Learning to Configure Agentic AI Systems

Automated design and optimization of agentic LLM-based systems leads to sophisticated systems that substantially improve result quality over off-the-shelf agentic patterns. However, studies of fielded agentic systems show that production systems focus much more on issues such as simplicity, controllability, and predictability of inference costs. In this paper we propose principled approaches to designing and optimizing practical agentic systems. We describe an agent framework that enables designers to enforce modularity in agentic systems, by defining "pseudo-tools" that call LLMs recursively on a restricted context. Using this framework we hand-engineer agents for a diverse set of tasks, and show that relative to dynamically-planned workflows, hand-constructed fixed workflows are generally cheaper and more accurate. We then propose novel learning methods for the agentic components required by this framework, namely pseudo-tools and fixed workflows. These learning methods generally outperform hand-engineered agents. We also exploit the modularity of the framework to apply multi-objective optimization methods to jointly optimize cost and response quality and blend the results of multiple learning systems.

Large Language Models (LLMs) have revolutionized AI research and enabled exciting agent systems. To build a complex LLM agent system, most existing research relies on insights from other domains or heuristics to manually build the agent system. However, this approach often requires heavy hand-engineering and fails to fully optimize for the downstream task of interest. Inspired by the tremendous success of deep learning, we propose to construct LLM agent systems in a modular manner, similar to building a deep neural network. Our key insight is to make analogies between LLM building blocks, such as retrievals, memories, and prompting strategies, and the successful deep learning modules, such as MLPs, attention, and recurrent modules. We further design forward inference and feedback mechanisms for LLMs, where prompts in LLMs are considered as the weights in deep models, and the prompt optimization from feedback is analogous to the back-propagation algorithm. We additionally leverage a search algorithm to search for the best configuration of LLM agent systems, similar to the neural architecture search (NAS) in deep learning research. Comprehensive experimental results demonstrate that the proposed deep learning recipe for LLM agent systems is highly effective, in particular: (1) Organizing LLM modules into deep-learning-style architectures yields noticeable performance gain; (2) Automatic prompt optimization, equivalent to backpropagation, is efficient in incorporating feedback from the task of interest and achieves at least 5% performance improvement; (3) NAS equivalent algorithm works well for further optimizing the LLM agent system architecture with 11% performance gain compared with randomly designed architectures. Overall, our research demonstrates the exciting opportunity of transferring the success of deep learning to building LLM agent systems.

Agentic AI systems built on large language models (LLMs) offer significant potential for automating complex workflows, from software development to customer support. However, LLM agents often underperform due to suboptimal configurations; poorly tuned prompts, tool descriptions, and parameters that typically require weeks of manual refinement. Existing optimization methods either are too complex for general use or treat components in isolation, missing critical interdependencies. We present ARTEMIS, a no-code evolutionary optimization platform that jointly optimizes agent configurations through semantically-aware genetic operators. Given only a benchmark script and natural language goals, ARTEMIS automatically discovers configurable components, extracts performance signals from execution logs, and evolves configurations without requiring architectural modifications. We evaluate ARTEMIS on four representative agent systems: the ALE Agent for competitive programming on AtCoder Heuristic Contest, achieving a \textbf{$13.6\%$ improvement} in acceptance rate; the Mini-SWE Agent for code optimization on SWE-Perf, with a statistically significant 10.1% performance gain; and the CrewAI Agent for cost and mathematical reasoning on Math Odyssey, achieving a statistically significant \textbf{$36.9\%$ reduction} in the number of tokens required for evaluation. We also evaluate the MathTales-Teacher Agent powered by a smaller open-source model (Qwen2.5-7B) on GSM8K primary-level mathematics problems, achieving a 22% accuracy improvement and demonstrating that ARTEMIS can optimize agents based on both commercial and local models.