AI-Assisted Scientific Research

Overview

The field studies how AI can help across the research process, from finding and synthesizing literature to proposing ideas, analyzing data, writing code, and planning experiments. Common approaches include retrieval-augmented language models, knowledge graphs, tool-using multi-agent systems, and domain-specific models for areas such as chemistry, biology, and astronomy. Evaluation ranges from literature and coding benchmarks to reproducibility tests and prospective laboratory or field studies. AI is often useful for structured, tool-mediated tasks, but open-ended discovery, reliable screening, calibrated uncertainty, and faithful experimental validation remain difficult, making provenance and human oversight central.

Latest papers

CardsList

253 papers25 papers in the last four weeks, down 7% on the four weeks before. 0.1% of all new papers.

  1. AI4EOSC: a Federated Cloud Platform for Artificial Intelligence in Scientific Research

    Dec 18, 2025Ignacio Heredia, Álvaro López García, Fernando Aguilar Gómez +28AI-Assisted Scientific ResearchScientific Workflow Automation

  2. Leveraging Discrete Function Decomposability for Scientific Design

    Nov 4, 2025James C. Bowden, Sergey Levine, Jennifer ListgartenAI-Assisted Scientific ResearchCombinatorial Optimization

  3. STAR-VAE: A Scalable Latent-Variable Transformer for Controllable Molecular Generation

    Nov 4, 2025Bum Chul Kwon, Ben Shapira, Moshiko Raboh +7Molecular OptimizationTransformer

  4. Idea2Plan: Exploring AI-Powered Research Planning

    Oct 28, 2025Jin Huang, Silviu Cucerzan, Sujay Kumar Jauhar +1LLM EvaluationLLM-as-a-Judge

  5. APEX: Approximate-but-exhaustive search for ultra-large combinatorial synthesis libraries

    Oct 28, 2025Aryan Pedawi, Jordi Silvestre-Ryan, Bradley Worley +5Surrogate-Assisted OptimizationAI-Assisted Scientific Research

  6. Towards AI-Assisted Research Writing: Benchmarking LLMs for AI/ML Introduction Generation

    Aug 19, 2025Krishna Garg, Firoz Shaik, Sambaran Bandyopadhyay +1LLM EvaluationLanguage Model Generation Evaluation

  7. A Large Scale Investigation of Scaling Limits in Chemical Language Models

    Aug 19, 2025Roshan Balaji, Kamran Chitsaz, Quentin Fournier +2Chemical Language ModelsLanguage Model Scaling Laws

  8. Large Language Models Transform Organic Synthesis From Reaction Prediction to Automation

    Aug 7, 2025Kartar Kumar, Rajesh Kumar, Nikesh LagunAI-Assisted Scientific ResearchLaboratory Automation

  9. AI Mathematician: Towards Fully Automated Frontier Mathematical Research

    May 28, 2025Yuanhang Liu, Yanxing Huang, Yanqiao Wang +2AI-Assisted Mathematical DiscoveryAI-Assisted Scientific Research

  10. Large language models reshape the language of science

    Apr 10, 2025Dingkang Lin, Naixuan Zhao, Dan Tian +1AI-Assisted Scientific ResearchScientific Communication

  11. MARS: A neurosymbolic approach for interpretable drug discovery

    Oct 2, 2024Lauren Nicole DeLong, Yojana Gadiya, Paola Galdi +2Interpretable MLAI-Assisted Scientific Research

  12. Small Molecule Optimization with Large Language Models

    Jul 26, 2024Philipp Guevorguian, Menua Bedrosian, Tigran Fahradyan +3Molecular OptimizationEvolutionary Optimization

  13. Generating Interesting Scientific Ideas using Knowledge Graphs and LLMs: Evaluations with 100 Research Group Leaders

    May 27, 2024Xuemei Gu, Mario KrennAI-Assisted Scientific ResearchScientific Hypothesis Generation