NeRFscopy: Neural Radiance Fields for in-vivo Time-Varying Tissues from Endoscopy

Reconstructing dynamic surgical scenes is crucial for robot-assisted minimally invasive surgery; however, it continues to be difficult because of tissue deformation, occlusions, specular reflections, and restricted viewpoints. In this study, we introduce Endo-NeRF++, a neural rendering framework that accounts for uncertainty in the reconstruction of dynamic surgical scenes. Expanding on EndoNeRF, the suggested approach incorporates multi-resolution hash-grid encoding, temporal feature merging, and uncertainty-informed adaptive sampling to enhance reconstruction accuracy and temporal coherence in deformable endoscopic scenes.The multi-resolution hash-grid representation within the framework effectively captures both coarse and fine anatomical details, while temporal feature blending ensures stable reconstruction during tissue deformation and surgical tool occlusions. Additionally, uncertainty-driven adaptive sampling assigns more samples to uncertain areas to enhance rendering quality and geometric coherence. Experiments on robotic surgical video sequences demonstrate that the proposed uncertainty-guided adaptive sampling improves PSNR by up to 1.22dB (4.3%), increases SSIM by up to 5.3%, and reduces LPIPS by up to 55.1% compared with the EndoNeRF baseline.

Reconstructing deformable surgical scenes from endoscopic videos is challenging and clinically important. Recent state-of-the-art methods based on implicit neural representations or 3D Gaussian splatting have made notable progress. However, most are designed for deformable scenes with fixed endoscope viewpoints and rely on stereo depth priors or accurate structure-from-motion for initialization and optimization, limiting their ability to handle monocular sequences with large camera motion in real clinical settings. To address this, we propose Local-EndoGS, a high-quality 4D reconstruction framework for monocular endoscopic sequences with arbitrary camera motion. Local-EndoGS introduces a progressive, window-based global representation that allocates local deformable scene models to each observed window, enabling scalability to long sequences with substantial motion. To overcome unreliable initialization without stereo depth or accurate structure-from-motion, we design a coarse-to-fine strategy integrating multi-view geometry, cross-window information, and monocular depth priors, providing a robust foundation for optimization. We further incorporate long-range 2D pixel trajectory constraints and physical motion priors to improve deformation plausibility. Experiments on three public endoscopic datasets with deformable scenes and varying camera motions show that Local-EndoGS consistently outperforms state-of-the-art methods in appearance quality and geometry. Ablation studies validate the effectiveness of our key designs. Code will be released upon acceptance at: https://github.com/IRMVLab/Local-EndoGS.

Robot-assisted minimally invasive surgery (MIS) critically depends on reliable endoscopic perception for navigation and safety. However, conventional endoscopes provide only a limited field of view, leaving large portions of the surrounding anatomy unobserved. Recent neural rendering approaches, such as Neural Radiance Fields and 3D Gaussian Splatting, enable novel view synthesis from endoscopic videos, but their reliance on sparse observations often leads to severe artifacts when extrapolating beyond the training trajectory. In this work, we propose ExtraGS, a framework for enhancing endoscopic view extrapolation through diffusion-guided 3D Gaussian Splatting. Starting from an initial reconstruction, we introduce an uncertainty-guided virtual camera sampling strategy to actively explore blind spots and maximize information gain. The rendered views from these sampled locations are refined using a diffusion model to recover plausible anatomical structures, producing pseudo-observations that guide further optimization. To prevent the generated content from degrading reliable regions, we adopt a confidence-weighted fine-tuning strategy when incorporating these pseudo-observations. Extensive experiments on multiple public endoscopic datasets demonstrate that ExtraGS significantly reduces extrapolation artifacts and achieves state-of-the-art performance in endoscopic novel view synthesis.