cs.AIMar 15, 2026

Autonomous Agents Coordinating Distributed Discovery Through Emergent Artifact Exchange

Authors: Fiona Y. Wang, Lee Marom, Subhadeep Pal, Rachel K. Luu, Wei Lu, Jaime A. Berkovich, Markus J. Buehler

Organizations: Laboratory for Atomistic and Molecular Mechanics (LAMM), Massachusetts Institute of Technology, Cambridge, MA 02139, USA · Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA · Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA · Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA · 

Abstract

We present ScienceClaw + Infinite, a framework for autonomous scientific investigation in which independent agents conduct research without central coordination, and any contributor can deploy new agents into a shared ecosystem. The system is built around three components: an extensible registry of over 300 interoperable scientific skills, an artifact layer that preserves full computational lineage as a directed acyclic graph (DAG), and a structured platform for agent-based scientific discourse with provenance-aware governance. Agents select and chain tools based on their scientific profiles, produce immutable artifacts with typed metadata and parent lineage, and broadcast unsatisfied information needs to a shared global index. The ArtifactReactor enables plannerless coordination: peer agents discover and fulfill open needs through pressure-based scoring, while schema-overlap matching triggers multi-parent synthesis across independent analyses. An autonomous mutation layer actively prunes the expanding artifact DAG to resolve conflicting or redundant workflows, while persistent memory allows agents to continuously build upon complex epistemic states across multiple cycles. Infinite converts these outputs into auditable scientific records through structured posts, provenance views, and machine-readable discourse relations, with community feedback steering subsequent investigation cycles. Across four autonomous investigations, peptide design for the somatostatin receptor SSTR2, lightweight impact-resistant ceramic screening, cross-domain resonance bridging biology, materials, and music, and formal analogy construction between urban morphology and grain-boundary evolution, the framework demonstrates heterogeneous tool chaining, emergent convergence among independently operating agents, and traceable reasoning from raw computation to published finding.

Figures & tables

Appendix figures & tables4 assets

Supplementary material from the paper’s appendix.

Appendix

Explore similar work

Feb 23, 2026

From Agent-Only Social Networks to Autonomous Scientific Research: Lessons from OpenClaw and Moltbook, and the Architecture of ClawdLab and Beach.Science

In January 2026, the open-source agent framework OpenClaw and the agent-only social network Moltbook produced a large-scale dataset of autonomous AI-to-AI interaction, attracting six academic publications within fourteen days. This study conducts a multivocal literature review of that ecosystem and presents two complementary platforms for autonomous scientific research as a design science response to the architectural failure modes identified. ClawdLab, an open-source platform for structured laboratory collaboration, addresses these failure modes through hard role restrictions, structured adversarial critique, PI-led governance, multi-model orchestration, and evidence requirements enforced through external tool verification, in which the principal investigator validates submitted work using available API calls, computational services, and model context protocol integrations rather than relying on social consensus. Beach.science, a public research commons, complements ClawdLab's structured laboratory model by providing a free-form environment in which heterogeneous agent configurations interact, discover research opportunities, and autonomously contribute computational analyses, supported by template-based role specialisation, extensible skill registries, and programmatic reward mechanisms that distribute inference resources to agents demonstrating scientific progress. A three-tier taxonomy distinguishes single-agent pipelines, predetermined multi-agent workflows, and fully decentralised systems, analysing why leading AI co-scientist platforms remain confined to the first two tiers. The composable third-tier architecture instantiated across ClawdLab and beach.science, in which foundation models, capabilities, governance, verification tooling, and inter-lab coordination are independently modifiable, enables compounding improvement as the broader AI ecosystem advances.
Jun 29, 2026

Clarus: Coordinating Autonomous Research Agents toward Web-Scale Scientific Collaboration

Existing autonomous research agents can support parts of the research process, but most systems still treat research as either an isolated assistant task or a closed workflow. Therefore, autonomous science needs a collaboration infrastructure that coordinates projects, agents, and digital and physical resources. We identify this as a shift from code-centered execution loops to research-oriented collaboration processes, where questions, evidence, participants, and resources must be coordinated under uncertainty. In this framing, an agent may be an AI system, a human researcher, a team, a laboratory, or an organization-backed participant. To this end, we present Clarus, a collaboration infrastructure for coordinating autonomous research agents toward web-scale scientific collaboration. Clarus reformulates research as an open, auditable, attributable, and resource-aware multi-phase collaboration process. It defines a minimal project-agent-resource object model and organizes scientific collaboration through four layers including Research Application, Digital Collaboration, Physical Substrate, and Physical World. Core modules are implemented as pluggable mechanisms, allowing Clarus to adapt to task risk, collaboration structure, and resource constraints. Through a controlled paper-generation case study, we show that Clarus can organize a research goal into a traceable, reviewable, attributable, and accumulative collaboration network across phases, tasks, and participants. Together, the object model, collaboration protocol, trust mechanisms, and prototype validation provide an initial foundation for open research networks. Clarus is now available at clarus.holosai.io.
Aug 18, 2026

Artifact-centered Claim-aware Observability for Autonomous Scientific Agents

Autonomous scientific agents now increasingly propose ideas, write code, run experiments, analyze results, and even draft papers. Observe and audit those agents are necessary but logging every model call is not enough, scientists also need to inspect the artifacts and claims that the systems produced and their relations. This is driven by the fact that failures in scientific agent systems are often distributed across several objects. A manuscript claim may cite the wrong evidence, a search process may select a degenerate candidate, a laboratory novelty claim may depend on an unstated rule, or a multi-agent plan may change without a visible trigger. Existing tracing, experiment tracking, and archival provenance tools are valuable, but their native objects do not make these scientific audit relations first-class. We argue that autonomous scientific systems should emit portable, claim-aware artifact lineage as a minimum audit layer. We propose a compact observability profile organized around individuals, operators, fitness records, lineage, archives, runs, streams, and steering commands. In this profile, scientific claims are ordinary individuals with explicit evidence bindings and verification records. The profile is intended as a semantic layer that complements current telemetry and provenance standards. Execution details can remain in OpenTelemetry. Final packages can export to PROV-O or RO-Crate standards.