Organizations: Institute of Information Engineering, Chinese Academy of Sciences, Beijing, China · School of Cyber Security, University of Chinese Academy of Sciences, Beijing, China · Culverhouse College of Business, The University of Alabama, Tuscaloosa, AL, USA · Business Administration, Chang’an University, Xi’an, Shaanxi, China
While online medical consultation broadens access, unprompted patient disclosures and topic shifts frequently disrupt clinician inquiry, leaving clinical states progressively revealed. We characterize these dynamics using both existing evaluation metrics and task-specific interaction metrics designed in this work. Through an empirical study across 16 medical dialogue datasets, we show that authentic online interactions exhibit substantially lower contextual continuity and higher unpredictability than offline and simulated benchmarks. We propose PRISM (Policy Reasoning with Inferred States for Medicine), a framework inspired by partially observable Markov decision processes that decouples latent state estimation from action selection to address drifting dialogue trajectories. Specifically, PRISM factorizes clinical triage into belief estimation, policy optimization, and response realization. By maintaining an evolving posterior belief over consultation states and conditioning action selection on the maximum a posteriori state, PRISM advances clinical goals while accommodating patient-initiated shifts. Extensive evaluations show that PRISM substantially outperforms frontier LLMs and clinical agents, achieving a 22.40 percentage point gain in clinical decision accuracy alongside decisive improvements in response generation, surpassing the strongest baseline by 5.51 points in BERTScore_F1. Furthermore, ablation studies show that providing oracle consultation states consistently boosts response quality across all evaluated baselines by guiding their action reasoning, yielding average gains of 5.58 points in BERTScore_F1.
Figures & tables
Attributes
Samples used
Utterance
Discourse (Patient)
Discourse (Physician)
Corpus
Dataset
Type
Mode
Dial.
Utt.
ECoh ↓
BPB ↑
Discl. ↑
Redir. ↑
Any ↑
Cond. ↑
Colla. ↑
MAUVE ↑
MedSynth
Sim.
Off.
5.00k
242.38k
0.924
/
0.044
0.007
0.050
0.375
0.019
/
ACI-Bench
Sim.
Off.
0.21k
11.21k
0.809
/
0.079
0.013
0.086
0.387
0.034
/
MediTOD
Sim.
Off.
0.21k
20.31k
0.905
/
0.079
0.003
0.081
0.457
0.035
/
NoteChat
Sim.
Off.
5.00k
142.90k
0.903
/
0.088
0.005
0.091
0.432
0.040
/
MDD-5k ∗
Sim.
Off.
4.63k
214.36k
0.932
0.761
0.168
0.004
0.168
0.256
0.043
0.005
Table 1. Interaction dynamics of the evaluated samples (rates in [0,1] , BPB in bits/byte). ∗ denotes Chinese corpora. Arrows indicate support directions. Shaded rows report group means.
Figure 1. Overview of PRISM. Overview of PRISM.
Model
EM
ROUGE-1
ROUGE-2
ROUGE-L
BLEU-4
chrF
Sem.
BertScore P
BertScore R
BertScore F1
Qwen3.8-27B
0.00
22.07
8.53
18.88
3.07
8.52
58.96
61.97
73.44
67.12
Qwen3.8-Max
0.00
21.55
8.53
18.54
3.28
8.87
59.03
61.35
73.30
66.71
DeepSeek-V4-Pro
0.00
22.76
9.46
19.72
3.48
9.32
59.01
61.79
73.63
67.10
MiniMax-M3
0.00
22.03
9.37
19.27
3.40
9.38
59.49
60.65
73.17
66.23
GPT-6-Astra
0.04
21.00
8.57
17.96
2.93
8.59
58.62
60.06
72.63
65.65
Codex
0.00
23.30
8.92
19.85
3.61
9.21
60.05
62.43
73.71
67.53
Table 2. Next-question generation performance of PRISM and baseline systems.
Model
Acc. ↑
Recall ↑
Precision ↑
F1 ↑
Qwen3-8B-SFT
43.07
43.07
47.88
40.95
Qwen3.8-27B
46.19
46.19
51.70
44.40
Qwen3.8-Max
51.76
51.76
60.68
48.31
DeepSeek-V4-Pro
53.65
53.65
60.18
51.82
MiniMax-M3
53.99
53.99
60.44
51.68
GPT-6-Astra
50.98
50.98
58.58
48.24
Table 3. Clinical decision performance.
Figure 2. Response generation with and without oracle state policy guidance. Labels indicate score gains. Response generation with and without oracle state policy guidance. Labels indicate score gains.
School of Computing, National University of Singapore, Singapore · School of Artificial Intelligence, Beihang University, Beijing, China · Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China +1