cs.CVJul 22, 2026

CrossSpine: Multi-scale Cross-sequence Attention with Anatomical Priors for Automated Pfirrmann Grading

Authors: Hai Son NguyenDuong Ngoc VuTrong-Nghia NguyenBien Tran VanVan-Dem PhamTrang Mai XuanHuan VuThien Van Luong

Organizations: Business AI Lab, College of Technology, National Economics University, Vietnam · Medical Imaging & Radiological Technology Department, Faculty of Medical Technology, Phenikaa School of Medicine & Pharmacy, Phenikaa University, Vietnam · Radiology & Functional Exploration Center, Phenikaa University Hospital, Vietnam · Deparment of Pediatrics, Hospital of University Medicine and Pharmacy, Vietnam National University, Hanoi, Vietnam · A2I Lab, Phenikaa School of Computing, Phenikaa University, Hanoi, Vietnam

Abstract

Automated grading of Lumbar Disc Degeneration is essential for the objective quantification of structural changes associated with low back pain. Observing that baseline models underperformed on our data, we propose a framework designed to overcome these limitations. First, we present the Cross-sequence Attention Spine (CrossSpine) framework, a novel architecture that employs a cross-sequence attention mechanism to adaptively fuse features from different MRI sequences at multiple spa- tial scales. Second, we contribute a meticulously curated dataset aimed at automated Pfirrmann grading. Finally, we introduce an IVD-aware classification technique that integrates anatomical disc-level information, enabling the model to learn level-specific degeneration priors. Our experi- ments demonstrate the superiority of this approach: CrossSpine achieved a relative improvement exceeding 125% in the Macro F1 score, while boosting the Mean AUPRC by 99% and the Mean AUROC by 36% com- pared to the baseline.

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