.882±0.016
0.943±0.012
70.2±0.8
Path 3
0.897±0.013
0.947±0.010
71.1±0.7
TABLE IV: Imaging and timing.
Fig. 6: Autonomous stop counts for individual runs. The dashed line marks the prespecified three-stop failure threshold; crosses identify the two failed runs.
Fig. 7: Mean per-run composition of guidewire advance, catheter advance, backward movement, and turning or rotation across the three paths.
Fig. 8: Complete trial matrices. Panels A–C show full run duration and panels D–F show action count; each cell is one logged repeat. Asterisks mark the two stop-based failures and N/A denotes the excluded Path 3 conditions.
Robotic endovascular intervention uses robotic systems to navigate vascular instruments and perform procedures with greater precision, control, or autonomy.
Department of Control Science and Engineering, College of Electronics and Information Engineering, and Shanghai Institute of Intelligent Science and Technology, Tongji University, Shanghai 200092, China · Department of Electronic Engineering, Faculty of Engineering, The Chinese University of Hong Kong, Hong Kong SAR 999077, China · Shanghai Operation Robot Co., Ltd., Shanghai 201318, China +2
Department of Physiology and Biomedical Engineering, Mayo Clinic, Scottsdale, Arizona, USA · School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, USA
Surgical & Interventional Engineering, School of Biomedical Engineering & Imaging Sciences, King’s College London, UK · Department of Radiology, National Taiwan University Hospital, Taiwan · Department of Neuroradiology, King’s College Hospital, UK