Cross-Modal Learning

Computer-aided medical image analysis is crucial for disease diagnosis and treatment planning. While vision-language models (VLMs) such as CLIP exhibit strong generalization ability, their direct application to medical imaging remains hindered by a substantial domain gap. Existing methods for bridging this gap, including prompt learning and unidirectional modality interaction, typically introduce domain knowledge into only one modality. However, such approaches fail to fully exploit CLIP's inherent dual-modality structure and overlook the synergistic effect of bidirectional cross-modal interaction, resulting in persistent modality misalignment. In this paper, we propose NEARL (iNteracted quEry Adaptation with oRthogonaL Regularization), a novel parameter-efficient VLM framework for bidirectional cross-modal interaction. NEARL consists of two key components: (1) the Unified Synergy Embedding Transformer (USEformer), which dynamically generates compact cross-modal queries to facilitate interaction; and (2) the Orthogonal Cross-Attention Adapter (OCA), which decouples new knowledge into truly novel and incremental components through orthogonal regularization. This design reduces interference from incremental components, enabling more focused learning of novel information and improving modality interaction in VLMs. Notably, NEARL introduces only 1.46M learnable parameters. Extensive experiments on three medical imaging modalities demonstrate state-of-the-art performance (e.g., a 2.3% relative improvement on the pneumonia dataset), along with fast inference and low memory overhead, highlighting its effectiveness for real-world medical vision-language understanding.

Multimodal emotion and intent recognition is essential for automated human-computer interaction, It aims to analyze users' speech, text, and visual information to predict their emotions or intent. One of the significant challenges is that missing modalities due to sensor malfunctions or incomplete data. Traditional methods that attempt to reconstruct missing information often suffer from over-coupling and imprecise generation processes, leading to suboptimal outcomes. To address these issues, we introduce an Attention-based Diffusion model for Missing Modalities feature Completion (ADMC). Our framework independently trains feature extraction networks for each modality, preserving their unique characteristics and avoiding over-coupling. The Attention-based Diffusion Network (ADN) generates missing modality features that closely align with authentic multimodal distribution, enhancing performance across all missing-modality scenarios. Moreover, ADN's cross-modal generation offers improved recognition even in full-modality contexts. Our approach achieves state-of-the-art results on the IEMOCAP and MIntRec benchmarks, demonstrating its effectiveness in both missing and complete modality scenarios.

Different machine learning models can represent the same underlying concept in different ways. This variability is particularly valuable for in-the-wild multimodal retrieval, where the objective is to identify the corresponding representation in one modality given another modality as input. This challenge can be effectively framed as a representation alignment problem. For example, given a sentence encoded by a language model, retrieve the most semantically aligned image based on representations produced by an image encoder, or vice versa. To gain insights into the performance impact of different metrics, embedding spaces, and representation alignment for retrieval tasks, we first empirically investigate the geometric relationships between visual and textual embeddings derived from both vision-language models and combined unimodal models. We then align these representations using four standard similarity metrics as well as two learned ones, implemented via neural networks of different architectures with varying losses across multiple benchmarks. Our experimental findings indicate that cosine similarity consistently outperforms all the investigated metrics in representation alignment tasks, and that Wasserstein distance provides a complementary perspective on cross-modal distributional differences. We also observe that our proposed custom contrastive loss is advantageous over the MSE loss for aligning image and text representations, for both multilayer perceptrons and transformer-based models. Taken together, our findings offer novel insights and practical considerations for researchers working in multimodal information retrieval, particularly in real-world, cross-modal applications. Our code is publicly available.

This paper addresses cross-modal medical image segmentation, focusing on MRI-CT transfer in a source-only domain generalization setting. During training, only source-modality samples are available, while unlabeled target-modality images are used for testing. We propose LowBridge, which builds on the observation that cross-modal images share similar low-level features (e.g. edges) as they depict the same types of anatomical structures. Specifically, we first train a generative model to recover the source images from their edge features, followed by training a segmentation model on the generated source images, separately. At test time, edge features from the target images are input to the pretrained generative model to generate source-style target domain images, which are then segmented using the pretrained segmentation network. Experiments on various public datasets demonstrate that LowBridge achieves state-of-the-art performance, outperforming ten existing approaches. Ablation studies further show that LowBridge is compatible with different types of generative and segmentation models, suggesting its generalizability and potential to benefit from future advances in these models. The code will be available at https://github.com/JoshuaLPF/LowBridge.

Conventional forecasting methods are trained end-to-end on unimodal time series, which limits their ability to exploit textual information and undermines their generalization in data-scarce scenarios. Recently, large language models (LLMs) and time series foundation models (TSFMs) have demonstrated powerful capabilities in complex textual reasoning and zero-shot temporal modeling, respectively. Integrating these strengths to construct a multimodal time series foundation model that jointly leverages temporal and textual information for zero-shot future inference has emerged as a promising research direction. However, the scarcity of large-scale, high-quality multimodal datasets remains a fundamental obstacle. To address this challenge, we propose ChronoSteer, a decoupled agentic framework that learns cross-modal alignment from synthetic paired supervision. Specifically, a pretrained LLM first converts textual events into revision instructions that steer the initial unimodal prediction produced by a frozen TSFM. These revision instructions form an intermediate instruction space that bridges the semantic gap between text and time series while fully leveraging pretrained knowledge. Technically, the instructions are discretized into a compact codebook of instruction anchors, effectively mitigating semantic divergence while reducing the cost of dataset construction. Finally, we adopt a two-stage training strategy to recover the fine-grained magnitude information lost during discretization. Furthermore, we release a leakage-controlled multimodal benchmark constructed with temporal separation and textual context available before the prediction window. When paired with an LLM and trained on synthetic cross-modal alignment data, ChronoSteer achieves a 25.8% improvement in zero-shot prediction accuracy over its unimodal backbone, and outperforms prior state-of-the-art unimodal and multimodal ...

Contrastive Language-Image Pre-training (CLIP) demonstrates strong zero-shot generalization, but due to substantial computational and memory costs, distillation into lightweight models is required. Existing relational objectives do not explicitly model multidirectional relationships between teacher and student embeddings, potentially leaving the geometric relationships insufficiently constrained. This may disrupt the modality-gap structure important for zero-shot transfer. To address these limitations, we propose a relational distillation framework, CLIP-RD, which introduces two relational methods, Vertical Relational Distillation (VRD) and Cross Relational Distillation (XRD). VRD aligns teacher-student intra-modal similarity distributions to enforce consistent distillation strength across image and text embeddings. Meanwhile, XRD aligns the teacher-image-student-text and teacher-text-student-image similarity distributions to impose bidirectional cross-modal symmetry. By jointly modeling these multidirectional relational structures, CLIP-RD aligns the student's embedding geometry more faithfully to the teacher's, outperforming CLIP-KD by 1.8%p. This performance improvement is maintained across diverse architectures, teacher scales, retrieval tasks, downstream tasks, and corruption settings, with negligible additional training-time overhead.

End-to-end training of multimodal neural networks often exhibits unstable neural dynamics characterized by three coupled failure modes that degrade learning: (i) modality imbalance, where one branch dominates gradient-based optimization; (ii) unstable gating, where noisy confidence cues induce erratic modality selection; and (iii) fusion interference, where modality-specific gradients conflict at the shared fusion layer. We propose CAT-GS (Calibrated, Adaptive, Thresholded Gating with Fusion Surgery), a neural dynamics-based optimization controller for intelligent computing applications. CAT-GS operates during backpropagation without modifying model architectures, fusion modules, or task losses. Through calibration of teacher-derived reliability via temperature scaling and EMA smoothing, CAT-GS stabilizes neural dynamics using a margin-thresholded policy to switch between warm-up dropout, weak-modality prioritization, and weak-biased blending, stabilizes gradient magnitudes under aggressive gating via capped gradient-budget renormalization, and applies fusion-only PCGrad to reduce destructive cross-modal interference at the primary shared bottleneck. We evaluate CAT-GS on audio--visual multimodal pattern recognition benchmarks (CREMA-D, AV-MNIST, and VGGSound), a tri-modal setting (UR-FUNNY), controlled synthetic data (CG-MNIST), and additional cross-domain benchmarks (AVE and CMU-MOSI). CAT-GS improves or matches fused multimodal accuracy against strong imbalance-aware baselines (including OGM-GE, G$^2$D, and UMT) across settings, and yields smoother gating behavior with fewer conflicting fusion gradients.