Bridging the Skill Gap in Clinical CBCT Interpretation with CBCTRepD

Dento-maxillofacial cone-beam CT (CBCT) reports may contain dozens of tooth-specific, anatomical, and spatial findings from a single 3D scan. Learning to generate such reports from limited clinical data is challenging because routine reports may not exhaustively document image findings, and a non-mention may reflect either absence or non-reporting. We present EviDent-CBCT, an evidence-bottlenecked framework designed for this incomplete supervision. An anatomy-aware network maps each CBCT scan to a discrete record of tooth-level, global, and tooth-IAC evidence. A dental-logic consistency projection reconciles incompatible evidence before a deterministic renderer and an image-blind local language model generate the report using only this record. For tooth-level evidence, reliability-aware training uses eligible non-mentions as reduced-weight negatives, while unreported global and tooth-IAC labels remain unknown. A metal-sensitive input channel preserves intensity cues from dental materials. Across three validation runs, EviDent-CBCT achieves $0.666\pm0.006$ merged evidence set-F1 and $0.402\pm0.003$ RadFact-Lite-Dental logical-F1, versus $0.371\pm0.018$ for the strongest controlled direct baseline. In the ODIN 2026 challenge, it ranked second in automated evaluation and third in blinded clinical Arena comparison on the hidden test set. These results support the discrete evidence record as an effective and auditable interface for CBCT report generation.

Maxillofacial report generation from cone beam computed tomography is scored here by a composite objective placing 80% of its weight on a large language model judgement of factual entailment and 20% on lexical overlap, of which only the lexical fifth is visible during development. The grader's BLEU-4 and METEOR routines are reproduced in pure Python and match the reference to machine precision, and an offline entailment surrogate, which tells a report written for one patient from one written for another at an area under the curve of 0.987, makes the composite objective cheap enough to optimise directly. Over the 622-case public release, a report selected against the visible lexical ranking scores 0.2909, whereas one selected against the composite objective scores 0.4122, because pursuing n-gram overlap drives entailment precision from 0.522 down to 0.266. A 29 million parameter encoder fine-tuned on the release reaches a prevalence-weighted out-of-fold area under the curve of 0.486 over 985 statements, indistinguishable from the corpus prior, while nine numbers read from the image header reach 0.945 for mandible coverage and 0.872 for condyle coverage, and acquisition centre alone predicts sentence choice at 0.718 against 0.663 for the image-derived model, identifying dictation convention rather than anatomy as the quantity the lexical metrics reward. The delivered system emits eight unconditional statements and five gated on header geometry under polarity, laterality and tooth-level consistency constraints, and reaches METEOR 0.3542 over 50 held-out cases from an unseen centre. The dataset and code are available at https://github.com/GIND123/CBCT-Clinical-Reasoner

Interpreting computed tomography (CT) requires review of hundreds of volumetric slices and remains time-intensive and expertise-dependent. Automated CT report generation offers a promising route to improving clinical efficiency, yet the field still lacks a generalizable CT report generation foundation model that supports multi-region reporting and remains robust across external real-world cohorts. Intrinsic inconsistencies in reporting style and diagnostic terminology across cohorts make naive joint training difficult. Here we present Astra, a generalizable CT report generation foundation model developed on 90,678 thoracoabdominal CT-report pairs collected from five sites worldwide (CTRgDB), comprising 353,671 abnormalities spanning eight organ systems. By harmonizing report style and further refining diagnostic consistency via reinforcement learning, Astra achieves style-consistent and diagnostically accurate report generation across diverse anatomical regions and institutions. Evaluated on CTRgDB and six external cohorts, Astra achieves state-of-the-art performance with a 38.4% average improvement in fine-grained diagnostic metrics (P<0.001). Deployed at external clinical sites without any site-specific fine-tuning, Astra accelerated chest report drafting by 29.6% and improved abdominal report completeness by 11.3% among junior and mid-level radiologists (P<0.001). Furthermore, Astra demonstrates broad utility as a foundation for CT AI development, improving downstream diagnostic performance and scaling vision-language pretrain through high-quality report synthesis. Overall, Astra serves as a broadly accessible clinical assistant and a pivotal infrastructure for the next generation of AI-powered healthcare. The code for Astra is publicly available at https://github.com/zh-Wang-Med/Astra.