SciCurateBench: Curating Experimental Data from Heterogeneous Scientific Literature with Verbal-Action Agents

Accurately extracting nuanced, contextualized data from research articles is laborious and time intensive. Here, we investigate the performance of frontier, browser-based large language models (LLMs) to extract highly contextualized information. We demonstrate four escalating workflows, 1) given an expert curated prompt and research articles, most frontier LLMs perform well at data extraction, however can struggle with interpreting scientific context and nuance, 2) given simple instructions, LLMs can author their own prompts which were almost as eNective as expert-written prompts, 3) autonomous discovery of research literature was diNicult, agents either missed or hallucinated references, and 4) LLMs can create new datasets from published guidelines that closely match human-expert judges, but still require a human-in-the-loop. Together, these findings define an auditable division of labour in which experts specify the evidence standard, models cross-check repeated extractions and researchers resolve disputed cases, providing a practical route to scaling scientific data curation without relinquishing expert oversight.

Scientific research involves complex information-seeking and reasoning workflows across heterogeneous sources. However, existing benchmarks primarily emphasize general-domain retrieval or static scientific question answering, and therefore fail to assess key capabilities required in realistic scientific research workflows. We introduce SciExplore, a benchmark designed to evaluate scientific information-seeking and reasoning capabilities of LLMs and agents. SciExplore comprises four task types covering 103 expert-curated tasks across more than ten scientific disciplines: scientific database navigation, ambiguous literature retrieval, missing reference completion, and cross-source structured knowledge synthesis, which probe progressively higher-level abilities from entity-level reasoning and document-level identification to evidence-level grounding and domain-level synthesis. We evaluate over ten state-of-the-art LLMs and autonomous agents on SciExplore, revealing substantial performance gaps with performance degrading sharply as task complexity increases and extremely low accuracy on the most challenging structured synthesis tasks. These results highlight significant limitations of current models and agents in realistic scientific information-seeking scenarios.

Reliable automated research requires agents to vet data, verify analyses, and generate hypotheses grounded in trustworthy evidence, potentially reducing routine scientific workload while allowing scientists to focus on interpretation and discovery. Existing benchmarks often only assess analytical task completion or hypothesis generation separately rather than testing whether reliable evidence supports valid and novel claims. We introduce DISCERN (Data Integrity and Scientific Capability: Evidence, Reasoning, and Novelty), a controlled benchmark on real, publicly available datasets that evaluates three key levels of an automated research workflow. The first two levels test data integrity and analysis verification under confounds and tool traps, while the third tests hypothesis generation and revision under adversarial review, including counterfactual cases in which evidence consistent with real data and documented scientific phenomena conflicts with established expectations, motivating alternative explanations and testable hypotheses. Across 203 tasks, eight life-science tracks, and eight models, DISCERN shows that strong aggregate performance can mask level-specific weaknesses. Agents earn perfect scores in only 60.8% of Level 1, 34.2% of Level 2, and 0.6% of Level 3 evaluations, with penalties attributed to rejection of sound data, failure to carry recognized limitations into conclusions, and wide variation in hypothesis production. Cross-track rankings by token and code use are substantially more stable than rankings by evidence judgment, suggesting greater consistency in computational effort than in evidence-based reasoning. These profiles identify opportunities for supervised scientific assistance, but current agents do not yet demonstrate reliable autonomous analysis or discovery. Code and data: https://huggingface.co/datasets/discern-bench-anon/discern-benchmark