Towards Real-World Identification of Fatigued Muscle Groups via Musculoskeletal Simulation

Detecting muscle fatigue via surface electromyography (sEMG) is essential for applications in sports, rehabilitation, and wearable health monitoring. Accurate and timely detection of fatigue is crucial for preventing injuries, optimizing physical performance, and ensuring user safety during prolonged activity. However, existing deep learning models are often unsuitable for this task due to their high computational cost and dependence on large-scale data. In this work, we propose an energy-efficient framework for muscle fatigue detection based on Spiking Neural Networks (SNNs), which exploit sparse, event-driven computation and temporal modeling. We further introduce a quantization-compatible training scheme (SDH) that combines multiple regularization terms to improve robustness under noisy conditions. Evaluated on two public sEMG datasets against a broad set of baselines and under seven noise conditions including physically motivated perturbations, our quantized SNNs match or exceed strong baselines while remaining more stable under diverse noise and reducing estimated energy consumption by up to 201.77x. These results demonstrate the framework's strong potential for real-time deployment in low-power wearable systems.

Quantitative assessment of muscle MRI is crucial for monitoring neuromuscular disorders (NMD). This study introduces an automated radiomic phenotyping framework based on original features engineered across five main architectural domains: quantitative morphometry, spatial distribution, geometric shape, interactions between progressive fat replacement stages, and graph-based topology. Utilizing 1184 MRI scans from the CoMPaSS-NMD project, we map the complex 3D architecture of heterogeneous intramuscular lipodegeneration into objective, morphologically interpretable biomarkers. We introduce a graph-based skeletonization of fat infiltrates to quantify muscle architectural changes, establishing a multi-dimensional extension of traditional, spatially-agnostic volume metrics by mapping topological networks across the entire 3D muscle volume. Statistical screening via non-parametric Kruskal-Wallis analysis confirmed the discriminative power of these novel descriptors across the genetic hierarchy. Notably, topological network metrics (e.g., SF1_Skel_Nodes, $\epsilon^2$ = 0.2656) and interface dynamics metrics (e.g., SF2_To_SF1_Dist_Min, $\epsilon^2$ = 0.2092) demonstrated substantial effect sizes, providing deeper structural insights than classical volumetric assessments. Post-hoc pairwise evaluations and UMAP projections further indicated the capability of these topological and 3D geometric invariants to capture disease-specific macroscopic infiltration patterns. These results demonstrate that global architectural features represent a highly promising class of biomarkers for differential diagnosis, offering new avenues for tracking longitudinal disease dynamics in neuromuscular diagnostics. The developed automated feature extraction pipeline is integrated and available within the MUSCAT (MUSCle fAt Topology) library.

Training machine learning models for robotic tactile sensing requires vast amounts of data, yet obtaining realistic interaction data remains a challenge due to physical complexity and variability. Simulating tactile sensors is thus a crucial step in accelerating progress. This paper presents SPLIT, a novel method for simulating image-based tactile sensors, with a primary focus on the DIGIT sensor. Central to our approach is a latent space arithmetic strategy that explicitly disentangles contact geometry from sensor-specific optical properties. Unlike methods that require recalibration for every new unit, this disentanglement allows SPLIT to adapt to diverse DIGIT backgrounds and even transfer data to distinct sensors like the GelSight R1.5 without full model retraining. Beyond this adaptability, our approach achieves faster inference speeds than existing alternatives. Furthermore, we provide a calibrated finite element method (FEM) soft-body mesh simulation with variable resolution, offering a tunable trade-off between speed and fidelity. Additionally, our algorithm supports bidirectional simulation, allowing for both the generation of realistic images from deformation meshes and the reconstruction of meshes from tactile images. This versatility makes SPLIT a valuable tool for accelerating progress in robotic tactile sensing research.