Efficient Neural Network Inference

Overview

The field studies how to run trained neural networks with less latency, memory, and energy, from phones and microcontrollers to GPUs, FPGAs, and large serving clusters. Common approaches include quantization, pruning, distillation, early exits and conditional computation, alongside compiler and kernel optimization, memory-aware scheduling, and specialized or neuromorphic hardware. Work spans vision, language, graphs, and streaming tasks, with evaluation increasingly measuring end-to-end latency, throughput, and energy on target devices rather than relying only on parameter counts or FLOPs. A central tension is that theoretical savings such as sparsity or fewer operations do not always yield faster real deployments, and efficiency gains must be balanced against accuracy, reliability, and hardware constraints.

Latest papers

471 papers46 papers in the last four weeks, up 7% on the four weeks before. 0.3% of all new papers.

Dec 4, 2025

Hardware-Algorithm Co-Optimization of Early-Exit Neural Networks for Multi-Core Edge Accelerators

The deployment of Early-Exiting Neural Networks (EENNs) on edge accelerators requires optimizing not only the network architecture but also its hardware deployment. Exit configuration, quantization, and hardware workload mapping interact in non-trivial ways, influencing memory traffic, accelerator utilization, and ultimately the energy-latency trade-off. This work presents a hardware-aware co-design framework for EENNs that jointly optimizes exit configuration, quantization-aware training, and multi-core hardware mapping within a unified NAS process. Leveraging analytical design space exploration, the framework identifies efficient workload mappings for each candidate architecture while providing accurate latency and energy estimates during the search. We further formulate EENN deployment as a constrained multi-objective optimization problem balancing predictive accuracy, energy-latency product, exit overhead, and dynamic inference efficiency. Experimental results on CIFAR-10 demonstrate that the proposed framework achieves over a 50% reduction in energy-latency product compared with static baselines under 8-bit quantization. These results demonstrate that jointly optimizing architecture and deployment is essential for realizing the full efficiency potential of dynamic inference on heterogeneous edge accelerators.
Nov 28, 2025

Accelerated Execution of Bayesian Neural Networks using a Single Probabilistic Forward Pass and Code Generation

Machine learning models perform well across domains such as diagnostics, weather forecasting, NLP, and autonomous driving, but their limited uncertainty handling restricts use in safety-critical settings. Traditional neural networks often fail to detect out-of-domain (OOD) data and may output confident yet incorrect predictions. Bayesian neural networks (BNNs) address this by providing probabilistic estimates, but incur high computational cost because predictions require sampling weight distributions and multiple forward passes. The Probabilistic Forward Pass (PFP) offers a highly efficient approximation to Stochastic Variational Inference (SVI) by assuming Gaussian-distributed weights and activations, enabling fully analytic uncertainty propagation and replacing sampling with a single deterministic forward pass. We present an end-to-end pipeline for training, compiling, optimizing, and deploying PFP-based BNNs on embedded ARM CPUs. Using the TVM deep learning compiler, we implement a dedicated library of Gaussian-propagating operators for multilayer perceptrons and convolutional neural networks, combined with manual and automated tuning strategies. Ablation studies show that PFP consistently outperforms SVI in computational efficiency, achieving speedups of up to 4200x for small mini-batches. PFP-BNNs match SVI-BNNs on Dirty-MNIST in accuracy, uncertainty estimation, and OOD detection while greatly reducing compute cost. These results highlight the potential of combining Bayesian approximations with code generation to enable efficient BNN deployment on resource-constrained systems.
Nov 27, 2025

AutoTailor: Automatic and Efficient Adaptive Model Deployment for Diverse Edge Devices

On-device machine learning (ML) has become a fundamental component of emerging mobile applications. Adaptive model deployment delivers efficient inference for heterogeneous device capabilities and performance requirements through customizing neural architectures. SuperNet-based approaches offer a promising solution by generating numerous model variants from a pre-trained ML model. However, applying SuperNet in existing frameworks requires tedious model-aware development and time-consuming hardware-aware profiling, which limits their practical adoption. We present AutoTailor, the first framework to enable automated, end-to-end SuperNet-based adaptive model deployment for edge devices. Unlike manual SuperNet construction, AutoTailor employs a computation graph-guided compilation approach to automatically transform user-provided ML models into SuperNets. To support efficient specialization, AutoTailor incorporates learning-free latency and accuracy predictors, enabling low-cost yet accurate performance prediction. Our extensive evaluations demonstrate that AutoTailor reduces the lines of code for SuperNet construction by 10.8--34.5×\times, reduces predictor profiling time by 2.2--11.5×\times, and achieves up to 15.60% absolute accuracy improvement and 60.03% latency reduction compared to state-of-the-art approaches across diverse models and devices. AutoTailor's source code is publicly available at https://github.com/liu-mengyang/AutoTailor.
Nov 7, 2025

NeuroFlex: Lossless Element-Level ANN-SNN Co-Execution for Efficient Sparse Inference

Sparse DNN accelerators specialize in ANN or SNN execution, leaving energy or latency on the table when workload characteristics vary within a layer. Hybrid accelerator designs that switch modes at layer or tile granularity suffer from low PE utilization since one core type idles whenever the other is active. NeuroFlex is the first accelerator to assign every output element independently to ANN or SNN execution mode with zero accuracy loss. We extend integer-exact ANN-SNN equivalence from layers to individual output elements, thereby enabling mode switching with no conversion error. An offline cost-guided scheduler scores each element by its marginal energy-delay trade-off and packs work across PEs, achieving 97-99% PE utilization compared to 40-45% for layer-wise hybrids. NeuroFlex reduces EDP by 57-67% over a strong ANN-only baseline and delivers up to 2.5x speedup over a dual-sparse SNN-only baseline. Our cost-guided scheduler improves throughput by 16-19% over random element assignment across vision, language, and transformer workloads.
Oct 28, 2025

Time-multiplexed layer reuse for physical neural networks

Physical neural networks (PNNs) are promising candidates for next-generation computing, but existing demonstrations remain several orders of magnitude smaller than modern digital neural networks, whose recent advances have been driven by rapid growth in trainable parameters. This situation resembles the constraints of early digital neural networks, which led to ideas around parameter reuse. We investigate what similarly efficient hardware architectures may look like, focusing specifically on the common bottleneck of slow re-adjustment of the weights in PNNs. We propose the Time-Indexed Deep Alternating Layers Network (TIDAL-Net), which occupies an intermediate regime between recurrent and deep neural networks, specifically aimed at the scales and restrictions of common PNN prototypes. TIDAL-Net leverages the timescale separation found in many PNNs between fast forward dynamics and slowly trainable weights and biases, using layer-by-layer time multiplexing to increase effective depth while limiting implementation cost. Numerical experiments on image classification and natural language processing tasks show that TIDAL-Net improves performance with only minor modifications to conventional PNNs.
Sep 29, 2025

BiHDTrans: binary hyperdimensional transformer for efficient multivariate time series classification

The proliferation of Internet-of-Things (IoT) devices has led to an unprecedented volume of multivariate time series (MTS) data, requiring efficient and accurate processing for timely decision-making in resource-constrained edge environments. Hyperdimensional (HD) computing, with its inherent efficiency and parallelizability, has shown promise in classification tasks but struggles to capture complex temporal patterns, while Transformers excel at sequence modeling but incur high computational and memory overhead. We introduce BiHDTrans, an efficient neurosymbolic binary hyperdimensional Transformer that integrates self-attention into the HD computing paradigm, unifying the representational efficiency of HD computing with the temporal modeling power of Transformers. Empirically, BiHDTrans outperforms state-of-the-art (SOTA) HD computing models by at least 14.47% and achieves 6.67% higher accuracy on average than SOTA binary Transformers. With hardware acceleration on FPGA, our pipelined implementation leverages the independent and identically distributed properties of high-dimensional representations, delivering 39.4 times lower inference latency than SOTA binary Transformers. Theoretical analysis shows that binarizing in holographic high-dimensional space incurs significantly less information distortion than directly binarizing neural networks, explaining BiHDTrans's superior accuracy. Furthermore, dimensionality experiments confirm that BiHDTrans remains competitive even with a 64% reduction in hyperspace dimensionality, surpassing SOTA binary Transformers by 1-2% in accuracy with 4.4 times less model size, as well as further reducing the latency by 49.8% compare to the full-dimensional baseline. Together, these contributions bridge the gap between the expressiveness of Transformers and the efficiency of HD computing, enabling accurate, scalable, and low-latency MTS classification.
Sep 26, 2025

Physics-informed GNN for medium-high voltage AC power flow with edge-aware attention and line search correction operator

Physics-informed graph neural networks (PIGNNs) have emerged as fast AC power-flow solvers that can replace the classic NewtonRaphson (NR) solvers, especially when thousands of scenarios must be evaluated. However, current PIGNNs still need accuracy improvements at parity speed; in particular, the soft constraint on the physics loss is inoperative at inference, which can deter operational adoption. We address this with PIGNN-Attn-LS, combining an edge-aware attention mechanism that explicitly encodes line physics via per-edge biases to form a fully differentiable knownoperator layer inside the computation graph, with a backtracking line-search-based globalized correction operator that restores an operative decrease criterion at inference. Training and testing use a realistic High-/Medium-Voltage scenario generator, with NR used only to construct reference states. On held-out HV cases consisting of 4-32-bus grids, PIGNN-Attn-LS achieves a test RMSE of 0.00033 p.u. in voltage and 0.08 deg in angle, outperforming the PIGNN-MLP baseline by 99.5% and 87.1%, respectively. With streaming micro-batches, it delivers 2-5x faster batched inference than NR on 4-1024-bus grids.
Sep 17, 2025

GraphMend: Code Transformations for Fixing Graph Breaks in PyTorch 2

This paper presents GraphMend, a compiler technique that automatically fixes FX graph breaks in PyTorch 2 programs. Although PyTorch 2 introduced TorchDynamo and TorchInductor to enable just-in-time graph compilation, certain code patterns still cause graph breaks that force execution to fall back to Python eager mode, introducing costly CPU-GPU synchronization and reducing optimization opportunities. Our investigation of 195 Hugging Face models reveals that 13.8% of models exhibit graph breaks. GraphMend automatically eliminates fixable breaks through source-level program analysis and transformations. It analyzes AST-level program structure to identify graph-break patterns and applies transformations only when their semantic preservation can be statically established. These transformations enable PyTorch to capture larger, uninterrupted FX graphs without manual refactoring by developers. We evaluate GraphMend on all 27 models found to exhibit graph breaks in our investigation. GraphMend eliminates 107 of 147 graph breaks (73%), fully fixing all breaks in 21 models. In our experiments on NVIDIA GPUs, GraphMend achieves up to 26x cold-start speedup, 5x on average, and up to 1.39x steady-state forward pass speedup. These results demonstrate that semantics-aware source-level analysis and transformation are effective complements to PyTorch's dynamic JIT compilation pipeline, substantially improving both usability and performance.
Sep 1, 2025

Practical and Private Hybrid ML Inference with Fully Homomorphic Encryption

In contemporary cloud-based services, protecting users' sensitive data and ensuring the confidentiality of the server's model are critical. Fully homomorphic encryption (FHE) enables inference directly on encrypted inputs, but its practicality is hindered by expensive bootstrapping and inefficient approximations of non-linear activations. We introduce Safhire, a hybrid inference framework that executes linear layers under encryption on the server while offloading non- linearities to the client in plaintext. This design eliminates bootstrapping, supports exact activations, and significantly reduces computation cost. To safeguard model confidentiality despite client access to intermediate outputs, Safhire applies randomized shuffling, which obfuscates intermediate values and makes it practically impossible for a client to reconstruct the model. To further reduce inference latency, Safhire incorporates advanced optimizations such as fast ciphertext packing and partial extraction. Evaluations on multiple standard models and datasets show that Safhire achieves up to 7.6x and 7.4x lower inference latency than Orion and Concrete-ML, respectively, which are two state-of-the-art FHE baselines, with manageable communication overhead and comparable accuracy. These results underline the practicality of our hybrid FHE inference scheme.
Aug 15, 2025

Visual Perception Engine: Fast and Flexible Multi-Head Inference for Robotic Vision Tasks

Deploying multiple machine learning models on resource-constrained robotic platforms for different perception tasks often results in redundant computations, large memory footprints, and complex integration challenges. In response, this work presents Visual Perception Engine (VPEngine), a modular framework designed to enable efficient GPU usage for visual multitasking while maintaining extensibility and developer accessibility. Our framework architecture leverages a shared foundation model backbone that extracts image representations, which are efficiently shared, without any unnecessary GPU-CPU memory transfers, across multiple specialized task-specific model heads running in parallel. This design eliminates the computational redundancy inherent in feature extraction component when deploying traditional sequential models while enabling dynamic task prioritization based on application demands. We demonstrate our framework's capabilities through an example implementation using DINOv2 as the foundation model with multiple task (depth, object detection and semantic segmentation) heads, achieving up to 3x speedup compared to sequential execution. Building on CUDA Multi-Process Service (MPS), VPEngine offers efficient GPU utilization and maintains a constant memory footprint while allowing per-task inference frequencies to be adjusted dynamically during runtime. The framework is written in Python and is open source with ROS2 C++ (Humble) bindings for ease of use by the robotics community across diverse robotic platforms. Our example implementation demonstrates end-to-end real-time performance at ≥\geq50 Hz on NVIDIA Jetson Orin AGX for TensorRT optimized models.
Jul 30, 2025

Adaptive Time-step Training for Enhancing Spike-Based Neural Radiance Fields

Spiking Neural Networks (SNNs) provide an energy-efficient computing paradigm for neural rendering, but existing spike-based Neural Radiance Field (NeRF) models usually use a fixed inference time step for all scenes. This fixed temporal budget is inefficient because NeRF follows a scene-specific training paradigm, and different scenes require different temporal capacities to preserve rendering quality. This paper proposes Pretraining-based Adaptive Time-step Adjustment (PATA), a scene-wise adaptive time-step training framework for spike-based NeRF. PATA parameterizes the target inference time step as a trainable variable and optimizes it through a two-stage training process. A hybrid input mode strengthens early time-step outputs, while full-step soft supervision, smoothed rendering loss, and temporal-budget loss jointly maintain rendering fidelity and reduce temporal computation. The learned target time step is shared by all ray samples within a scene, preserving the parallel rendering structure of NeRF. Experiments on INGP-NeRF and TensoRF backbones across Synthetic-NeRF, Mip-NeRF 360, and LLFF show that PATA consistently reduces inference cost while maintaining competitive rendering quality. PATA reduces the estimated inference energy by up to 57.57% on INGP-NeRF and 68.90% on TensoRF, demonstrating its effectiveness across different neural rendering representations.
Jul 28, 2025

Efficient Memristive Spiking Neural Networks Architecture with Supervised In-Situ STDP Method

Memristor-based Spiking Neural Networks (SNNs) with temporal spike encoding enable ultra-low-energy computation, making them ideal for battery-powered intelligent devices. This paper presents a circuit-level memristive spiking neural network (SNN) architecture trained using a proposed novel supervised in-situ learning algorithm inspired by spike-timing-dependent plasticity (STDP). The proposed architecture efficiently implements lateral inhibition and the refractory period, eliminating the need for external microcontrollers or ancillary control hardware. All synapses of the winning neurons are updated in parallel, enhancing training efficiency. The modular design ensures scalability with respect to input data dimensions and output class count. The SNN is evaluated in LTspice for pattern recognition (using 5x3 binary images) and classification tasks using the Iris and Breast Cancer Wisconsin (BCW) datasets. During testing, the system achieved perfect pattern recognition and high classification accuracies of 99.11% (Iris) and 97.9% (BCW). Additionally, it has demonstrated robustness, maintaining an average recognition rate of 93.4% under 20% input noise. The impact of stuck-at-conductance faults and memristor device variations was also analyzed.
Jul 2, 2025

evMLP: An Efficient Event-Driven MLP Architecture for Vision

While CNNs and ViTs dominate vision architectures, all-MLP models offer a structurally simpler alternative whose patch-independent processing is naturally suited to exploiting temporal redundancy in video. We present evMLP, an all-MLP architecture that processes image patches independently, enabling an event-driven local update mechanism for video processing: by defining inter-frame changes as "events" and processing only the patches where events occur, evMLP avoids redundant computation on unchanged regions. Because each patch is processed independently, skipping an unchanged patch leaves all other outputs unaffected; at an event threshold of zero, the mechanism produces outputs identical to the dense baseline rather than an approximation. On ImageNet, evMLP achieves 73.5% top-1 accuracy at 1.03 GMACs (rising to 77.0% with knowledge distillation and an extended training schedule). On multiple video datasets, the event-driven mechanism reduces computational cost by 8.4%-26.8% while maintaining output consistency with the dense baseline. Wall-clock measurements confirm that these savings translate into actual speedup under compute-bound conditions, and that stream-level parallelism is the effective deployment strategy for multi-core systems. The code and pre-trained models are available at https://github.com/i-evi/evMLP.
Jul 2, 2025

PERTINENCE: Input-based Opportunistic Neural Network Dynamic Execution

Deep neural networks (DNNs) are widely used for their ability to model complex patterns across domains such as computer vision, speech recognition, and robotics. However, larger models, while often more accurate, are computationally expensive and energy-intensive. Since such a cost is typically needed only for challenging inputs, dynamically selecting lighter models for simpler inputs can improve efficiency with minimal impact on accuracy. We introduce PERTINENCE, a runtime method that selects, from a set of pre-trained models, the lightest model likely to process each input correctly. An ML-based dispatcher performs this selection, and a genetic algorithm explores dispatcher training strategies to identify Pareto-optimal trade-offs between accuracy and computational cost. We evaluate PERTINENCE on CNNs trained on CIFAR-10 and CIFAR-100, ViTs trained on TinyImageNet, and a YOLO-based road occupancy estimation application using real-time intersection camera feeds. Results show that PERTINENCE matches or improves the accuracy of state-of-the-art pre-trained models while reducing operations by up to 36%, with equivalent or lower end-to-end inference time through tunable invocation intervals.
May 29, 2025

Learning Interpretable Differentiable Logic Networks for Tabular Regression

Neural networks (NNs) achieve outstanding performance in many domains; however, their decision processes are often opaque and their inference can be computationally expensive in resource-constrained environments. We recently proposed Differentiable Logic Networks (DLNs) to address these issues for tabular classification based on relaxing discrete logic into a differentiable form, thereby enabling gradient-based learning of networks built from binary logic operations. DLNs offer interpretable reasoning and substantially lower inference cost. We extend the DLN framework to supervised tabular regression. We first redesign the final output layer (the SumLayer) to support continuous targets. More critically, we find the original two-phase training procedure used for classification is suboptimal for regression, and thus develop a unified, single-stage optimization procedure. We also demonstrate that temperature annealing of the network's differentiable relaxations is decisive for achieving stable convergence and high accuracy. We evaluate the resulting model on 15 public regression benchmarks, comparing it with modern neural networks and classical regression baselines. Regression DLNs match or exceed baseline accuracy while preserving interpretability and fast inference. Our results show that DLNs are a viable, cost-effective alternative for regression tasks, especially where model transparency and computational efficiency are important.
May 20, 2025

Optimizing Binary and Ternary Neural Network Inference on RRAM Crossbars using CIM-Explorer

Using Resistive Random Access Memory (RRAM) crossbars in Computing-in-Memory (CIM) architectures offers a promising solution to overcome the von Neumann bottleneck. Due to non-idealities like cell variability, RRAM crossbars are often operated in binary mode, utilizing only two states: Low Resistive State (LRS) and High Resistive State (HRS). Binary Neural Networks (BNNs) and Ternary Neural Networks (TNNs) are well-suited for this hardware due to their efficient mapping. Existing software projects for RRAM-based CIM typically focus on only one aspect: compilation, simulation, or Design Space Exploration (DSE). Moreover, they often rely on classical 8 bit quantization. To address these limitations, we introduce CIM-Explorer, a modular toolkit for optimizing BNN and TNN inference on RRAM crossbars. CIM-Explorer includes an end-to-end compiler stack, multiple mapping options, and simulators, enabling a DSE flow for accuracy estimation across different crossbar parameters and mappings. CIM-Explorer can accompany the entire design process, from early accuracy estimation for specific crossbar parameters, to selecting an appropriate mapping, and compiling BNNs and TNNs for a finalized crossbar chip. In DSE case studies, we demonstrate the expected accuracy for various mappings and crossbar parameters. CIM-Explorer can be found on GitHub.
May 9, 2025

Sigma-Delta Neural Network Conversion on Loihi 2

Neuromorphic computing aims to improve the efficiency of artificial neural networks by taking inspiration from biological neurons and leveraging temporal sparsity, spatial sparsity, and compute near/in memory. Although these approaches have shown efficiency gains, training these spiking neural networks (SNN) remains difficult. The original attempts at converting trained conventional analog neural networks (ANN) to SNNs used the rate of binary spikes to represent neuron activations. This required many simulation time steps per inference, which degraded efficiency. Intel's Loihi 2 is a neuromorphic platform that supports graded spikes which can be used to represent changes in neuron activation. In this work, we use Loihi 2's graded spikes to develop a method for converting ANN networks to spiking networks, which exploits temporal and spatial sparsity. We evaluated the performance of this network on Loihi 2 and compared it to NVIDIA's Jetson Xavier edge AI platform. The results show that neuromorphic approaches achieve significant improvements in efficiency and latency (energy-delay product) over existing solutions.
Apr 28, 2025

Leveraging Neural Graph Compilers in Machine Learning Research for Edge-Cloud Systems

This work presents a comprehensive evaluation of neural network graph compilers across heterogeneous hardware platforms, addressing the critical gap between theoretical optimization techniques and practical deployment scenarios. We demonstrate how vendor-specific optimizations can invalidate relative performance comparisons between architectural archetypes, with performance advantages sometimes completely reversing after compilation. Our systematic analysis reveals that graph compilers exhibit performance patterns highly dependent on both neural architecture and batch sizes. Through fine-grained block-level experimentation, we establish that vendor-specific compilers can leverage repeated patterns in simple architectures, yielding disproportionate throughput gains as model depth increases. We introduce novel metrics to quantify a compiler's ability to mitigate performance friction as batch size increases. Our methodology bridges the gap between academic research and practical deployment by incorporating compiler effects throughout the research process, providing actionable insights for practitioners navigating complex optimization landscapes across heterogeneous hardware environments.
Mar 21, 2025

Echo-E3^3Net: Efficient Endocardial Spatio-Temporal Network for Ejection Fraction Estimation

Left ventricular ejection fraction (LVEF) is a primary marker of cardiac function. However, routine estimation from endocardial measurements requires manual delineation at end-diastole (ED) and end-systole (ES), a process that is time-consuming and subject to inter-observer variability. Reliable automation is especially valuable for point-of-care ultrasound (POCUS), where computational resources are limited and acquisition quality varies. We propose Echo-E3^3Net, an anatomy-guided spatio-temporal network that explicitly embeds cardiac anatomy into LVEF prediction. A dual-phase Endocardial Border Detector (E2^2CBD) uses phase-specific cross-attention to localize ED/ES endocardial landmarks and produce phase-aware landmark embeddings, while an Endocardial Feature Aggregator (E2^2FA) fuses these embeddings with global statistical descriptors of deep feature maps to refine EF regression. Training is guided by a lightweight geometric loss that uses ED and ES endocardial landmarks to regularize EF prediction. On EchoNet-Dynamic and a PSAX subset of EchoNet-Pediatric, Echo-E3^3Net attains competitive performance using only 1.55M parameters and 8.05 GFLOPs, an order-of-magnitude compute reduction versus recent baselines, supporting real-time deployment. Our code is publicly available at https://github.com/moeinheidari7829/Echo-E3Net.
Jan 15, 2025

Reforge: Low-Latency Distributed GNN Serving with Selective Embedding Recomputation

Graph Neural Networks (GNNs) have been widely adopted for their ability to compute expressive node representations in graph datasets. However, serving GNNs on large graphs is challenging due to the high communication, computation, and memory overheads of constructing and executing computation graphs, which represent information flow across large neighborhoods. Existing approximation techniques in training can mitigate the overheads but, in serving, still lead to high latency and/or accuracy loss. To this end, we propose Reforge, a system that enables low-latency GNN serving for large graphs with minimal accuracy loss through two key ideas. First, Reforge employs selective recomputation of precomputed embeddings, which allows for reusing precomputed computation subgraphs while selectively recomputing a small fraction to minimize accuracy loss. Second, we develop computation graph parallelism, which reduces communication overhead by parallelizing the creation and execution of computation graphs across machines. Our evaluation with large graph datasets and GNN models shows that Reforge significantly outperforms state-of-the-art techniques.
Feb 6, 2024

FlowWise: Stateful Fast-Slow Model Serving for Streaming Traffic Intelligence

Network traffic analysis in cloud and internet service provider (ISP) networks increasingly relies on machine learning (ML) models, as encryption and service consolidation make rule-based classification unreliable. At high flow-arrival rates, however, new flows can arrive faster than end-to-end analysis pipelines can process. Unlike typical cloud inference workloads, packets from the same flow arrive over time and require per-flow state. This streaming, stateful setting limits naive scale-out with stateless workers. This paper presents FlowWise, a serving system for streaming, stateful flow intelligence on commodity CPU/GPU servers that jointly selects (i) how many packets to collect and (ii) which model(s) to apply for each flow to balance latency, service rate, and accuracy. Across three representative tasks, inference time across candidate models differs by 1.8x-141.3x, while packet waiting time can exceed feature computation and inference by 6-8 orders of magnitude at the tail. FlowWise exploits these gaps with an uncertainty-driven fast-slow cascade: it issues early predictions from a one-packet model and escalates only uncertain flows to slower models that wait for additional packets and use richer features. A queue-centric runtime maintains per-flow state, performs asynchronous feature joining, and uses brokered, flow-ID-keyed streams to distribute workload across heterogeneous workers. FlowWise serves 76.3% of flows within 16 ms, improving median end-to-end serving latency by 40.5x while increasing service rate and maintaining similar accuracy to always running the slow model. With thousands of packet-header features per flow, our scale-up benchmark sustains over 48.5k new flows per second on a single 16-core commodity CPU server, comparable to reported flow-arrival rates in city-backbone traces. FlowWise is open sourced at https://github.com/noise-lab/FlowWise.