cs.CLOct 20, 2025

Zoom In Disparities in Healthcare LLM Q&A

Authors: Ipek Baris SchlichtBurcu SayinZhixue ZhaoFrederik M. LabontéCesare BarberaMarco VivianiPaolo RossoLucie Flek

Organizations: Universitat Politècnica de València, Valencia, Spain · University of Trento, Trento, Italy · University of Sheffield, Sheffield, UK · Bonn-Aachen International Center for Information Technology, University of Bonn, Bonn, Germany · Lamarr Institute for Machine Learning and Artificial Intelligence, Germany, Dortmund, Germany · University of Pisa, Pisa, Italy · University of Milano-Bicocca, Milano, Italy · ValgrAI Valencian Graduate School and Research Network of Artificial Intelligence, Valencia, Spain

Abstract

Equitable access to reliable health information is vital when integrating AI into healthcare. Yet, information quality varies across languages, raising concerns about the reliability and consistency of multilingual Large Language Models (LLMs). We systematically examine cross-lingual disparities in pre-training source and factuality alignment in LLM answers for multilingual healthcare Q&A across English, German, Turkish, Chinese (Mandarin), and Italian. We (i) constructed Multilingual Wiki Health Care (MultiWikiHealthCare), a multilingual dataset from Wikipedia; (ii) analyzed cross-lingual healthcare coverage; (iii) assessed LLM response alignment with these references; and (iv) conducted a case study on factual alignment through the use of contextual information and Retrieval-Augmented Generation (RAG). Our findings reveal substantial cross-lingual disparities in both Wikipedia coverage and LLM factual alignment. Across LLMs, responses align more with English Wikipedia, even when the prompts are non-English. Providing contextual excerpts from non-English Wikipedia at inference time effectively shifts factual alignment toward culturally relevant knowledge. These results highlight practical pathways for building more equitable, multilingual AI systems for healthcare.

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