Toward a Fully Autonomous, AI-Native Particle Accelerator

We present the first language-model-driven agentic artificial intelligence (AI) system to autonomously execute multi-stage physics experiments on a production synchrotron light source. Implemented at the Advanced Light Source particle accelerator, the system translates natural language user prompts into structured execution plans that combine archive data retrieval, control-system channel resolution, automated script generation, controlled machine interaction, and analysis. In a representative machine physics task, we show that preparation time was reduced by two orders of magnitude relative to manual scripting even for a system expert, while operator-standard safety constraints were strictly upheld. Core architectural features, plan-first orchestration, bounded tool access, and dynamic capability selection, enable transparent, auditable execution with fully reproducible artifacts. These results establish a blueprint for the safe integration of agentic AI into accelerator experiments and demanding machine physics studies, as well as routine operations, with direct portability across accelerators worldwide and, more broadly, to other large-scale scientific infrastructures.

Accelerating applications through the design of hardware accelerators can significantly enhance system performance and energy efficiency. Despite advances, such as high-level synthesis (HLS), designing accelerators for complex applications still remains highly labor-intensive, demanding considerable expertise in understanding workloads to be accelerated, hardware design, micro-architecture, and EDA tool usage, posing challenges for application domain experts. Therefore, most accelerator solutions are limited to applications with a regular predictable dataflow. Advances in AI have enabled agents that perform autonomous planning, reasoning, execution and reflection, leading to unprecedented potential for automation through agentic AI. We present A3D, an Agentic AI flow for end-to-end Automation of hardware Accelerator Design. A3D automates workload analysis, performance bottleneck identification, code refactoring for HLS compatibility and micro-architecture generation. A3D also generates diverse accelerator designs by automatically exploring the speed-area tradeoff space. Recent efforts have explored the use of AI for specific tasks such as design space exploration in HLS, leaving several tasks to still be performed manually. A3D addresses the challenges in applying modern LLMs to accelerator design by judiciously partitioning tasks among specialist agents, orchestrating process loops with specialist and verifier agents, utilizing pre-existing and custom tools, and employing agentic RAG for codebase and proprietary EDA tool documentation exploration. Our implementation of A3D, using commercial components like Claude Sonnet 4.5 and the Catapult HLS tool, demonstrates its effectiveness by generating accelerator designs with no human intervention from complex scientific applications like LAMMPS (molecular dynamics simulation) and QMCPACK (quantum chemistry).

As large models evolve from conversational assistants into autonomous agents, challenges increasingly arise from long-horizon decision making, tool use, and real environment interaction. Existing agenticinfrastructure remain fragmented across evaluation, data management, and agent evolution, making it difficult to discover risks systematically and improve models in a continuous closed loop. In this report, we present Safactory, a scalable agent factory for trustworthy autonomous intelligence. Safactory integrates three tightly coupled platforms: a Parallel Simulation Platform for trajectory generation, a Trustworthy Data Platform for trajectory storage and experience extraction, and an Autonomous Evolution Platform for asynchronous reinforcement learning and on-policy distillation. As far as we know, Safactory is the first framework to propose a unified evolutionary pipeline for next-generation trustworthy autonomous intelligence.