Gene Expression Data
Gene expression data analysis aims to understand how genes are activated and deactivated within cells, revealing insights into biological processes and disease mechanisms. Current research heavily utilizes machine learning, employing graph neural networks, transformer models, and various contrastive learning approaches to analyze complex relationships within and between gene expression datasets, often integrating this data with other omics data or spatial information. These advancements improve disease classification, biomarker identification, and drug repurposing, offering significant potential for personalized medicine and a deeper understanding of biological systems.
Papers
Human Age Estimation from Gene Expression Data using Artificial Neural Networks
Salman Mohamadi, Gianfranco. Doretto, Nasser M. Nasrabadi, Donald A. Adjeroh
An Information-Theoretic Framework for Identifying Age-Related Genes Using Human Dermal Fibroblast Transcriptome Data
Salman Mohamadi, Donald Adjeroh