Multimodal Domain Generalization

Smartphone-based Human Activity Recognition (HAR) models often degrade under distribution shifts caused by changes in users, devices, sensor placements, environments, and acquisition protocols. Domain Generalization (DG) addresses this problem by learning from source domains without access to target data. Existing DG methods span training objectives, representation initialization, and architectural modifications, but these components are typically evaluated in isolation despite operating at different stages of the learning pipeline. We present a large-scale controlled benchmark of DG for smartphone-based HAR, comprising more than 410,000 experiments across four model architectures, thirteen training objectives including Empirical Risk Minimization (ERM), five initialization strategies, four architectural configurations, and two shift scenarios: cross-dataset and cross-position. Results show that individual DG components provide limited and highly conditional gains. Alternative objectives rarely outperform ERM consistently, self-supervised initialization helps in specific settings, and architectural modifications, particularly Dynamic Domain Generalization, provide the clearest standalone improvements. Joint configurations, however, frequently outperform their individual components and exhibit complementary and sometimes super-additive interactions, although gains remain model- and shift-dependent. Class-level analysis shows that the strongest configurations mainly improve difficult, shift-sensitive decision boundaries. Finally, oracle checkpoint analysis reveals substantial unrealized performance: source-validation selection recovers only 53% and 26% of the available oracle gain in cross-dataset and cross-position settings, respectively. Overall, effective HAR domain generalization requires jointly designing DG components and robust model-selection strategies.

Generative data augmentation is widely used to mitigate class imbalance, yet its theoretical effect on downstream generalization remains poorly understood. In this work, we develop a statistical framework for conditional generative augmentation and analyze its impact on classification risk. We formalize augmentation as a distribution-mixing process and show that the resulting risk distortion is controlled by both the augmentation strength and the class-conditional Wasserstein discrepancy between real and generated distributions. We further derive a capacity-dependent generalization bound based on Rademacher complexity, revealing an explicit trade-off between hypothesis complexity, augmentation intensity, and generative fidelity. Empirically, we evaluate the framework on binary and multiclass imbalanced classification tasks using Conditional GAN and Conditional WGAN-GP augmentation. Across datasets, CWGAN-GP consistently achieves lower Wasserstein discrepancies than CGAN, indicating improved distributional fidelity. However, improved fidelity does not necessarily translate into superior classification performance, with classical oversampling methods often remaining competitive. These findings support the central theoretical prediction that augmentation reliability is governed by distributional approximation error rather than predictive performance alone. Overall, this work establishes generative augmentation as a distributional perturbation process whose reliability can be quantified through Wasserstein-based measures and supported by finite-sample generalization guarantees. The proposed framework provides a principled foundation for evaluating synthetic data quality beyond classification accuracy alone.

Hardware shifts, color variations, and changing patient characteristics between development and deployment routinely break trained medical image classifiers. Existing remedies fall short: standard color jittering provides insufficient diversity, while deep generative style transfer algorithms hallucinate features, destroy clinically relevant structures, and waste massive compute resources. To address this, we revisit classical statistical color matching and repurpose it as Colorist, a highly efficient data augmentation strategy that applies global mean-standard deviation matching directly in the RGB color space. We demonstrate that this training-free, fully interpretable approach safely generates structurally intact domain variations, outperforming deep generative models in structural fidelity and color alignment. Across out-of-distribution histopathology, peripheral blood, dermatology, and retinal datasets, it improves balanced accuracy by up to +9% over state-of-the-art domain generalization regularizers and by +13% over an unaugmented baseline. Moreover, by avoiding neural networks in the augmentation loop, Colorist preserves anatomical structure, minimizes carbon footprint, and integrates seamlessly into standard dataloaders. Together, these findings establish statistical matching as a safe, interpretable, yet overlooked alternative to deep architectures for clinical robustness. Source code is available at https://github.com/sdoerrich97/colorist.

Deep neural networks excel in various tasks but struggle to generalize across evolving data distributions, leading to significant performance degradation under domain shifts. Domain incremental learning (DIL) addresses this challenge by enabling models to continuously adapt while retaining prior knowledge. Among existing DIL approaches, the parameter-isolation paradigm achieves state-of-the-art performance. However, these methods often adopt a one-size-fits-all approach to adapt to new domains, resulting in either insufficient learning capacity or redundant parameters. In this work, we propose BPG, a unified framework that addresses both challenges through two complementary components: BPG-Adapter, which dynamically determines each domain's adapter hidden dimension based on domain-specific feature separability, and BPG-Inference, a soft domain mixture strategy that integrates multiple domain-specific models at test time, mitigating domain ID misselection. Experimental results on DomainNet, CDDB, and CORe50 demonstrate that BPG consistently outperforms uniform adapter-based approaches and hard domain selection strategies, achieving state-of-the-art average accuracy while reducing forgetting to as low as 0.22% on DomainNet.

Breast density classification is a critical component of breast cancer risk assessment, yet AI models often struggle to generalize across clinical sites due to vendor-specific acquisition styles. In this work, we introduce two new datasets, BreastMammo and DenseMammo, to facilitate robust multi-view mammography research. We propose a domain generalization framework that utilizes a foreground-only histogram matching protocol to resolve the domain shift issue arising from disparate clinical sources. Internal evaluation using a 5-fold cross-validation protocol demonstrates the efficacy of our approach, with the Swin Transformer backbone achieving a peak AUC of 98.32% for density classification. External evaluation on the TNMammo and LUMINA datasets demonstrates that the proposed approach consistently reduces domain shift, significantly outperforming prominent domain generalization paradigms, including MixStyle and Discrete-Fourier-Transform-based frameworks.

Federated learning enables privacy-preserving collaboration across distributed devices without centralizing local data. However, clients may differ not only in data distributions but also in domain knowledge and annotation capabilities. In this paper, we introduce label granularity skew, a new form of statistical heterogeneity in federated hierarchical classification, in which clients provide taxonomy-consistent labels at different levels of detail within a shared class hierarchy. To model this heterogeneity, we generate client-specific local label hierarchies using a probabilistic relational neighbor classifier and construct a WordNet-guided hierarchy via silhouette score-based coarsening. Our analysis shows that strongly coupled hierarchical models are sensitive to incomplete supervision, while the conditional softmax classifier is more robust. Based on this insight, we propose Branch-wise Decoupled Fine-Tuning (BDFT) and its federated version, FedBDFT, which fine-tune branch-wise classifiers and aggregate them through federated optimization. Experiments on CIFAR-100, TinyImageNet, and ImageNet show that FedBDFT substantially improves robustness under severe label granularity skew, with average gains of 27.9% and 56.4% at skewness levels of 0.6 and 0.9, respectively. Zero-shot results further indicate that FedBDFT better preserves hierarchical representations for unseen fine-grained classes. These findings demonstrate its effectiveness for federated hierarchical classification with heterogeneous label granularities.

Domain generalization (DG) and neural network pruning are conventionally treated as distinct objectives, targeting out-of-distribution (OOD) robustness and model efficiency, respectively. In this work, we bridge this gap by introducing Domain-Aware Pruning (DAP), a framework that leverages network sparsity as a mechanism to implicitly enhance generalization to unseen domains. Diverging from standard binary mask optimization, DAP learns a continuous parameter retention probability $p \in [0, 1]$, framing network compression as a continuous probabilistic masking problem. By introducing a regularization objective that actively penalizes the retention of domain-sensitive weights during the mask training, DAP identifies a domain-invariant subnetwork. Empirical results across five DG benchmark datasets demonstrate that DAP achieves significant sparsity while consistently matching or exceeding the OOD performance of its dense counterparts. Crucially, DAP is an algorithm-agnostic framework that integrates seamlessly with existing DG pipelines without necessitating post-hoc fine-tuning. Beyond efficiency and generalization, we show that DAP natively provides increased robustness to adversarial perturbations and yields highly interpretable models, where the retained weights reliably encapsulate the most domain-invariant and task-critical representations.

High-throughput phenotyping requires AI-enabled computer vision models that generalize across genotypes, locations, and growing seasons, yet such models often lose accuracy under new conditions. Annotating real imagery for every genotype-by-environment (G x E) combination a breeding program encounters is prohibitively expensive. We quantify how G x E shifts affect AI-based detection of cowpea flowers and pods across two California locations and two growing seasons. Flower detection mAP@50 fell from 76.3% to as low as 50.6% under unseen shifts, and pod detection was more sensitive. Feature-space and image-quality diagnostics confirmed these losses track measurable distributional shifts. Because closing this gap with real data alone is not practical, we test whether synthetic imagery, rendered from a procedural 3D cowpea model, can substitute for that annotation burden. Synthetic supervision alone improved over pretraining but remained limited by a domain gap driven by camera image formation, not scene content. A domain-gap-aware camera-realism augmentation strategy, optimized against measured real-image statistics via Wasserstein distance, narrowed this gap, and a linear HDR representation converted a smaller measured gap into a larger detection gain than an 8-bit representation. Optimized HDR synthetic data combined with as few as five real images matched or exceeded the real-data baseline for spatial generalization, and pod detection benefited most at the lowest shot counts, with more modest gains under temporal shift. These results show that synthetic data can overcome the generalization limits of AI-based flower and pod detection, but only when the domain gap is measured and optimized rather than assumed away.

Domain generalization (DG) aims to learn from multiple source domains and generalize to unseen target domains. Most DG methods pursue invariance: they seek a causal representation whose prediction rule is invariant across domains. This principle is effective when the causal mechanism is stable, but becomes restrictive when the domain itself modulates how causal content maps to the response. In this case, directly feeding domain style into the predictor can create misleading shortcuts, since style does not by itself cause the response. Yet the apparent chaos of multiple styles can become a ladder: style can locate the unseen target domain among source domains and guide which domain-dependent prediction rules should be trusted. We propose \emph{Latent Adaptive Domain Disentanglement and Environment Reweighting} (LADDER), a fixed-model DG pipeline that learns causal/style representations, freezes the encoders, fits source-specific classifiers, and uses an unlabeled target-domain covariate set only at inference to compute weights over these fixed classifiers, with no target labels or model-state updates. We establish theoretical guarantees for source reweighting and validate LADDER on simulations, FMoW, and a location-grouped iWildCam protocol, with gains in overall and group-averaged accuracy.

Automatic depression detection with deep learning has shown promise but often suffers from limited generalization due to domain shift arising from inter-speaker variability. To address this critical issue, we present the first patient-independent multimodal depression detection framework that incorporates domain generalization (DG), jointly leveraging both acoustic and textual modalities. The proposed model integrates bidirectional Long Short-Term Memory (BiLSTM) with intra- and cross-modal attention mechanisms, accompanied by segment-level fusion for decision-making. Generalization is further enhanced by applying a gradient reversal layer inspired by Domain-Adversarial Training of Neural Networks (DANN), which promotes domain-invariant representations by adversarially limiting the model's ability to identify individual speakers, effectively reducing patient-specific bias. Conducting experiments on the Androids-Corpus dataset with a 5-fold cross-validation (CV) protocol, various pairings of audio and text feature extractors were evaluated over different segment durations, determining MelSpec and ItalianBERT as the optimal baseline at a 30-second segment duration. The addition of DG to this baseline yields a 2.5% increase in accuracy and 3.3% in F1-score, achieving 93.2% accuracy, 93.2% precision, 96.2% recall, and 94.2% F1-score, surpassing all existing benchmarks. Extensive ablation studies assess the impact of multimodal fusion, deep architectural choices, and DG, highlighting their combined contribution to robust and generalizable depression detection.

Domain Generalization (DG) aims to learn representations robust to distribution shifts. Recent geometric alignment methods, such as CPCANet, extract domain-invariant structures through batch-wise Common Principal Component Analysis (CPCA). However, CPCANet suffers from rank-deficient covariance estimation due to the small-sample-size issue in mini-batch training. To address this limitation, we propose Projection Pursuit CPCANet (PP-CPCANet), a covariance-free framework that learns a global orthogonal basis on the Stiefel manifold and jointly optimizes it with network parameters via the Cayley transform. We further introduce a symmetry-breaking detached-median PP dispersion objective to extract common principal components (CPCs) with dense and robust optimization signals. Experiments on four DG benchmarks show that PP-CPCANet achieves SOTA performance while maintaining stable training.

Modern vision-language models (VLMs) have significantly improved image generation and editing capabilities, making pixel-level image tampering detection increasingly important yet challenging under cross-model and out-of-distribution shifts. This work studies domain generalization for pixel-level image tampering detection in modern VLMs like ChatGPT, Gemini, Qwen-Image, etc., aiming to learn tampering localization models that remain robust across diverse VLM-generated manipulation distributions. We propose a simple yet effective domain-generalized training framework built on two practical strategies. First, we introduce a balanced minibatch sampling scheme that strategically samples tampered and real images in each minibatch, preventing biased optimization toward either manipulated artifacts or clean-image priors and avoiding training collapse, ensuring that each optimization step receives proper sampled gradient signals. Second, we adopt a simple late-injection strategy, where the detector is first trained on large-scale base data until stable convergence, and then exposed to a small amount of newly selected supporting data from emerging VLM distributions, improving adaptability without overfitting to limited new domains. Together, these components provide a simple yet strong recipe for improving pixel-level tampering localization and OOD robustness across modern VLMs. Despite the conceptual simplicity, our framework outperforms the prior state-of-the-art PIXAR by a large margin of 26.1% and 26.8% relative improvement in average gIoU and cIoU, respectively, across OOD VLMs of GPT-Images-2.0, Gemini-3.1, FLUX.2, and Seedream 4.5. Our code is available at https://github.com/VILA-Lab/PIXAR-DG

We study hierarchical domain generalization as a problem of extrapolation from finite observed regions to an entire instance space, replacing i.i.d. sampling with arbitrary domain hierarchies. We show that the central obstruction is not only the complexity of the hypothesis class, but the train/test domain partition through which evidence is revealed. In particular, no matter how small the class or how large the training size, some partition makes generalization fail for some target. These results suggest that modern generalization theory must treat domain structure as a first-class object.

Multi-label classification assigns several co-occurring labels to each aerial scene, yet deployed models often encounter data distributions different from their training. Feature-statistics augmentation such as MixStyle, EFDMix, and correlated style uncertainty improves generalization at low cost but perturbs channel statistics globally, treating each image as a single style; one class can then contaminate the augmentation of another. Domain generalization is understudied for multi-label remote sensing; no prior method or multi-source benchmark targets it. A label-decoupled augmentation framework is therefore proposed, confining style perturbation to label-specific regions. Per-label attention, obtained from a learnable module or from gradient class-activation maps, yields per-label feature statistics; these statistics are mixed with cross-domain samples that share present labels, under independent per-label coefficients, and features are recomposed by attention-weighted normalization. Three operators combined with two attention sources produce six variants, evaluated on a leave-one-domain-out benchmark from multi-label UCM, AID, and DFC15 over six shared labels. Averaged over three splits and five seeds, the best variant attains 71.5% mean average precision, exceeding empirical risk minimization by 5.0 points and the strongest global-statistics baseline by 1.3 points, with the largest gain on the hardest transfer (up to 7.7 points). Ablations indicate that spatial attention and refreshed localization maps are most influential. The framework adds at most 0.35% parameters, leaves inference unchanged, and appears to offer a generic, inexpensive upgrade path for multi-label statistics-based domain generalization. Code is available upon acceptance at https://github.com/Alaa-Almouradi/Style-Augmentation-Upgrade.

Through-the-wall radar (TWR) human activity recognition (HAR) is important for non-line-of-sight indoor sensing, security monitoring, and emergency rescue. However, structured distribution shifts caused by person variation, observation-view variation, and wall-condition variation severely degrade recognition generalization, while the origin of the target-domain error still lacks a rigorous theoretical explanation. To address this issue, a generalization-analysis framework for TWR HAR is proposed in this paper. First, models for indoor human kinematics, TWR echo generation, radar image formation, feature representation, and bounded-weight neural networks are established within a unified source-to-target learning formulation. Then, the source risk, target risk, empirical risk, and admissible physical domain descriptor are defined, and a unified target-domain generalization bound is derived. Next, the structured shift term is decomposed into cross-person, cross-view, and cross-wall components, and the bound-tightening effects of physical low-dimensional representations, multi-source training, and parameter-space coverage are analyzed. Simulated and measured experiments jointly support the resulting theoretical analysis and illustrate its application value.

In this paper, we study Single-Domain Generalized Object Detection (Single-DGOD), which aims to transfer a detector trained on a single source domain to multiple unseen domains. Existing methods mainly rely on simulation-driven strategies, such as data augmentation or textual prompts, to enlarge the training distribution. However, finite simulations can hardly cover the dynamic variations of real-world scenarios, often causing overfitting to synthetic styles and limited robustness to complex structural degradations. Inspired by the manifold hypothesis, we argue that semantic features, despite diverse visual changes, should lie on a compact and stable low-dimensional manifold. Therefore, robust generalization requires rectifying deviant samples back to this semantic manifold, rather than exhaustively simulating external perturbations. To this end, we propose Manifold Regression with Visual-Text Dual Chain-of-Thought (MR-DCoT), which formulates unknown-domain generalization as a manifold regression problem. MR-DCoT first uses a Visual-Text Dual Chain-of-Thought module to combine VLM-guided semantic evolution with diffusion-based structural perturbation, generating structured off-manifold hard examples. It then introduces Class-Specific Prototype Anchoring to learn a rectification operator that projects deviant features toward the source semantic manifold. By integrating outlier generation and semantic correction into a closed loop, MR-DCoT effectively narrows the distribution gap and improves robustness under unseen shifts. Extensive experiments on three complementary benchmarks, including adverse-weather detection, real-to-art generalization, and zero-shot semantic segmentation, demonstrate the effectiveness and versatility of our method.

Generalizing sleep staging models to unseen datasets is challenging, and typical domain generalization (DG) methods often rely on multiple source domains or domain labels that are rarely available in practice. We tackle the stricter and more practical setting of single-source domain generalization: training on a single labeled source dataset, without domain labels or access to target data. We present SleepBand, a physiology-guided framework that embeds oscillatory priors via a learnable Morlet filter bank and a structured integration-and-recalibration pipeline. This anchors representations to domain-invariant sleep rhythms (e.g., slow waves, spindles), reducing reliance on dataset-specific artefacts. On five public datasets, SleepBand achieves state-of-the-art SDG performance and remains competitive under leave-one-domain-out (multi-source) DG. Analyses show that the learned filters align with canonical neurophysiology and that robustness stems from focusing on narrowband, physiologically meaningful cues. Our results suggest that principled, physiology-aware inductive biases are a promising path for robust single-domain sleep staging. Code is available at https://github.com/lzcn/sleep-band

Intelligent industrial maintenance critically relies on reliable fault diagnosis of rotating machinery. However, it faces formidable challenges from unknown fault types and domain shifts induced by varying operating conditions, which is formally formulated as the open-set domain generalization (OSDG) problem. Existing methods are mainly data-driven, thereby overlooking the cascaded propagation of uncertainty across feature extraction, topological learning, and decision-making stages.To tackle this challenge, we propose PGU-OD, a novel Physics-Informed Graph Learning framework with Uncertainty Awareness for Open-set Domain generalization. First, it designs a physics-informed spectral attention module to extract condition-robust fault features, thereby suppressing perceptual uncertainty caused by frequency shifts. Further, it constructs an uncertainty aware adaptive graph learning mechanism to dynamically adjust the edge weights of the sample graph guided by class-scale Gaussian distribution parameters, which mitigates the structural propagation of uncertainty. Finally, a Gaussian-distribution-based adaptive boundary loss function and a dual-criteria open-set inference strategy are developed to optimize decision boundaries and reliably reject unknown faults. Extensive experimental evaluations on two public and widely used rotating machinery fault datasets demonstrate that the proposed PGU-OD outperforms state-of-the-art baselines in both known fault classification and unknown fault rejection under domain shifts.

Visual recognition models often fail when deployed in new environments. Domain Generalization (DG) addresses this by learning representations that remain invariant to environment-specific variations. Recent approaches increasingly rely on large vision-language models, assuming that preserving their expressive visual representations improves robustness. However, we show that such visual expressiveness can instead propagate spurious cues that tie representations to the training environments, hindering invariant learning. We therefore discard visual guidance and instead treat the language embedding space as the primary source of domain invariance, naturally acting as an information bottleneck that preserves core semantics while suppressing domain-specific variations. Extensive experiments across diverse backbones exhibit state-of-the-art performance and further analyze what makes guidance effective for robust generalization. These findings shift the focus of DG from improving representations to designing supervision that enforces invariance.

Domain generalization (DG) aims to learn a model from one or more source domains that generalizes to an unseen target domain without accessing target data during training. A common approach enforces invariance of representations across all source domains, assuming predictive structure is globally shared. However, we demonstrate that enforcing invariance across more domains gradually restricts the feasible representation space, discarding transferable predictive factors that are not universally shared. To address this limitation, we propose subset-shared invariance, where predictive structure is assumed stable only within domain subsets. We implement this principle with a mixture-of-experts architecture, where each expert aligns the specific domains it serves and a routing mechanism composes subset-invariant components for prediction. This creates a routing-conditioned invariance, jointly learned with the representation. To facilitate effective decomposition, we develop training objectives that encourage selective alignment, confident and balanced routing, and diverse expert specialization. Experiments on DomainBed benchmarks demonstrate improved out-of-domain generalization and greater robustness under increasing domain heterogeneity. Our results suggest that DG should move beyond enforcing a single global invariance and instead model invariance through partially shared structure across domain subsets.

Domain generalization learns from multiple source domains to generalize to unseen target domains. However, it often neglects the realistic case of label mismatch between source and target. Open set domain generalization is then proposed to recognize unseen classes in unseen domains. A simple approach trains one-vs-all classifiers to separate each class and detect outliers as unknown. Yet, the imbalance between few positive samples and many negative samples skews the decision boundary towards the positive ones, leading the model to over-reject out-of-distribution data, even from known classes in unseen domains. In this paper, we propose a novel meta-learning stategy called dualistic MEta-learning with joint DomaIn-Class matching (MEDIC), which considers implicit gradient matching towards inter-domain and inter-class task splits simultaneously to find optimal boundaries balanced for both domains and classes. Experimental results show that MEDIC not only outperforms prior methods in open set scenarios, but also maintains competitive close set generalization ability.

Single domain generalization (SDG) aims to learn a robust model, which could perform well on many unseen domains while there is only one single domain available for training. One of the promising directions for achieving single-domain generalization is to generate out-of-domain (OOD) training data through data augmentation or image generation. Given the rapid advancements in AI-generated content (AIGC), this paper is the first to propose leveraging powerful pre-trained text-to-image (T2I) foundation models to create the training data. However, manually designing textual prompts to generate images for all possible domains is often impractical, and some domain characteristics may be too abstract to describe with words. To address these challenges, we propose a novel Progressive Adversarial Prompt Tuning (PAPT) framework for pre-trained diffusion models. Instead of relying on static textual domains, our approach learns two sets of abstract prompts as conditions for the diffusion model: one that captures domain-invariant category information and another that models domain-specific styles. This adversarial learning mechanism enables the T2I model to generate images in various domain styles while preserving key categorical features. Extensive experiments demonstrate the effectiveness of the proposed method, achieving superior performances to state-of-the-art single-domain generalization approaches.

Generalized Category Discovery (GCD) aims to classify old categories and discover new ones from unlabeled data. Recent multi-modal approaches introduce retrieved or synthesized texts into a dual-branch architecture to provide semantic cues complementary to visual features. However, the cross-modal synergy in existing dual-branch methods remains coarse and incomplete: the two modalities are encoded independently with the bias and noise in the derived text left unaddressed during encoding, and existing mutual learning strategies operate only on global class-level anchors, lacking fine-grained relational supervision. To address these limitations, we propose the Synergistic Dual-Branch Adaptation (SDBA) framework, which serves as a plug-and-play enhancement compatible with existing dual-branch methods such as GET and TextGCD. SDBA comprises two components: the cross-modal synergistic adapter inserts lightweight adapters into both branches and further injects visual information into the text adapter at each encoder layer to enhance text feature learning during encoding; the neighborhood mutual learning module enforces consistent local neighborhood distributions between the two branches via bidirectional KL divergence, providing fine-grained relational supervision for both old and new classes. Extensive experiments on six benchmarks demonstrate state-of-the-art performance, and consistent improvements on different baselines validate the broad scalability of the proposed framework.

Domain adaptation remains a central challenge in 3D vision, especially for multimodal foundation models that align 3D point clouds with visual and textual data. While these models demonstrate strong general capabilities, adapting them to downstream domains with limited data often leads to overfitting and catastrophic forgetting. To address this, we introduce ReFine3D, a regularized fine-tuning framework designed for domain-generalizable tuning of 3D large multimodal models (LMMs). ReFine3D combines selective layer tuning with two targeted regularization strategies: multi-view consistency across augmented point clouds and text diversity through synonym-based prompts generated by large language models. Additionally, we incorporate point-rendered vision supervision and a test-time augmentation mechanism with confidence-based aggregation to further enhance robustness. Extensive experiments across different 3D domain generalization benchmarks show that ReFine3D improves base-to-novel class generalization by 1.36%, cross-dataset transfer by 2.43%, robustness to corruption by 1.80%, and few-shot accuracy by up to 3.11%, outperforming prior state-of-the-art methods with minimal added computational overhead.

Industrial anomaly detection suffers from limited data, making cross-domain generalization particularly challenging. Generalist Anomaly Detection (GAD) aims to train a unified model on a source domain that can effectively detect anomalies in unseen target domains. In the initial semantic feature space, strong entanglement between anomalies and object categories or defect types hinders effective generalization across domains. Recent works address this issue by projecting features into a residual space; however, such methods primarily increase cross-domain overlap for normal features, while anomalous features remain specific to object categories, defect types and data domains, leading to poor alignment and generalization. To address this limitation, we propose Value-order Decomposition (VOD), a simple yet effective technique that bridges \textbf{three types of generalization gaps} across object categories, defect types (including real and synthetic defects), and data domains. VOD disentangles and suppresses object-category-, defect-type-, and domain-specific information, promoting alignment within normal and abnormal samples while preserving their separability, thereby enabling robust generalization across the three gaps. Leveraging the strong alignment between real and synthetic defects within the same object, we perform anomaly detection using only normal and synthetic-abnormal reference, and effectively generalize to unseen real defect types. Experiments on diverse industrial and medical benchmarks demonstrate that our method, using a simple cut-and-paste anomaly simulation strategy, achieves strong generalization across the three gaps.

Deepfakes are artificially generated images, audio, or videos that threaten privacy, security, and information integrity. Detecting such content is crucial for countering disinformation, as the latest models generate highly realistic content. While spatial- or frequency-based approaches achieve good detection rates on Generative Adversarial Networks (GANs)-based generated deepfakes, they often struggle with recent diffusion model-generated images. In particular, existing approaches rarely exploit complementary multi-domain representations or systematically evaluate cross-generator robustness. To address these challenges, we propose a multi-domain deepfake detection framework called SGFF-Net (Spatial-Gradient-Frequency Fusion Network) that integrates spatial, gradient, and DWT (Discrete Wavelet Transform)-based frequency representations within a dual residual learning architecture. Experimental results show that the SGFF-Net achieves 98.95% accuracy in intra-dataset evaluation and improves performance in both cross-model (70.46%) and cross-paradigm (69.94%) settings. Incorporating multi-source training and data augmentation further enhances robustness, increasing accuracy from 70.46% to 79.80% in cross-model evaluation, from 69% to 78% in cross-paradigm evaluation, and from 61.50% to 75.80% on real-world data. Unlike single-domain detectors, the SGFF-Net learns complementary forensic cues across spatial, gradient, and wavelet-frequency domains, resulting in greater robustness under cross-generator and cross-paradigm evaluation. The results further show that combining multi-domain representations with data diversity and augmentation substantially improves generalization, providing practical insights for developing more reliable deepfake detection systems.

Machine learning models often degrade when they are deployed on a target distribution that differs from the source distributions they were trained on. Recent work in causality-based domain generalization has shown how shared causal structure between domains can induce invariant predictors, e.g., models on a subset of features which have stable risk across structured domain shifts. However, the extent to which such population-level causal invariances can lead to gains in finite-sample settings remains underexplored. In particular, in practice we often have access to a few labeled target samples, a setting called supervised domain adaptation (sDA). In this paper, we explore when (full or partial) causal knowledge can provably improve supervised domain adaptation. As a first step, we study linear regression, where full or partial causal knowledge specifies a collection of invariant or possibly invariant feature subsets, each yielding a source-trained candidate predictor. We derive matching upper and lower bounds showing that finite-sample gains are governed by the target-risk margins separating the candidates, together with the finite-source estimation error. When these margins are sufficiently large relative to $n_Q$, an adaptive aggregation procedure can match the best candidate predictor while avoiding negative transfer relative to target-only learning. On the other hand, when the margins are too small, no algorithm can reliably exploit the candidate collection to obtain faster finite-sample rates. We further connect these margins to structural shift magnitude in linear SCMs and validate the theory on real-world causal benchmarks.

In real-world deployment under strict real-time constraints, weather and imaging variations induce significant distribution shifts, severely degrading detectors. Single-Domain Generalized Object Detection aims to mitigate this issue, yet existing methods rarely investigate-at the level of problem formulation-the generalization capability of real-time detectors under such constrained inference budgets. To this end, we introduce Real-Time Single-Domain Generalized Object Detection (RT-SDGOD), which focuses on how real-time detectors can achieve cross-domain generalization under zero extra inference overhead by relying solely on training-time representation learning. We observe that, under domain shift, DETR-based real-time detectors mainly degrade through increased missed detections, rooted in limited and unstable object-level discriminative evidence. Based on this, we propose RT-SDGDet, a multi-evidence collaborative modeling framework for RT-SDGOD. The core idea is to enable multiple queries of the same object to collaboratively cover more sufficient discriminative evidence while maintaining the stability of such evidence modeling across views. Specifically, we use one-to-many (O2M) supervision to construct stable object-specific query groups, and further design Discriminative Evidence Diversity Learning (DEDL) and Dual-view Evidence Consistency Learning (DvECL) to expand object-level evidence coverage and improve evidence stability under appearance perturbations, respectively. Since all components are introduced only during training, our method incurs no extra inference overhead. Extensive experiments show that the proposed method achieves better generalization performance than existing approaches across multiple unseen target domains.

Open-domain open-vocabulary detection (ODOVD) requires detectors to generalize to both novel categories and unseen domains, making it more challenging than open-vocabulary detection. Existing methods typically train open-vocabulary detectors together with domain generalization modules from scratch, leading to high training cost. we propose ExDet, a lightweight category-domain collaborative generalization framework for ODOVD that enhances the cross-category and cross-domain generalization of existing detectors. ExDet consists of Text-Guided Extrapolation (TGE), a lightweight Detector-Compatible Rectification (DCR) module, and ExRPN. Specifically, TGE exploits the DeltaSpace property of vision-language models (VLMs) to infer category- and domain-aware proxy visual prototypes from text. DCR is learned from the TGE-generated prototypes in a detector training-free and real-data-free manner, and is inserted after the classification head at inference to rectify representations toward a detector-compatible source-domain visual distribution, thereby enhancing classification for targets from novel categories and unseen domains. ExRPN recalibrates proposal scores by combining semantic similarity with RPN confidence, improving recall for novel and domain-shifted objects while providing better support for subsequent classification and DCR. ExDet achieves SOTA performance on OD-LVIS, OV-LVIS, Objects365, and MSOSB.

Multi-modal Domain Generalization (MMDG) seeks to leverage complementary modalities to enhance model robustness on unseen domains. Despite extensive progress in Multi-modal Learning (MML) and Domain Generalization (DG) as individual fields, their systematic integration remains under-explored. Current MMDG research is largely confined to action recognition and lacks standardized evaluation protocols. To address this, we introduce MMDG-Bench, a comprehensive benchmark featuring two foundational frameworks: DG then MML (D2M) and MML then DG (M2D). We provide unified experimental protocols across diverse tasks, including video-audio-flow action recognition and RGB-Depth-IR face anti-spoofing. By instantiating ten MMDG baselines through pairing a unified MML configuration with five DG techniques under both D2M and M2D orderings, we demonstrate that these structured combinations frequently outperform existing state-of-the-art methods, underscoring the necessity of a unified benchmarking effort. Our analysis yields three key insights: (1) Integrating DG techniques provides consistent generalization gains across various backbones, whereas non-DG methods are highly sensitive to backbone shifts; (2) The optimal framework choice depends on inter-modal stability: D2M excels when modal relations are stable across domains, while M2D is more robust to cross-domain relational variance; (3) Stronger backbones yield amplified performance dividends when integrated into our structured frameworks. MMDG-Bench provides a principled foundation and actionable design guidelines for future research in multi-modal robustness. Code is released at https://github.com/qszhan/MMDG-Bench.

AI-driven respiratory sound classification (RSC) is promising for automated pulmonary disease detection, yet multi-site deployment is hindered by inter-stethoscope variability. We introduce a federated domain generalization (FedDG) formulation for RSC in which clients hold recordings from different stethoscopes and the model is evaluated on an unseen device. Our empirical analysis shows that stethoscope-induced style and disease-relevant content are partially entangled, making deterministic style removal unreliable. In response, we propose BTS-CAFE, a framework combining (i) causality-inspired device-style interventions with constraints designed to limit content distortion, (ii) counterfactual metadata augmentation to relieve device and demographic shortcuts, and (iii) gradient alignment to promote device-invariant decision boundaries across clients. Built on BTS with CLAP, a multimodal language-audio pretraining model, BTS-CAFE improves the out-of-distribution ICBHI Score by 3.69 points on average over five held-out devices relative to its backbone, and outperforms conventional data augmentation and federated learning baselines in simulated device leave-out evaluations on the ICBHI and SPRSound datasets.

Scribble-guided image editing allows users to combine simple scribble annotations with text prompts to specify both where and how an image should be edited, enabling flexible interaction with precise spatial control. However, existing models still exhibit unstable performance under this paradigm, especially in multi-task scenarios. To improve performance, we conduct empirical studies using an open-source editing model and reveal an asymmetry in generalization: instruction-level generalization, including across editing tasks and from single-task to multi-task settings, is more challenging than image-domain generalization, such as from synthetic to real-world images or from mosaicked to regular images. This suggests that the primary bottleneck lies in insufficient learning for diverse editing instructions rather than in the image domain gap. Motivated by this insight, we propose three strategies: (a) a Coverage-then-Realism Curriculum, a two-stage pipeline that first builds large-scale synthetic, instruction-rich data for broad task supervision, then curates a small set of real-world data to refine generation realism; (b) Multi-Task Mosaicking, which constructs multi-task training samples by concatenating single-task examples at nearly zero cost while enabling the learned capability to generalize to non-mosaicked images; and (c) an Edit-Focused Loss, which leverages the changed regions between input and output images in synthetic data to focus training on edited regions, improving both learning efficiency and editing accuracy. With these strategies, we substantially improve both single-task and multi-task scribble-guided editing on the VIBE benchmark, achieving state-of-the-art results. We will publicly release our dataset and model.

Data streams in real-world industrial scenarios often contain transitional operating conditions that are uncovered during offline training, leading to significant distribution shifts. To bridge the gap between static offline models and dynamic online data, a novel asymmetric adaptation-based fault diagnosis method is proposed in this paper. Specifically, in the offline stage, we employ domain generalization techniques to extract domain-invariant features from multiple stable conditions and construct robust normalized fault prototypes as reference anchors. Subsequently, during online inference, we design an online test-time adaptation method based on a periodic prototype re-projection mechanism to dynamically update prototype positions. Furthermore, we utilize the geometric distribution derived from anchors to guide the updates of classifiers and adopt an asymmetric learning rate strategy for the feature extractor and classifier. The proposed approach ensures rapid adaptation to new transitional conditions while preserving the discriminative power inherited from the offline domain generalization initialization. Experimental results demonstrate that this mechanism effectively leverages offline generalized knowledge to guide online inference, significantly improving robustness in non-stationary environments.

Robust whole-slide image (WSI) analysis under strict data-governance remains challenging due to substantial cross-institutional stain heterogeneity. Domain generalization (DG) mitigates these shifts but typically requires centralized data, conflicting with privacy regulations. Federated learning (FedL) provides a decentralized alternative; however, existing FedL and federated DG (FedDG) approaches rely almost exclusively on low-order statistics, assuming Gaussian-like stain distributions. In contrast, real-world staining processes often produce asymmetric, heavy-tailed color distributions due to biochemical diffusion and scanner nonlinearity. Consequently, current methods fail to model the higher-order, non-Gaussian characteristics dominating real-world stain variability. To address this, we propose FedStain, a stain-aware FedDG framework explicitly incorporating higher-order stain moments--skewness and kurtosis--as compact statistical descriptors exchanged during federated optimization. These descriptors require no pixel-level data transmission, preserving strict privacy and communication efficiency, while enabling the global model to capture stain variability missed by low-order statistics. FedStain also employs a contrastive, cross-site parameter aggregation strategy to promote stain-invariant representations without relaxing data constraints. Extensive experiments on Camelyon17 and our new MvMidog-Fed benchmark show FedStain yields consistent improvements, outperforming state-of-the-art FedL, DG, and FedDG baselines by up to +3.9% absolute accuracy. To our knowledge, FedStain is the first FedDG approach to explicitly model higher-order stain statistics, enabling robust cross-institutional deployment in computational pathology.

Dataset Distillation (DD) synthesizes a compact synthetic dataset that preserves the training utility of a full dataset. However, its standard formulation assumes that test data follow the same distribution as training data, an assumption that rarely holds in practice. A straightforward extension-applying post-hoc Domain Generalization (DG) techniques to distilled data-is ill-suited because existing DG methods rely on the natural diversity of real datasets, which compact synthetic sets inherently lack, while also incurring substantial augmentation overhead that conflicts with the efficiency objective of dataset distillation. To address this limitation, we introduce Domain Generalizable Dataset Distillation (DGDD), a new problem setting that explicitly targets out-of-distribution (OOD) generalization of distilled datasets. We study this problem through a widely adopted DD baseline of Distribution Matching (DM). We attribute the OOD vulnerability of DM to the entanglement of class-discriminative and domain-specific information within the compressed synthetic set, and propose Spectral Gradient Surgery (SGS) to disentangle the two. The key insight of SGS is that cross-domain agreement among domain-wise gradients in the spectral domain reveals which gradient components are shared across source domains-and are therefore class-discriminative-and which are domain-specific. Based on this observation, SGS augments the standard DM update with two complementary gradients: one that reinforces cross-domain shared components and another that explicitly promotes diversity within the distilled dataset. Extensive experiments on diverse-scale benchmarks demonstrate that SGS substantially improves OOD generalization while remaining plug-and-play compatible with existing DM methods.

Pedestrian motion, due to its causal nature, is strongly influenced by domain gaps arising from discrepancies between training and testing data distributions. Focusing on 3D human pose estimation, this work presents a controllable human pose generation framework that synthesizes diverse video data by systematically varying poses, backgrounds, and camera viewpoints. This generative augmentation enriches training datasets, enhances model generalization, and alleviates the limitations of existing methods in handling domain discrepancies. By leveraging both indoor/real-world and outdoor/virtual datasets, we perform cross-domain data fusion and controllable video generation to construct enriched training data, tailored to realistic deployment settings. Extensive experiments show that the augmented datasets significantly improve model performance on unseen scenarios and datasets, validating the effectiveness of the proposed approach.

Multimodal learning seeks to integrate information across diverse sensory sources, yet current approaches struggle to balance cross-modal generalizability with modality-specific structure. Continuous (implicit) methods preserve fine-grained priors but render generalization challenging, while discrete (explicit) approaches enforce shared prototypes at the expense of modality specificity. We introduce CoDAAR (Cross-modal Discrete Alignment And Reconstruction), a novel framework that resolves this long-standing trade-off by establishing semantic consensus across modality-specific codebooks through index-level alignment. This design uniquely allows CoDAAR to preserve modality-unique structures while achieving generalizable cross-modal representations within a unified discrete space. CoDAAR combines two complementary mechanisms: Discrete Temporal Alignment (DTA), which enables fine-grained temporal quantization, and Cascading Semantic Alignment (CSA), which promotes progressive cross-modal semantic agreement. Together, they establish a competition-free unified representation space. Trained with self-supervised reconstruction objectives on paired multimodal sequences, CoDAAR demonstrates robust cross-modal and cross-domain generalization. Across Cross-Modal Generalization benchmarks, including event classification, localization, video segmentation, and cross-dataset transfer, CoDAAR achieves state-of-the-art performance, establishing a new paradigm for discrete and generalizable multimodal representation learning.

Medical image segmentation is a critical task in computer-aided diagnosis and treatment planning. However, deep learning models often struggle to generalize across datasets due to domain shifts arising from variations in imaging protocols, scanner types, and patient populations. Traditional domain generalization (DG) methods utilize causal feature learning, adversarial consistency, and style augmentation to improve segmentation robustness. While effective, these approaches rely on explicit feature alignment, adversarial objectives, or handcrafted augmentations, which may not fully exploit the capabilities of foundation models. Recently, the Segment Anything Model (SAM) has demonstrated strong generalization capabilities in segmentation tasks. SAM-based DG methods attempt to improve medical image segmentation. However, these approaches primarily operate in the spatial domain and overlook frequency-based discrepancies that significantly affect model robustness. In this work, we propose Frequency-based Domain Generalization with SAM (FSAM), a novel framework that integrates Low-Rank Adaptation (LoRA) for efficient fine-tuning and a frequency adapter to incorporate frequency-domain representations for single-source domain generalization. FSAM enhances SAM's segmentation robustness by extracting domain-invariant high-frequency features, mitigating frequency-related domain shifts. Experimental results on fundus and prostate datasets demonstrate that FSAM outperforms existing traditional DG and SAM-based DG approaches in domain generalization. Codes and pre-trained models will be made available on GitHub.

We introduce BEACON--Best-Effort Adaptation for Cross-Domain Co-Training--a theory-driven framework for training generative robot policies with abundant source demonstrations and limited target demonstrations. BEACON casts cross-domain co-training as a discrepancy-aware importance-reweighting problem, jointly learning a diffusion-based visuomotor policy and per-sample source weights that minimize an objective informed by target-domain generalization guarantees. To make best-effort adaptation practical for high-dimensional sequence policies, we develop scalable instance-level discrepancy estimators, stochastic alternating updates for policy and weights, and a multi-source extension that balances heterogeneous source domains. Across sim-to-sim, sim-to-real, and multi-source manipulation settings, BEACON improves robustness and data efficiency over target-only, fixed-ratio co-training, and feature-alignment baselines. Importantly, even without an explicit alignment objective, BEACON achieves feature alignment as an implicit result of discrepancy-aware cross-domain co-training.

Despite the growing popularity of Multimodal Domain Generalization (MMDG) for enhancing model robustness, it remains unclear whether reported performance gains reflect genuine algorithmic progress or are artifacts of inconsistent evaluation protocols. Current research is fragmented, with studies varying significantly across datasets, modality configurations, and experimental settings. Furthermore, existing benchmarks focus predominantly on action recognition, often neglecting critical real-world challenges such as input corruptions, missing modalities, and model trustworthiness. This lack of standardization obscures a reliable assessment of the field's advancement. To address this issue, we introduce MMDG-Bench, the first unified and comprehensive benchmark for MMDG, which standardizes evaluation across six datasets spanning three diverse tasks: action recognition, mechanical fault diagnosis, and sentiment analysis. MMDG-Bench encompasses six modality combinations, nine representative methods, and multiple evaluation settings. Beyond standard accuracy, it systematically assesses corruption robustness, missing-modality generalization, misclassification detection, and out-of-distribution detection. With 7, 402 neural networks trained in total across 95 unique cross-domain tasks, MMDG-Bench yields five key findings: (1) under fair comparisons, recent specialized MMDG methods offer only marginal improvements over ERM baseline; (2) no single method consistently outperforms others across datasets or modality combinations; (3) a substantial gap to upper-bound performance persists, indicating that MMDG remains far from solved; (4) trimodal fusion does not consistently outperform the strongest bimodal configurations; and (5) all evaluated methods exhibit significant degradation under corruption and missing-modality scenarios, with some methods further compromising model trustworthiness.

Domain generalization requires identifying stable representations that support reliable classification across domains. Domains may differ in low-level attributes, such as color, texture, or visual style, while preserving the same structural relationships among their underlying components. Existing methods primarily address these differences by improving the training process or aligning features across domains. However, since they leave this shared compositional structure implicit, they may overlook a more reliable source of invariance and consequently generalize less effectively to unseen domains. We propose Compositional Relational Invariance from Spatial Primitives (CRISP), an image classification framework that factors visual recognition into visual primitives and their relational composition. We represent these compositions using soft unary, binary, and ternary predicates over primitive locations and appearance, yielding differentiable measures of spatial and visual alignment that can be learned end-to-end. To learn primitives and relational structure jointly, we design an end-to-end architecture with three components: (1) a visual backbone that extracts generalized features, (2) a concept bottleneck layer that maps these features to primitive heatmaps with differentiable spatial coordinates, and (3) a structural scoring layer that evaluates candidate spatial relations among the detected primitives. Finally, we compute class probability from the joint evidence of its class-specific relational compositions and localized primitive appearance. We evaluate \method{} on five real-world image-classification datasets from the widely used DomainBed suite, covering shifts in depiction style, dataset provenance, and camera-trap location and achieving the new state-of-the-art on both benchmarks.

Domain Generalization (DG) aims to learn representations that remain robust under out-of-distribution (OOD) shifts and generalize effectively to unseen target domains. While recent invariant learning strategies and architectural advances have achieved strong performance, explicitly discovering a structured domain-invariant subspace through second-order statistics remains underexplored. In this work, we propose CPCANet, a novel framework grounded in Common Principal Component Analysis (CPCA), which unrolls the iterative Flury-Gautschi (FG) algorithm into fully differentiable neural layers. This approach integrates the statistical properties of CPCA into an end-to-end trainable framework, enforcing the discovery of a shared subspace across diverse domains while preserving interpretability. Experiments on four standard DG benchmarks demonstrate that CPCANet achieves state-of-the-art (SOTA) performance in zero-shot transfer. Moreover, CPCANet is architecture-agnostic and requires no dataset-specific tuning, providing a simple and efficient approach to learning robust representations under distribution shift. Code is available at https://github.com/wish44165/CPCANet.

Mechanical equipment forms the critical backbone of modern industrial production, yet domain shift severely limits the generalization of deep learning based fault diagnosis models across different equipment and operating conditions.Inspired by the success of foundation models in achieving zero-shotgeneralization, we propose YOTOnet (You Only Train Once), a novel architecture specifically designed for cross-domain fault diagnosis in mechanical equipment.YOTOnet comprises three core components: (1) a physics-aware Invariant Feature Distiller that extracts domain-agnostic representations using multi-scale dilated convolutions and FFT-based time-frequency fusion,(2) Domain-Conditioned Sparse Experts (DC-MoE) that adaptively route inputs to specialized processors via learned gating without external meta-data, and (3) a dual-head classification system with auxiliary supervision.Extensive validation on five public bearing datasets (CWRU, MFPT, XJTU,OTTAWA, HUST) through 30 cross-dataset protocols demonstrates the superiority of YOTOnet compared with other state-of-the-art methods. Critically, we observe a clear scaling effect-average test F1 improves from 0.5339(1 training dataset) to 0.705 (4 datasets), with a clear gain when moving from 3 to 4 datasets. These findings provide empirical evidence that foundation model principles can enable robust, train-once deployment for industrial fault diagnosis.

Deploying multimodal models in real-world scenarios requires generalization to new environments where recording conditions differ from training, a challenge known as multimodal domain generalization (MMDG). Standard architectures employ separate encoders for each modality and a fusion module, training the system end-to-end by optimizing on the fused features. In this paper, we identify that such joint optimization causes encoders to exploit cross-modal co-occurrences, statistical relationships between modalities that arise from source-specific recording conditions, rather than learning domain-invariant features. We term this failure mode Fusion Overfitting. To address this, we propose Modality-Entropy Regularization for Domain Generalization (MER-DG), which maximizes the entropy of each encoder's feature distribution to preserve feature diversity. MER-DG is architecture-agnostic and integrates into existing multimodal frameworks as an additive loss term. Extensive experiments on EPIC-Kitchens and HAC benchmarks demonstrate average improvements of approximately 5% over standard fusion and approximately 2% over state-of-the-art methods.

Detectors often suffer from degraded performance, primarily due to the distributional gap between the source and target domains. This issue is especially evident in single-source domains with limited data, as models tend to rely on confounders (e.g., illumination, co-occurrence, and style) from the source domain, leading to spurious correlations that hinder generalization. To this end, this paper proposes a novel Basis-driven framework for domain generalization, namely \textbf{\textit{Bridge}}, that incorporates causal inference into object detection. By learning the low-rank bases for front-door adjustment, \textbf{\textit{Bridge}} blocks confounders' effects to mitigate spurious correlations, while simultaneously refining representations by filtering redundant and task-irrelevant components. \textbf{\textit{Bridge}} can be seamlessly integrated with both discriminative (e.g., DINOv2/3, SAM) and generative (e.g., Stable Diffusion) Vision Foundation Models (VFMs). Extensive experiments across multiple domain generalization object detection datasets, i.e., Cross-Camera, Adverse Weather, Real-to-Artistic, Diverse Weather Datasets, and Diverse Weather DroneVehicle (our newly augmented real-world UAV-based benchmark), underscore the superiority of our proposed method over previous state-of-the-art approaches. The project page is available at: https://mingbohong.github.io/Bridge/.

Federated domain generalization for person re-identification (FedDG-ReID) aims to collaboratively train a pedestrian retrieval model across multiple decentralized source domains such that it can generalize to unseen target environments without compromising raw data privacy. However, this task is significantly challenged by the inherent stylistic gaps across decentralized clients. Without global supervision, models easily succumb to shortcut learning where representations overfit to domain specific camera biases rather than universal identity features. We propose CO-EVO, a novel federated framework that resolves this semantic-style conflict through a co-evolutionary mechanism. On the semantic side, Camera-Invariant Semantic Anchoring (CSA) learns identity prompts with cross-camera consistency to establish purified and domain-agnostic anchors that filter out local imaging noise. On the visual side, Global Style Diversification (GSD), powered by a Global Camera-Style Bank (GCSB), synthesizes realistic perturbations to expand the visual boundaries of training data. The core of CO-EVO is its co-evolutionary loop where purified anchors act as gravitational centers to guide the image encoder toward robust anatomical attributes amidst diverse style variations. Extensive experiments demonstrate that CO-EVO achieves state-of-the-art (SOTA) performance, proving that the synergy between semantic purification and style expansion is essential for robust cross-domain generalization. Our code is available at: https://github.com/NanYiyuzurn/ACL-LGPS-2026.

Exploiting deep learning in medical imaging faces critical challenges, including strict privacy constraints, heterogeneous imaging devices with varying acquisition properties, and class imbalance due to the uneven prevalence of pathologies. In this work, we propose FedSSG, a novel Federated Learning framework that addresses domain shifts caused by diverse imaging devices while mitigating the under-representation of rare pathologies. The key contribution is a strategy for generating synthetic samples and distributing them across clients to improve coverage of both underrepresented pathologies and imaging devices. Experimental results demonstrate that our approach significantly enhances model performance and generalization across heterogeneous institutions, with minimal computational overhead at the client side.

Fault diagnosis under unseen operating conditions remains highly challenging when labeled data are scarce. Semi-supervised domain generalization fault diagnosis (SSDGFD) provides a practical solution by jointly exploiting labeled and unlabeled source domains. However, existing methods still suffer from two coupled limitations. First, pseudo-labels for unlabeled domains are typically generated primarily from knowledge learned on the labeled source domain, which neglects domain-specific geometric discrepancies and thus induces systematic cross-domain pseudo-label bias. Second, unlabeled samples are commonly handled with a hard accept-or-discard strategy, where rigid thresholding causes imbalanced sample utilization across domains, while hard-label assignment for uncertain samples can easily introduce additional noise. To address these issues, we propose a unified framework termed domain-aware hierarchical contrastive learning (DAHCL) for SSDGFD. Specifically, DAHCL introduces a domain-aware learning (DAL) module to explicitly capture source-domain geometric characteristics and calibrate pseudo-label predictions across heterogeneous source domains, thereby mitigating cross-domain bias in pseudo-label generation. In addition, DAHCL develops a hierarchical contrastive learning (HCL) module that combines dynamic confidence stratification with fuzzy contrastive supervision, enabling uncertain samples to contribute to representation learning without relying on unreliable hard labels. In this way, DAHCL jointly improves the quality of supervision and the utilization of unlabeled samples. Furthermore, to better reflect practical industrial scenarios, we incorporate engineering noise into the SSDGFD evaluation protocol. Extensive experiments on three benchmark datasets demonstrate that...

Automatic pancreas segmentation is fundamental to abdominal MRI analysis, yet deep learning models trained on one MRI sequence often fail catastrophically when applied to another-a challenge that has received little systematic investigation. We introduce CrossPan, a multi-institutional benchmark comprising 1,386 3D scans across three routinely acquired sequences (T1-weighted, T2-weighted, and Out-of-Phase) from eight centers. Our experiments reveal three key findings. First, cross-sequence domain shifts are far more severe than cross-center variability: models achieving Dice scores above 0.85 in-domain collapse to near-zero (<0.02) when transferred across sequences. Second, state-of-the-art domain generalization methods provide negligible benefit under these physics-driven contrast inversions, whereas foundation models like MedSAM2 maintain moderate zero-shot performance through contrast-invariant shape priors. Third, semi-supervised learning offers gains only under stable intensity distributions and becomes unstable on sequences with high intra-organ variability. These results establish cross-sequence generalization-not model architecture or center diversity-as the primary barrier to clinically deployable pancreas MRI segmentation. Dataset and code are available at https://crosspan.netlify.app/.

Generalizable gaze estimation methods have garnered increasing attention due to their critical importance in real-world applications and have achieved significant progress. However, they often overlook the effect of label noise, arising from the inherent difficulty of acquiring precise gaze annotations, on model generalization performance. In this paper, we are the first to comprehensively investigate the negative effects of label noise on generalization in gaze estimation. Further, we propose a novel solution, called See-Through-Noise (SeeTN) framework, which improves generalization from a novel perspective of mitigating label noise. Specifically, we propose to construct a semantic embedding space via a prototype-based transformation to preserve a consistent topological structure between gaze features and continuous labels. We then measure feature-label affinity consistency to distinguish noisy from clean samples, and introduce a novel affinity regularization in the semantic manifold to transfer gaze-related information from clean to noisy samples. Our proposed SeeTN promotes semantic structure alignment and enforces domain-invariant gaze relationships, thereby enhancing robustness against label noise. Extensive experiments demonstrate that our SeeTN effectively mitigates the adverse impact of source-domain noise, leading to superior cross-domain generalization without compromising the source-domain accuracy, and highlight the importance of explicitly handling noise in generalized gaze estimation.

We propose a novel swap-adversarial framework that mitigates high inter-subject variability and the high-dimensional low-sample-size problem in electrocorticography (ECoG) data. It achieves robust domain generalization across ECoG and electroencephalography (EEG)-based brain-computer interface datasets. Our framework integrates (1) robust preprocessing, (2) inter-subject balanced channel swap (ISBCS) for cross-subject augmentation, and (3) domain-adversarial learning (DAL) to suppress subject-specific bias. The ISBCS method is a bio-inspired channel swapping strategy that exchanges only functionally corresponding channels across subjects, guided by a brain map, to mitigate inter-subject distribution differences. The DAL strategy encourages the model to learn task-relevant shared features. We validate the effectiveness of this framework through extensive experiments under cross-subject, cross-session, and cross-dataset settings. Our framework consistently outperforms all baselines across all settings, showing the most significant improvements in highly variable environments. It also achieves superior cross-dataset performance between public EEG benchmarks, demonstrating strong generalization capability not only for ECoG but also for EEG data. In addition, we introduce a new ECoG dataset, the first reproducible benchmark, which is constructed from long-term ECoG recordings of 6-hydroxydopamine-induced rat models and annotated with neural responses measured before and after electrical stimulation.

Face Anti-Spoofing (FAS) is essential for the security of facial recognition systems in diverse scenarios such as payment processing and surveillance. Current multimodal FAS methods often struggle with effective generalization, mainly due to modality-specific biases and domain shifts. To address these challenges, we introduce the \textbf{M}ulti\textbf{m}odal \textbf{D}enoising and \textbf{A}lignment (\textbf{MMDA}) framework. By leveraging the zero-shot generalization capability of CLIP, the MMDA framework effectively suppresses noise in multimodal data through denoising and alignment mechanisms, thereby significantly enhancing the generalization performance of cross-modal alignment. The \textbf{M}odality-\textbf{D}omain Joint \textbf{D}ifferential \textbf{A}ttention (\textbf{MD2A}) module in MMDA concurrently mitigates the impacts of domain and modality noise by refining the attention mechanism based on extracted common noise features. Furthermore, the \textbf{R}epresentation \textbf{S}pace \textbf{S}oft (\textbf{RS2}) Alignment strategy utilizes the pre-trained CLIP model to align multi-domain multimodal data into a generalized representation space in a flexible manner, preserving intricate representations and enhancing the model's adaptability to various unseen conditions. We also design a \textbf{U}-shaped \textbf{D}ual \textbf{S}pace \textbf{A}daptation (\textbf{U-DSA}) module to enhance the adaptability of representations while maintaining generalization performance. These improvements not only enhance the framework's generalization capabilities but also boost its ability to represent complex representations. Our experimental results on four benchmark datasets under different evaluation protocols demonstrate that the MMDA framework outperforms existing state-of-the-art methods in terms of cross-domain generalization and multimodal detection accuracy. The code will be released soon.

This paper studies continual test-time adaptation (CTTA), the task of adapting a model to constantly changing unseen domains in testing while preserving previously learned knowledge. Existing CTTA methods mostly focus on adaptation to the current test domain only, overlooking generalization to arbitrary test domains a model may face in the future. To tackle this limitation, we present a novel online test-time domain generalization framework for CTTA, dubbed TestDG. TestDG aims to learn features invariant to both current and previous test domains on the fly during testing, improving the potential for effective generalization to future domains. To this end, we propose a new model architecture and a test-time adaptation strategy dedicated to learning domain-invariant features, along with prototype selection and update mechanisms for effectively managing information from previous test domains. TestDG achieved state of the art on four public CTTA benchmarks. Moreover, it showed superior generalization to unseen test domains.