"Why is my period late?" Sometimes, the most useful response begins with another question. Yet conversational AI systems may respond to incomplete health queries without seeking essential context or grounding their guidance in verifiable evidence. This paper introduces HerHealthGPT, an evidence-grounded conversational AI system designed to address these challenges in women's reproductive health. HerHealthGPT integrates retrieval-augmented generation (RAG), context-aware clarification, and source validation within an interactive web interface. Rather than responding immediately to incomplete queries, the system maintains conversational context, asks targeted follow-up questions, checks for premature conclusions, and grounds its responses in retrieved evidence. We evaluate the AI components using 540 English messages derived from 90 reproductive-health cases and conduct a prototype questionnaire study with 30 adults. Evidence retrieval improves concern-category accuracy from 54.1% to 59.3% compared with fine-tuning alone. The clarification router achieves 85.6% recall and 86.2% specificity on constructed targets. In the user study, 83.3% of participants preferred the retrieval-enabled configuration, while 25 of 30 considered its follow-up questions relevant. These findings suggest that integrating evidence retrieval with interactive clarification offers a promising approach to more transparent, context-aware reproductive-health information systems, while further clinical validation remains necessary.
Figures & tables
Fig. 1 : Four-layer architecture of HerHealthGPT, integrating the consumer interface, application services, model inference and retrieval, and persistent storage.
Fig. 2 : HerHealthGPT conversational workflow. Each turn combines conversation history and retrieved evidence to generate a structured decision. A premature-conclusion check may trigger one revision before validation, storage, and response delivery.
Fig. 3 : Prototype screens. 1 1 1 The interactive prototype of the proposed system is available at: https://herhealthgpt.org/ . (a) Onboarding on a phone-sized screen; (b) one follow-up question per turn, each with its sources; (c) a routine-appointment conclusion with the quoted source sentences and disclaimer; (d) an inform answer to a general question, with citations and no urgency level. The examples show interface behavior, not clinical endorsements.
System
Configuration
A
Base Qwen3.5-9B with instructions
B
QLoRA-adapted Qwen3.5-9B
C
QLoRA-adapted Qwen3.5-9B + RAG
TABLE I : Configurations in the consumer study.
Configuration
Category
Compatible
Risk
Under-triage ↓
Clar. recall
Clar. spec.
ZS
53.9
62.2
66.7
71.8
85.6
86.2
Base+RAG
56.1
64.7
65.0
73.6
66.7
94.7
FT
54.1
62.4
68.5
52.9
0.0
100.0
FT+Instruction
54.3
62.6
67.0
58.6
0.0
100.0
FT+Shuffled
53.1
61.3
67.6
59.2
0.0
100.0
FT+Real RAG
59.3
68.4
68.1
56.9
0.0
100.0
TABLE II : English component results. Category accuracy: 540 messages (full) and 468 (compatible); risk: 540; under-triage: 174; clarification recall: 90 and specificity: 450. All values are percentages.
Patient portals now give individuals direct access to their electronic health records (EHRs), yet access alone does not ensure patients understand or act on the complex clinical information contained in these records. The ArchEHR-QA 2026 shared task addresses this challenge by focusing on grounded question answering over EHRs, and this paper presents the system developed by the HealthNLP_Retrievers team for this task. The proposed approach uses a multi-stage cascaded pipeline powered by the Gemini 2.5 Pro large language model to interpret patient-authored questions and retrieve relevant evidence from lengthy clinical notes. Our architecture comprises four integrated modules: (1) a few-shot query reformulation unit which summarizes verbose patient queries; (2) a heuristic-based evidence scorer which ranks clinical sentences to prioritize recall; (3) a grounded response generator which synthesizes professional-caliber answers restricted strictly to identified evidence; and (4) a high-precision many-to-many alignment framework which links generated answers to supporting clinical sentences. This cascaded approach achieved competitive results. Across the individual tracks, the system ranked 1st in question interpretation, 5th in answer generation, 7th in evidence identification, and 9th in answer-evidence alignment. These results show that integrating large language models within a structured multi-stage pipeline improves grounding, precision, and the professional quality of patient-oriented health communication. To support reproducibility, our source code is publicly available in our GitHub repository
Medical question-answering benchmarks predominantly evaluate single-turn exchanges, failing to capture the iterative, clarification-seeking nature of real patient consultations. We introduce ThReadMed-QA, a benchmark of 2,437 fully-answered patient-physician conversation threads extracted from r/AskDocs, comprising 8,204 question-answer pairs across up to 9 turns. Unlike prior work relying on simulated dialogues, adversarial prompts, or exam-style questions, ThReadMed-QA captures authentic patient follow-up questions and verified physician responses, reflecting how patients naturally seek medical information online. We evaluate five state-of-the-art LLMs -- GPT-5, GPT-4o, Claude Haiku, Gemini 2.5 Flash, and Llama 3.3 70B -- on a stratified test split of 238 conversations (948 QA pairs) using a calibrated LLM-as-a-judge rubric grounded in physician ground truth. Even the strongest model, GPT-5, achieves only 41.2% fully-correct responses. All five models degrade significantly from turn 0 to turn 2 (p < 0.001), with wrong-answer rates roughly tripling by the third turn. We identify a fundamental tension between single-turn capability and multi-turn reliability: models with the strongest initial performance (GPT-5: 75.2; Claude Haiku: 72.3 out of 100) exhibit the steepest declines by turn 2 (dropping 16.2 and 25.0 points respectively), while weaker models plateau or marginally improve. We introduce two metrics to quantify multi-turn failure modes: Conversational Consistency Score (CCS) and Error Propagation Rate (EPR). CCS reveals that nearly one in three Claude Haiku conversations swings between a fully correct and a completely wrong response within the same thread. EPR shows that a single wrong turn raises the probability of a subsequent wrong turn by 1.9-6.1x across all models.
Monica Munnangi, Saiph Savage
Khoury College of Computer Sciences Northeastern University Boston
Medical question-answering benchmarks rarely cover the maternal, neonatal, child, and reproductive-health questions a nurse-midwife asks, and, to our knowledge, no public chunk-level relevance benchmark exists for maternal-health guideline retrieval. We release two benchmarks that fill these gaps. mamabench is a scope-filtered QA set of 25,949 items assembled from seven existing expert-authored sources across multiple-choice, short-answer, and rubric-graded tracks; to help users calibrate the LLM judge that scores the rubric track, we re-scope HealthBench's physician-labelled meta-evaluation to the domain. mamaretrieval pairs 3,185 clinical queries with graded (0-6) relevance labels over a 63,650-chunk maternal-health guideline corpus, using a decomposed rubric that distinguishes a chunk that answers a query from one merely on its topic. Three decisions shape both: assemble and filter expert sources rather than author questions, grade relevance rather than binarise it, and measure and disclose the limits of the labels -- scope-classifier agreement, a frontier-judge check, and a pooling-completeness audit -- rather than treat them as an oracle. A companion paper uses the benchmarks to evaluate a deployed on-device assistant; both are released openly for research.
Yi Ren
École Polytechnique Fédérale de Lausanne, Switzerland