Intraoral Scans

Early detection of oral cancer via photographic imaging presents a promising avenue for large-scale oral cavity screening. However, the development of robust deep learning models is frequently hampered by the scarcity of high-quality, annotated datasets. To address this limitation, a novel and well-curated resource, the Photographic Multi-purpose Oral Cancer Imaging (PhotoMOCI) dataset, is introduced for developing models across multiple diagnostic tasks in oral oncology. Then, a comprehensive benchmark study was conducted to investigate how various data augmentation strategies influence the performance of image classifiers. Our analysis spans different generative AI frameworks, evaluating the efficacy of traditional methods against advanced generative approaches, including Generative Adversarial Networks (GANs) and Diffusion Models (DMs). Additionally, we propose the Synthetic Image Filter (SIF), a mechanism to select specific samples based on two auxiliary models: Synthetic Proxy Classifier to ensure samples are representative of the target class and Synthetic Image Detector to verify they appear realistic, thereby selecting only the high-utility images that contribute to improving downstream performance. Across the evaluated datasets and classifiers, the best SIF-filtered setup improves accuracy over traditional augmentation in all cases, with gains of +1.73% and +2.35% on PhotoMOCI and +2.38% and +2.08% on KOCD for ResNet50 and ViT, respectively. Our findings reveal that while the direct application of generative data augmentation may yield performance drops, the integration of SIF, considering (i) how synthetic data looks real and (ii) how it reflects the discriminative features of the belonging class, provides a simple yet effective mechanism to filter out synthetic samples that confuse the classifier during training.

Malocclusion skeletal grading is a fundamental task in orthodontics, critical for diagnosis and treatment planning. Traditionally, cone-beam computed tomography (CBCT) is used for visual measurement, and the reconstructed lateral cephalograms are handed over to expert dentists for diagnosis. However, manual review is time-consuming, labor-intensive, and subject to inter-operator variability. Therefore, an automatic CBCT-based system is needed for reliable malocclusion skeletal grading. In this case, we develop TeethGNN, a novel graph-based framework designed to combine CBCT image features with morphological information for accurate and efficient malocclusion grading. TeethGNN utilizes a decoupled learnable decoder to directly predict key morphological indicators from CBCT images, eliminating the need for manual measurements. These morphological features are then fused with image features using a graph neural network (GNN), which effectively models the relationships between the modalities. To further enhance robustness and calibration, we introduce a collaborative calibration strategy. This strategy combines multi-scale graph adversarial perturbation for explicit calibration and nonlinear topological graph calibration for implicit confidence adjustment. Extensive experiments and ablation studies on our collected clinical dataset demonstrate that our malocclusion measurement system achieves 77.08% in accuracy and 89.61% in AUC, outperforming the compared state-of-the-art methods. These results validate the effectiveness of graph-based multimodal fusion and collaborative calibration in improving malocclusion grading performance. Our system shows strong potential for advancing computer-aided orthodontic diagnosis, providing an accurate and reliable solution for vision-based clinical measurement and diagnosis.

Registration between cone-beam computed tomography (CBCT) and intraoral scans (IOS) is essential for patient-specific surgical planning. However, disparate imaging modalities, limited overlap, and large pose offsets make automated registration unreliable. Consequently, clinical registration remains dependent on conventional geometry pipelines and manual clinician adjustment. To address these challenges, we propose APCReg, an anatomical-prior-guided coarse-to-fine framework for global registration and reliability-controlled residual correction. Specifically, multi-view anatomical coarse registration (MACR) performs ordered orthogonal projection alignment (buccal, proximal, and occlusal) to decompose the six-degree-of-freedom search before three-dimensional refinement. Overlap-aware residual registration (OARR) combines shared KPConv features, a folded arch-length cue, overlap-gated cross-attention, and Sinkhorn matching. Finally, dental-arch-structured hypothesis selection evaluates diverse poses on held-out reliable correspondences, while a ground-truth-free coarse-retention guard conditionally retains a geometrically reliable coarse pose. On 60 held-out jaw pairs, APCReg achieves a submillimeter mean Chamfer distance of 0.87 mm and a Hausdorff distance of 2.92 mm under this evaluation protocol, and ranks first across the six reported metrics among the evaluated open-source baselines.

In digital dentistry and oral surgery, the registration of jawbone CT and intraoral scanner (IOS) data is essential for integrating internal bone structure with high-resolution dental surface geometry. However, this registration is challenging because the two modalities share only a limited region in common, and their true correspondence is generally unknown. This uncertainty has prevented rigorous quantitative evaluation of registration accuracy. In this study, we propose a pseudoIOS evaluation framework in which a point cloud emulating an intraoral scan is generated from CT data within the same coordinate frame, so that the transformation between them is known by construction and can serve as a true ground truth. Using this framework, we propose a coarse-to-fine registration method that combines a domain-generalizable local descriptor (GeDi) for initialization-independent global alignment with the iterative closest point (ICP) algorithm for local refinement, and also evaluate the influence of metal artifacts on registration. In experiments on seven cases, ICP alone frequently converged to local minima from a perturbed initial position, whereas GeDi$+$ICP maintained submillimeter mean absolute error (MAE) across all evaluated jaw and artifact conditions (0.55-0.69 mm). A three-way repeated-measures analysis confirmed that GeDi$+$ICP was significantly more accurate than GeDi alone. Metal artifacts had a statistically detectable overall effect, but their absolute impact on GeDi$+$ICP was small.

Intraoral scanning is widely used for digital optical impressions in prosthodontic, implant, and orthodontic treatment, but full-arch and long-span scanning remain labor-intensive tasks with limited automation. In the confined oral cavity, operators must continuously adjust scanner motion while accumulating narrow field-of-view observations, making reconstruction quality sensitive to missing tooth surfaces and operator workload. We propose RobOralScan, which, to the best of our knowledge, is the first reinforcement learning (RL)-based pipeline for robotic automatic intraoral scanning. RobOralScan introduces a geometric memory-based observation space that accumulates partial scan observations into a tri-state geometric representation, allowing the policy to reason over scan history and insufficiently observed regions. It further introduces tooth-wise coverage learning, combining coverage-aware reward signals and a progressive training scheme to improve global reconstruction coverage while reducing uneven coverage across individual teeth. The learned policy selects relative scanner motions from accumulated geometric memory and robot proprioception for closed-loop scan control within the oral workspace. RobOralScan achieves a Chamfer Distance of 0.00838, an average coverage of 92.58%, a lower-tail per-tooth coverage of 88.45%, and a normalized AUC of 0.6674, completing the scan criterion in 8 of 10 evaluation episodes. Furthermore, zero-shot sim-to-real experiments demonstrate its practical feasibility on a physical robot-scanner setup.

Oral 3D modelling is one of the most essential stages in dentistry, and many different approaches, such as impression taking and intraoral scanning, are commonly used for this phase, each with notable limitations. Impression taking, which involves placing alginate or silicone material in a tray and inserting it into the patient's oral cavity to form a negative mold, suffers from significant patient discomfort, material deformation errors, and difficulties in storage and transportation. Intraoral scanners, which directly scan oral structures in real time using structured light or laser technology, produce state-of-the-art results but are associated with substantially high equipment costs. To address these limitations, this paper proposes a software-based approach that reconstructs a 3D oral model using only ten 2D intraoral images captured from different angles, requiring no dedicated hardware devices. The proposed method reduces cost, eliminates the need for physical scanning equipment, minimises patient discomfort, and enables automated 3D reconstruction. The model is trained on the publicly available Teeth3DS dataset, comprising 950 upper jaw samples, and employs MobileNetV2 as the image encoder combined with Multi-head Attention for multi-view feature fusion. The proposed model achieves an accuracy of 77.49%, measured by nearest-neighbor matching with a distance threshold of 0.035. However, predicted vertices tend to concentrate in high-density regions of the ground truth, resulting in uneven point distribution across the reconstructed model.

Evaluations of dental vision-language models remain fragmented across datasets, task definitions and metrics, and often ignore their computational cost. This limits their widespread deployment for dental screening outside specialist centres, where timely inference, limited hardware, and local handling of patient images are vital for practical, privacy-preserving clinical prescreening. Here we present Pocket-Dentist, an efficiency-aware benchmark for dental multimodal question answering that brings together three datasets spanning approximately 1,159 patients from BRAR and MetaDent, five task types and seven metrics. Across 14 typical VLMs, our results reveal an interesting observation: compact VLMs, such as 2B-parameter models, become competitive with much larger VLMs on most metrics after lightweight adaptation while requiring substantially lower computational costs in dental image understanding. Deployed locally on an iPhone 17 Pro, our finetuned compact VLM Pocket-Dentist-2B processed each sample in 4.31 s, reducing latency by 4.9x and memory use by 2.3x compared with a 7B baseline. Our project page is available at https://2026-icml.github.io/pocket-dentist-icml.

This study developed a computer-aided diagnosis (CAD) system for detecting caries and molar-incisor hypomineralization (MIH) in intraoral photographs. These lesions share similar appearances, making clinical differentiation challenging, especially given their small size and variability in imaging conditions.

Single-unit crown restoration is among the most common procedures in clinical dentistry, with CAD/CAM workflows now designing crowns directly from intraoral scans. Partial scans are often preferred over full-arch scans for single-unit cases due to fewer stitching errors, yet most segmentation networks trained on full arches fail on partial scans, while end-to-end generative crown methods often produce over-smoothed surfaces that lose occlusal detail. We propose an end-to-end pipeline that takes a raw intraoral scan and target FDI tooth number as input and outputs an initial, patient-specific crown proposal for clinician refinement. The pipeline has three phases: (I) data preparation and pose standardization; (II) segmentation routed by scan type; and (III) crown proposal generation via context-aware retrieval and Blender-based fitting. We address partial-scan segmentation through a classify-then-align strategy: a DGCNN classifier categorizes the scan into one of five anatomical types, then coarse-to-fine RANSAC+ICP registration standardizes the jaw coordinate frame, followed by graph-cut optimization to refine tooth-gingival boundaries. Trained on 1,958 partial scans, the pipeline achieves macro-average DSC 0.9249, Recall 0.8919, and Precision 0.9615 across 17 semantic classes; a fine-tuned full-arch model reaches DSC 0.9347. The prepared tooth and its mesial and distal neighbors achieve DSC 0.9468-0.9569 with sub-millimeter Centroid Errors (0.2666-0.2774 mm). These centroids anchor a retrieval module using DGCNN embeddings and cosine similarity over neighboring and opposing teeth, followed by spline-guided alignment and Blender Python API refinement. The pipeline produces a preliminary crown shell in 2.5-3.5 minutes, offering a practical alternative to end-to-end generative approaches.

As dental caries appear as subtle, low-contrast lesions in intraoral imaging, existing deep learning models face significant challenges in the early detection of caries. While recent Transformer-based detectors have shown promising results in natural images, they often fail to capture the domain-specific anatomical priors crucial for dental caries detection. In this paper, we propose Caries-DETR, a specialized Transformer framework for caries detection in intraoral images. A Tooth Structure-aware Query Initialization (TSQI) is designed, leveraging large-scale intraoral photograph pre-training and a structure perception branch (SPB) to integrate high-frequency structural priors, guiding the model to focus on anatomically significant lesion areas. Furthermore, we design a Lesion-aware Dynamic Loss Refinement (LDLR) to implement quality-driven hard mining through adaptive loss reweighting based on lesion size, anatomical relevance, and prediction quality, optimizing detection for subtle lesions. Extensive experiments on two public datasets (i.e., AlphaDent and DentalAI) demonstrate that Caries-DETR achieves a state-of-the-art performance compared to existing methods and exhibits good generalization and robustness. Code and data at https://github.com/XuefenLiu-SZU/Caries-DETR}{https://github.com/XuefenLiu-SZU/Caries-DETR.

Panoramic radiography is a fundamental diagnostic tool in dentistry, offering a comprehensive view of the entire dentition with minimal radiation exposure. However, manual interpretation is time-consuming and prone to errors, especially in high-volume clinical settings. This creates a pressing need for efficient automated solutions. This study presents the first application of YOLOv26 for automated tooth detection, FDI-based numbering, and dental disease segmentation in panoramic radiographs. The DENTEX dataset was preprocessed using Roboflow for format conversion and augmentation, yielding 1,082 images for tooth enumeration and 1,040 images for disease segmentation across four pathology classes. Five YOLOv26-seg variants were trained on Google Colab using transfer learning at a resolution of 800x800. Results demonstrate that the YOLOv26m-seg model achieved the best performance for tooth enumeration, with a precision of 0.976, recall of 0.970, and box mAP50 of 0.976. It outperformed the YOLOv8x baseline by 4.9% in precision and 3.3% in mAP50, while also enabling high-quality mask-level segmentation (mask mAP50 = 0.970). For disease segmentation, the YOLOv26l-seg model attained a box mAP50 of 0.591 and a mask mAP50 of 0.547. Impacted teeth showed the highest per-class average precision (0.943), indicating that visual distinctiveness influences detection performance more than annotation quantity. Overall, these findings demonstrate that YOLOv26-based models offer a robust and accurate framework for automated dental image analysis, with strong potential to enhance diagnostic efficiency and consistency in clinical practice.

Vision-Language Models (VLMs) have demonstrated significant potential in medical image analysis, yet their application in intraoral photography remains largely underexplored due to the lack of fine-grained, annotated datasets and comprehensive benchmarks. To address this, we present MetaDent, a comprehensive resource that includes (1) a novel and large-scale dentistry image dataset collected from clinical, public, and web sources; (2) a semi-structured annotation framework designed to capture the hierarchical and clinically nuanced nature of dental photography; and (3) comprehensive benchmark suites for evaluating state-of-the-art VLMs on clinical image understanding. Our labeling approach combines a high-level image summary with point-by-point, free-text descriptions of abnormalities. This method enables rich, scalable, and task-agnostic representations. We curated 60,669 dental images from diverse sources and annotated a representative subset of 2,588 images using this meta-labeling scheme. Leveraging Large Language Models (LLMs), we derive standardized benchmarks: approximately 15K Visual Question Answering (VQA) pairs and an 18-class multi-label classification dataset, which we validated with human review and error analysis to justify that the LLM-driven transition reliably preserves fidelity and semantic accuracy. We then evaluate state-of-the-art VLMs across VQA, classification, and image captioning tasks. Quantitative results reveal that even the most advanced models struggle with a fine-grained understanding of intraoral scenes, achieving moderate accuracy and producing inconsistent or incomplete descriptions in image captioning. We publicly release our dataset, annotations, and tools to foster reproducible research and accelerate the development of vision-language systems for dental applications.