Self-Supervised Learning

Also known as SSL

Overview

Self-supervised learning creates training signals from the data itself, for example by matching augmented views, predicting masked content, or using temporal, geometric, and physical consistency. Contrastive learning, masked autoencoders, teacher–student distillation, and joint-embedding predictive architectures are common approaches across images, video, audio, language, medical data, and scientific measurements. These methods can reduce dependence on costly labels and support transfer, but useful representations depend on how well the pretext signal fits the data and downstream task. A central tension is balancing invariance and non-collapse with retaining fine-grained information, while establishing reliable transfer under domain shifts and limited compute remains an open challenge.

Latest papers

261 papers32 papers in the last four weeks, up 33% on the four weeks before. 0.2% of all new papers.

Feb 27, 2026

SelfOccFlow: Towards end-to-end self-supervised 3D Occupancy Flow prediction

Estimating 3D occupancy and motion at the vehicle's surroundings is essential for autonomous driving, enabling situational awareness in dynamic environments. Existing approaches jointly learn geometry and motion but rely on expensive 3D occupancy and flow annotations, velocity labels from bounding boxes, or pretrained optical flow models. We propose a self-supervised method for 3D occupancy flow estimation that eliminates the need for human-produced annotations or external flow supervision. Our method disentangles the scene into separate static and dynamic signed distance fields and learns motion implicitly through temporal aggregation. Additionally, we introduce a strong self-supervised flow cue derived from features' cosine similarities. We demonstrate the efficacy of our 3D occupancy flow method on SemanticKITTI, KITTI-MOT, and nuScenes.
Feb 27, 2026

Learning Accurate Segmentation Purely from Self-Supervision

Accurately segmenting objects without any manual annotations remains one of the core challenges in computer vision. In this work, we introduce Selfment, a fully self-supervised framework that segments foreground objects directly from raw images without human labels, pretrained segmentation models, or any post-processing. Selfment first constructs patch-level affinity graphs from self-supervised features and applies NCut to obtain an initial coarse foreground--background separation. We then introduce Iterative Patch Optimization (IPO), a feature-space refinement procedure that progressively enforces spatial coherence and semantic consistency through iterative patch clustering. The refined masks are subsequently used as supervisory signals to train a lightweight segmentation head with contrastive and region-consistency objectives, allowing the model to learn stable and transferable object representations. Despite its simplicity and complete absence of manual supervision, Selfment sets new state-of-the-art (SoTA) results across multiple benchmarks. It achieves substantial improvements on Fmax⁡F_{\max} over previous unsupervised saliency detection methods on ECSSD (+4.0%+4.0\%), HKUIS (+4.6%+4.6\%), and PASCAL-S (+5.7%+5.7\%). Moreover, without any additional fine-tuning, Selfment demonstrates remarkable zero-shot generalization to camouflaged object detection tasks (e.g., 0.9100.910 SmS_m on CHAMELEON and 0.7920.792 FβωF_β^ω on CAMO), outperforming all existing unsupervised approaches and even rivaling the SoTA fully supervised methods.
Feb 26, 2026

Brain-OF: An Omnifunctional Foundation Model for fMRI, EEG and MEG

Brain foundation models have achieved remarkable advances across a wide range of neuroscience tasks. However, most existing models are limited to a single functional modality, restricting their ability to exploit complementary spatiotemporal dynamics and the collective data scale across different neuroimaging techniques. This limitation largely arises from severe semantic heterogeneity and resolution discrepancies among modalities. To address these challenges, we propose Brain-OF, an omnifunctional brain foundation model jointly pretrained on fMRI, EEG and MEG, capable of handling both unimodal and multimodal inputs within a unified framework. To reconcile heterogeneous spatiotemporal resolutions, we introduce the Any-Resolution Neural Signal Sampler, which projects diverse brain signals into a shared semantic space. To further manage semantic shifts, the Brain-OF backbone integrates DINT attention with a Sparse Mixture of Experts, where shared experts capture modality-invariant representations and routed experts specialize in modality-specific semantics. Furthermore, to explicitly internalize the characteristics of neural activity through self-supervised learning, we propose Masked Temporal-Frequency Modeling, a dual-domain pretraining objective that jointly reconstructs brain signals in both the time and frequency domains. Brain-OF is pretrained on a large-scale corpus comprising around 40 datasets and demonstrates superior performance across diverse downstream tasks, highlighting the benefits of joint multimodal integration and dual-domain pretraining.
Feb 25, 2026

Learning to reconstruct from saturated data: audio declipping and high-dynamic range imaging

Learning based methods are now ubiquitous for solving inverse problems, but their deployment in real-world applications is often hindered by the lack of ground truth references for training. Recent self-supervised learning strategies offer a promising alternative, avoiding the need for ground truth. However, most existing methods are limited to linear inverse problems. This work extends self-supervised learning to the non-linear problem of recovering audio and images from clipped measurements, by assuming that the signal distribution is approximately invariant to changes in amplitude. We provide sufficient conditions for learning to reconstruct from saturated signals alone and a self-supervised loss that can be used to train reconstruction networks. Experiments on both audio and image data show that the proposed approach is almost as effective as fully supervised approaches, despite relying solely on clipped measurements for training.
Feb 24, 2026

A unified self-supervised framework for single-frame Fresnel CDI and overlapped ptychography

Ptychographic imaging at synchrotron and X-ray free-electron laser sources requires densely overlapping scans, which limits throughput and increases dose; extending coherent diffractive imaging to overlap-free operation on extended samples remains an open problem. We present a self-supervised inverse-mapping network for single-frame Fresnel coherent diffraction imaging (CDI) and overlapped ptychography with fixed, pre-estimated probes. The learned neural network reconstructs individual object patches from either one diffraction frame or several overlapping measurements at a time. In single-frame mode, the phase diversity provided by the curved-wavefront probe at the off-focus sample position removes the requirement for overlap constraints, enabling sparser scans and proportionally lower dose at fixed exposure. On synthetic line patterns, reconstructed amplitude SSIM exceeds 0.90 in single-frame mode with the curved probe and reaches 0.952-0.968 with overlap constraints. Optimization of the network via a Poisson negative log likelihood objective, rather than the more common mean absolute error, yields 10-fold improved photon-dose efficiency at doses below 10510^5 photons per image, where shot noise typically limits resolution. In addition to these synthetic studies, we demonstrate robust single-frame reconstruction of extended samples using ptychographic datasets from APS and LCLS, with end-to-end reconstruction of a 10,304-frame workload approximately 36×36\times faster than a highly optimized iterative solver. Together, these results unify single-frame Fresnel CDI and overlapped ptychography within one self-supervised framework, supporting dose-efficient, high-throughput imaging at modern light sources.
Feb 24, 2026

Spa3R: Predictive Spatial Field Modeling for 3D Visual Reasoning

Vision-language models excel at 2D visual understanding but remain limited in 3D spatial reasoning. Existing approaches either depend on explicit 3D modalities, which limits scalability, or inject partial, view-conditioned geometric priors and leave the language model to recover global scene structure from sparse cues. We introduce Spa3R, a self-supervised framework that learns a unified, view-invariant spatial representation from unposed multi-view RGB images. Its Predictive Spatial Field Modeling objective compresses context views into a compact latent representation and predicts aligned geometric and semantic feature fields at novel viewpoints, thereby encouraging coherent encoding of scene geometry and layout. We integrate the pre-trained Spa3R Encoder into a vision-language model through a lightweight residual cross-attention adapter, yielding Spa3-VLM and grounding language reasoning in global spatial context. Spa3-VLM achieves an average score of 58.6% on VSI-Bench and delivers leading or competitive performance across three additional spatial reasoning benchmarks. These results demonstrate that predictive spatial representation learning provides an effective visual foundation for 3D reasoning.
Feb 23, 2026

Transcending the Annotation Bottleneck: AI-Powered Discovery in Biology and Medicine

The dependence on expert annotation has long constituted the primary rate-limiting step in the application of artificial intelligence to biomedicine. While supervised learning drove the initial wave of clinical algorithms, a paradigm shift towards unsupervised and self-supervised learning (SSL) is currently unlocking the latent potential of biobank-scale datasets. By learning directly from the intrinsic structure of data - whether pixels in a magnetic resonance image (MRI), voxels in a volumetric scan, or tokens in a genomic sequence - these methods facilitate the discovery of novel phenotypes, the linkage of morphology to genetics, and the detection of anomalies without human bias. This article synthesises seminal and recent advances in "learning without labels," highlighting how unsupervised frameworks can derive heritable cardiac traits, predict spatial gene expression in histology, and detect pathologies with performance that rivals or exceeds supervised counterparts.
Feb 22, 2026

TeFlow: Enabling Multi-frame Supervision for Self-Supervised Feed-forward Scene Flow Estimation

Self-supervised feed-forward methods for scene flow estimation offer real-time efficiency, but their supervision from two-frame point correspondences is unreliable and often breaks down under occlusions. Multi-frame supervision has the potential to provide more stable guidance by incorporating motion cues from past frames, yet naive extensions of two-frame objectives are ineffective because point correspondences vary abruptly across frames, producing inconsistent signals. In the paper, we present TeFlow, enabling multi-frame supervision for feed-forward models by mining temporally consistent supervision. TeFlow introduces a temporal ensembling strategy that forms reliable supervisory signals by aggregating the most temporally consistent motion cues from a candidate pool built across multiple frames. Extensive evaluations demonstrate that TeFlow establishes a new state-of-the-art for self-supervised feed-forward methods, achieving performance gains of up to 33% on the challenging Argoverse 2 and nuScenes datasets. Our method performs on par with leading optimization-based methods, yet speeds up 150 times. The code is open-sourced at https://github.com/Kin-Zhang/TeFlow along with trained model weights.
Feb 21, 2026

Robust Self-Supervised Cross-Modal Super-Resolution against Real-World Misaligned Observations

Cross-modal super-resolution (SR) on real-world misaligned data is challenging, as only unlabeled low-resolution (LR) source and high-resolution (HR) guide images with complex spatial misalignment are available. Previous methods either rely on simulated training data or adopt suboptimal alignment strategies that overlook cross-modal dependencies, limiting their practical performance. To address these issues, we propose RobSelf, a self-supervised model that jointly optimizes a misalignment-aware feature translator and a content-aware reference filter online. The translator resolves unsupervised cross-modal and cross-resolution alignment via weakly-supervised, misalignment-aware translation, yielding an aligned guide feature. Guided by this feature, the filter performs reference-based discriminative self-enhancement on the source, enabling SR prediction with high resolution and high fidelity. Experiments on synthesized data and collected real-world data demonstrate that RobSelf achieves state-of-the-art performance, outperforming existing self-supervised and supervised methods. Moreover, it achieves superior efficiency, being up to 15.3×\times faster than prior self-supervised methods.
Feb 17, 2026

What Do Neurons Listen To? A Neuron-level Dissection of a General-purpose Audio Model

In this paper, we analyze the internal representations of a general-purpose audio self-supervised learning (SSL) model from a neuron-level perspective. Despite their strong empirical performance as feature extractors, the internal mechanisms underlying the robust generalization of SSL audio models remain unclear. Drawing on the framework of mechanistic interpretability, we identify and examine class-specific neurons by analyzing conditional activation patterns across diverse tasks. Our analysis reveals that SSL models foster the emergence of class-specific neurons that provide extensive coverage across novel task classes. These neurons exhibit shared responses across different semantic categories and acoustic similarities, such as speech attributes and musical pitch. We also confirm that these neurons have a functional impact on classification performance. To our knowledge, this is the first systematic neuron-level analysis of a general-purpose audio SSL model, providing new insights into its internal representation.
Feb 2, 2026

Self-Supervised Learning from Structural Invariance

Joint-embedding self-supervised learning (SSL), the key paradigm for unsupervised representation learning from visual data, learns from invariances between semantically-related data pairs. We study the one-to-many mapping problem in SSL, where each datum may be mapped to multiple valid targets. This arises when data pairs come from naturally occurring generative processes, e.g., successive video frames. We show that existing methods struggle to flexibly capture this conditional uncertainty. As a remedy, we introduce a latent variable to account for this uncertainty and derive a variational lower bound on the mutual information between paired embeddings. Our derivation yields a simple regularization term for standard SSL objectives. The resulting method, which we call AdaSSL, applies to both contrastive and distillation-based SSL objectives, and we empirically show its versatility in causal representation learning, fine-grained image understanding, and world modeling on videos.
Nov 21, 2025

PrismSSL: One Interface, Many Modalities; A Single-Interface Library for Multimodal Self-Supervised Learning

We present PrismSSL, a Python library that unifies state-of-the-art self-supervised learning (SSL) methods across audio, vision, graphs, and cross-modal settings in a single, modular codebase. The goal of the demo is to show how researchers and practitioners can: (i) install, configure, and run pretext training with a few lines of code; (ii) reproduce compact benchmarks; and (iii) extend the framework with new modalities or methods through clean trainer and dataset abstractions. PrismSSL is packaged on PyPI, released under the MIT license, integrates tightly with HuggingFace Transformers, and provides quality-of-life features such as distributed training in PyTorch, Optuna-based hyperparameter search, LoRA fine-tuning for Transformer backbones, animated embedding visualizations for sanity checks, Weights & Biases logging, and colorful, structured terminal logs for improved usability and clarity. In addition, PrismSSL offers a graphical dashboard - built with Flask and standard web technologies - that enables users to configure and launch training pipelines with minimal coding. The artifact (code and data recipes) will be publicly available and reproducible.
Nov 10, 2025

DIAL-GS: Dynamic Instance Aware Reconstruction for Label-free Street Scenes with 4D Gaussian Splatting

Urban scene reconstruction is critical for autonomous driving, enabling structured 3D representations for data synthesis and closed-loop testing. Supervised approaches rely on costly human annotations and lack scalability, while current self-supervised methods often confuse static and dynamic elements and fail to distinguish individual dynamic objects, limiting fine-grained editing. We propose DIAL-GS, a novel dynamic instance-aware reconstruction method for label-free street scenes with 4D Gaussian Splatting. We first accurately identify dynamic instances by exploiting appearance-position inconsistency between warped rendering and actual observation. Guided by instance-level dynamic perception, we employ instance-aware 4D Gaussians as the unified volumetric representation, realizing dynamic-adaptive and instance-aware reconstruction. Furthermore, we introduce a reciprocal mechanism through which identity and dynamics reinforce each other, enhancing both integrity and consistency. Experiments on urban driving scenarios show that DIAL-GS surpasses existing self-supervised baselines in reconstruction quality and instance-level editing, offering a concise yet powerful solution for urban scene modeling.
Nov 9, 2025

Label-Efficient 3D Forest Mapping: Self-Supervised and Transfer Learning for Instance Segmentation, Semantic Segmentation, and Species Classification

Detailed structural and species information on individual tree level is increasingly important to support precision forestry, biodiversity conservation, and provide reference data for biomass and carbon mapping. Point clouds from airborne and ground-based laser scanning are currently the most suitable data source to rapidly derive such information at scale. Recent advancements in deep learning improved segmenting and classifying individual trees and identifying semantic tree components. However, deep learning models typically require large amounts of annotated training data which limits further improvement. Producing dense, high-quality annotations for 3D point clouds, especially in complex forests, is labor-intensive and challenging to scale. We explore strategies to reduce dependence on large annotated datasets using self-supervised and transfer learning. Our objective is to improve performance across three tasks: instance segmentation, semantic segmentation, and tree classification using realistic and operational training sets. We observe improvements across all tasks, compared to training from scratch, evaluated with their respective metrics. For instance segmentation, self-supervised learning combined with domain adaptation improves AP50 by 16.98%. For semantic segmentation, self-supervised learning alone improves mIoU by 1.79%. For tree classification, hierarchical transfer learning improves mean Jaccard by 6.07%. To simplify use and encourage uptake, we integrated the tasks into a unified framework, streamlining the process from raw point clouds to tree delineation, structural analysis, and species classification. Pretrained models reduce energy consumption and carbon emissions by ~21%. This open-source contribution aims to accelerate operational extraction of individual tree information from laser scanning point clouds to support forestry, biodiversity, and carbon mapping.
Nov 3, 2025

Patent Representation Learning via Self-supervision

We study self-supervised patent representation learning with contrastive objectives. A standard baseline constructs positives by encoding the same text twice under independent dropout masks, but applying this recipe to long, structured patent documents requires careful calibration. We show that dropout-only training can be substantially strengthened by tuning temperature and dropout rate, yet its best configuration is evaluation-dependent and does not transfer uniformly from title--abstract retrieval to claim-to-disclosure retrieval. We propose mixed dropout--section positives, a patent-specific view construction strategy in which each positive pair links the title--abstract view of a patent either to a dropout re-encoding of itself or to another section of the same patent, such as claims, summary, background, drawings, or description. This uses patent-internal structure as a training-time signal without IPC labels, citations, or relevance annotations. We evaluate on graded EPO search-report retrieval, DAPFAM, a recently proposed family-level patent retrieval benchmark, and IPC subclass classification. Section-based positives improve over calibrated dropout-only and generic title--abstract augmentation baselines, are competitive with citation-informed patent encoders and a general-purpose embedding model, and perform strongly on the out-of-domain split of DAPFAM. Additional cross-section alignment diagnostics show that section-pair training improves compatibility among abstracts, claims, and descriptions of the same invention. These results indicate that patent sections provide effective self-supervised positive views for learning dense patent representations.
May 18, 2025

AdaDim: Dimensionality Adaptation for SSL Representational Dynamics

A key factor in effective Self-Supervised learning (SSL) is preventing dimensional collapse, where higher-dimensional representation spaces (RR) span a lower-dimensional subspace. Therefore, SSL optimization strategies involve guiding a model to produce RR with a higher dimensionality (H(R)H(R)) through objectives that encourage decorrelation of features or sample uniformity in RR. A higher H(R)H(R) indicates that RR has greater feature diversity which is useful for generalization to downstream tasks. Alongside dimensionality optimization, SSL algorithms also utilize a projection head that maps RR into an embedding space ZZ. Recent work has characterized the projection head as a filter of noisy or irrelevant features from the SSL objective by reducing the mutual information I(R;Z)I(R;Z). Therefore, the current literature's view is that a good SSL representation space should have a high H(R)H(R) and a low I(R;Z)I(R;Z). However, this view of SSL is lacking in terms of an understanding of the underlying training dynamics that influences the relationship between both terms. Our analysis shows that the best performing SSL models do not have the highest H(R)H(R) nor the lowest I(R;Z)I(R;Z), but effectively arrive at a balance between both. To take advantage of this analysis, we introduce AdaDim, a training strategy that leverages SSL training dynamics by adaptively balancing between increasing H(R)H(R) through feature decorrelation and sample uniformity as well as gradual regularization of I(R;Z)I(R;Z) as training progresses. We show performance improvements of up to 3% over common SSL baselines despite our method not utilizing expensive techniques such as queues, clustering, predictor networks, or student-teacher architectures.
Mar 22, 2025

Meta-Representational Predictive Coding: Neuroscience-Informed Self-Supervised Learning

Self-supervised learning has become an increasingly important paradigm in the domain of machine intelligence. Furthermore, evidence for self-supervised adaptation, such as contrastive formulations, has emerged in recent computational neuroscience and brain-inspired research. Nevertheless, current work on self-supervised learning relies on biologically implausible credit assignment -- in the form of backpropagation of errors -- and feedforward inference, typically a forward-locked pass. Predictive coding, in its mechanistic form, offers a biologically plausible means to sidestep these backprop-specific limitations. However, unsupervised predictive coding rests on learning a generative model of raw input (akin to "generative AI" approaches), which entails predicting a potentially high dimensional input; on the other hand, supervised predictive coding, which learns a mapping between inputs to target labels, requires human annotation, and thus incurs the drawbacks of supervised learning. In this work, we present a scheme for self-supervised learning, specifically for an emerging research sub-domain that we label as neuroscience-informed self-supervised learning (NeuroSSL), within a neurobiologically plausible framework that appeals to the free energy principle, constructing a new form of predictive coding that we call meta-representational predictive coding (MPC). MPC sidesteps the need for learning a generative model of sensory input (e.g., pixel-level features) by learning to predict representations of the input across parallel streams, resulting in an encoder-only learning and inference scheme. This formulation notably rests on active inference (in the form of sensory glimpsing) to drive the learning of representations, i.e., the representational dynamics are driven by sequences of decisions made by the model to sample informative portions of its sensorium.
Mar 3, 2025

Hyperspectral Image Restoration and Super-resolution with Physics-Aware Deep Learning for Biomedical Applications

Hyperspectral imaging is a powerful bioimaging tool which can uncover novel insights, thanks to its sensitivity to the intrinsic properties of materials. However, this enhanced contrast comes at the cost of system complexity, constrained by an inherent trade-off between spatial, spectral, and temporal resolution. To overcome this limitation, we present a self-supervised deep learning-based approach that restores and enhances pixel resolution post-acquisition without requiring external training data beyond the images to be restored. Fine-tuned using metrics aligned with the imaging model, our physics-aware method achieves a 16×\times pixel super-resolution enhancement and a 12×\times imaging speedup without the need of additional training data for transfer learning. Applied to both synthetic and experimental data from five different sample types, including healthy and diseased tissues, we demonstrate that the model preserves biological integrity, as we did not detect systematic loss of biological features or biologically consequential hallucinations in tested datasets. We also concretely demonstrate the model's ability to reveal disease-associated metabolic changes that would otherwise remain undetectable. Furthermore, we provide physical insights into the model's inner workings, paving the way for future refinements that could potentially reveal novel high resolution features in an explainable manner. All methods are available as open-source software on GitHub.
Jan 24, 2025

ACT-JEPA: Novel Joint-Embedding Predictive Architecture for Efficient Policy Representation Learning

Learning efficient representations for decision-making policies is a challenge in imitation learning (IL). Current IL methods require expert demonstrations, which are expensive to collect. Additionally, they are not explicitly trained to understand the environment. Consequently, they have underdeveloped world models. Self-supervised learning (SSL) offers an alternative, as it can learn a world model from diverse, unlabeled data. However, most SSL methods are inefficient because they operate in raw input space. In this work, we propose ACT-JEPA, a novel architecture that unifies IL and SSL to enhance policy representations. It is trained end-to-end to jointly predict 1) action sequences and 2) latent observation sequences. To learn in latent space, we utilize Joint-Embedding Predictive Architecture, which allows the model to filter out irrelevant details and learn a robust world model. We evaluate ACT-JEPA in different environments and across multiple tasks. Our results show that it outperforms the strongest baseline in all environments. ACT-JEPA achieves up to 40% improvement in world model understanding and up to 10% higher task success rate. Finally, we show that predicting latent observation sequences effectively generalizes to predicting action sequences. This work demonstrates how integrating IL and SSL leads to efficient policy representation learning, an improved world model, and a higher task success rate.
Nov 13, 2023

DIRA-SS:Dynamic Domain Incremental Regularised Adaptation -- Self-Supervised

Autonomous systems (AS) often rely on Deep Neural Network (DNN) classifiers to operate in complex and dynamically changing environments. However, during operation, these classifiers may encounter domains that differ from those seen during development, causing performance degradation under distribution shift. Removing systems from operation for labelled data collection and retraining is often impractical, particularly when adaptation must occur quickly and at scale. This paper introduces DIRA-SS, a self-supervised extension of Dynamic Incremental Regularised Adaptation (DIRA) that enables online domain adaptation using only a small number of unlabelled target-domain samples. DIRA-SS augments an existing classifier with an auxiliary retraining branch and adapts the shared feature representation through a rotation-prediction task, while elastic weight consolidation regularises important source-domain parameters to reduce destructive updates. This allows the model to benefit from transfer learning without requiring classification labels during operation. We evaluate DIRA-SS on CIFAR-10C, CIFAR-100C, and ImageNet-C using ResNet architectures under severe common corruptions. The results show that DIRA-SS substantially improves performance over the non-adapted source model, achieves accuracy close to the supervised DIRA method, and outperforms existing unsupervised test-time adaptation baselines on ImageNet-C when using only 100 target-domain samples.
Mar 3, 2022

Structure-Guided Self-Supervised Matching for One-Shot Medical Landmark Detection

Medical landmark detection usually requires accurate expert annotations, which are laborious and difficult to scale across anatomical regions. In this work, we study an extreme annotation-efficient setting where only a single annotated template image is available. We propose SGB-Match, a structure-guided coarse-to-fine self-supervised matching framework for one-shot medical landmark detection. The framework first learns dense anatomical correspondence from unlabeled augmented image pairs, and then transfers the landmark definition from the annotated template to each target image through feature matching. Different from standard contrastive correspondence learning, where negative candidates are penalized by a structure-agnostic rule, we introduce a structure-guided bias into the contrastive objective. The bias is constructed from relative distance and edge-aware anatomical cues, and explicitly reweights the negative gradients: nearby structure-relevant candidates are weakly repelled, while distant or structure-irrelevant negatives are strongly suppressed. As a result, the learned feature space better preserves local anatomical structures around template landmarks and reduces confusing responses from repeated textures. We further adopt a global-to-local design, where a global encoder provides coarse landmark localization and a local encoder refines the prediction in a cropped region. Extensive experiments on four 2D radiological landmark datasets demonstrate that SGB-Match achieves strong one-shot performance across both public and newly collected datasets and consistently benefits from both structure-guided bias and two-stage refinement.