Correspondence Is Not Transfer: A Pairing-Controlled Study of Clinical Audio-Metadata Alignment
Organizations: University of Science and Technology of China, China · Independent Researcher · University of Cambridge, UK
Abstract
Clinical audio models are often trained by aligning recordings with participant metadata or text derived from it. This metadata is rarely a clean disease signal, since a single profile also contains symptoms, age, sex, missing responses, and recruitment information. We examine what alignment adds to frozen audio features by varying only the audio-meta data pairing. We keep the audio backbones fixed and train only a projector under correct pairing and three shuffled conditions that progressively preserve the disease label and recorded sex. We then evaluate each projector on profile retrieval, attribute probing, and disease classification on covariate-matched test sets. On UKCOVID, correct pairing clearly improves retrieval and makes sex easier to decode, confirming that the pairing manipulation works. Most of the sex-probe gap disappears when the control also preserves recorded sex, while a small retrieval gap remains. Matched disease AUROC differences are small, and every interval includes zero, so modest benefits or harms are not ruled out. The same pattern appears when we rerun the frozen pipeline on CODA TB, Cambridge COVID-19 Sounds, and Coswara, where retrieval and sex-probe contrasts are consistently positive but disease contrasts are not. We find no consistent evidence that better profile correspondence translates into better disease prediction and suggest reporting these outcomes separately.
Figures & tables
| Endpoint | Contrast | AST-6L | OPERA | HeAR |
|---|---|---|---|---|
| Sex | 19.1 [16.7,21.5] | 11.2 [9.4,13.1] | 8.6 [7.3,9.9] | |
| [ ,1.5] | 0.7 [ ,1.9] | 0.6 [ ,1.4] | ||
| 19.2 [16.8,21.4] | 10.6 [9.0,12.2] | 8.0 [6.7,9.3] | ||
| Retrieval | 0.3 [0.2,0.5] | 0.3 [0.1,0.5] | 0.7 [0.5,1.0] | |
| 0.2 [0.0,0.3] | 0.1 [ ,0.3] | 0.4 [0.2,0.6] | ||
| Disease | 0.6 [ ,2.8] | [ ,1.7] | 0.3 [ ,1.6] |
Cross-Modal Alignment
Cross-modal alignment maps representations from different data types into compatible spaces so models can compare, transfer, and combine information.
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