Active Feature Acquisition

Active Feature Acquisition (AFA) is a classification problem in which an agent decides which costly features to acquire before predicting each sample's label. Unlike batch AFA, which trains a fixed policy and classifier offline on fully observed data, online AFA updates its predictor from revealed labels as samples arrive. Existing online methods either use deep reinforcement learning (RL) without performance guarantees or maximize cost-adjusted reward rather than enforce a global budget. We formulate online AFA as a combinatorial Bandits with Knapsacks (BwK) problem that couples acquisition and prediction. Unlike prior bandit-based AFA and classical BwK, our setting has combinatorial complexity, evolving rewards, a global budget, and structured side information. We obtain an improved regret upper bound over standard BwK bounds in this framework, leveraging a cardinality-aware confidence bound and the subset update structure. To avoid an exponentially large action space, we propose \emph{LP-Chain}, a variant that searches a cost-aware chain of feature subsets with a size that grows linearly with the number of features. While the regret upper bound is specific to the combinatorial framework, \emph{LP-Chain} empirically achieves comparable predictive performance. On synthetic data, \emph{LP-Chain} outperforms HEDGE-based BwK and deep RL-based online AFA baselines and scales favorably to more features.

Accurate forecasting of pathological outcomes is a central problem in psychology. To do so, psychologists often collect intensive longitudinal data. However, in such studies, the desire to acquire a large number of variables for the sake of accurate prediction is often counteracted by the need to minimize participant burden. Acquiring more variables per occasion can yield better predictions, but having too many acquisitions increase the risk of non-response and attrition. Longitudinal Active Feature Acquisition (LAFA) is a principled approach to resolve this conundrum. Instead of requiring responses to every item at every acquisition occasion, LAFA produces a policy that seeks to optimally select dynamic subsets of items to be acquired at each timepoint while preserving our ability to forecast a specific outcome. However, existing LAFA methods are mostly based on Neural Networks (NN) that are difficult to interpret in practice. In this work, we introduce a tree distillation method for learning an interpretable policy from NN-based LAFA networks. We validated our method through both a simulation and an empirical EMA dataset on forecasting daily alcohol consumption. In both cases, we find that we can meaningfully reduce the number of items acquired at each occasion with minimal loss in accuracy. Networks (NN) that are difficult to interpret in practice. In this work, we introduce a tree distillation method for learning an interpretable policy from NN-based LAFA networks. We validated our method through both a simulation and an empirical EMA dataset on forecasting daily alcohol consumption. In both cases, we find that we can meaningfully reduce the number of items acquired at each occasion with minimal loss in accuracy.

Active feature acquisition learns policies that sequentially acquire features to maximize information about a target variable. We study how to learn and evaluate such policies from finite offline data using prior-data fitted networks (PFNs), which are off-the-shelf models that output posterior predictive distributions without task-specific training. We show that under the imbalanced coverage of offline data, using total predictive entropy as a reward creates an epistemic bias that penalizes acquiring sparsely observed features. Specifically, this reward conflates epistemic uncertainty (arising from lack of offline data) with aleatoric uncertainty (arising from uninformative features). To address this, we target the posterior expected (aleatoric) entropy instead of the total predictive entropy output by a PFN for evaluating feature acquisitions. Empirical evaluations on synthetic and real-world datasets demonstrate that our approach consistently reduces value estimation bias and yields credible intervals with strong empirical coverage, which can translate to improved downstream policy selection.

More than 300 million people worldwide are affected by one of over 7,000 known rare diseases, yet diagnosis remains difficult because patients initially present with incomplete and heterogeneous phenotypes. We present HPOQuest, a training-free framework for sequential phenotype acquisition in rare-disease diagnosis. Starting from a small set of observed patient phenotypes, HPOQuest maintains a probabilistic disease ranking and iteratively selects informative follow-up questions to support clinicians during patient assessment. Confirmed phenotypes update the disease ranking, while all responses update the candidate question set. Across four benchmark cohorts, HPOQuest substantially improves diagnosis from sparse initial phenotypes, with gains of up to 30% points at Recall@1 and 45% points at Recall@5. These results demonstrate that sequential phenotype acquisition can substantially improve rare-disease diagnosis from limited initial clinical evidence.

Algorithmic recourse methods typically assume that a predictive model has access to all features of an individual. In practice, decisions are often made with partial information, because features are costly to acquire. Active feature acquisition addresses cost-constrained prediction, but existing methods are explanation-agnostic: prior work provides explanations only after acquiring additional features, rather than using explanations to drive acquisition. This work flips that and treats algorithmic recourse and feature acquisition jointly. We use Markov Blanket theory to unify counterfactual, semifactual, and alterfactual explanations and to characterize how available recourse grows as features are acquired. Building on this framework, we propose an Explanation-Driven Feature Acquisition (EDFA) method that selects features by explanatory value per unit cost. The framework is further extended with distribution-free validity guarantees for recourse issued from partial information, which signal trustworthy, lower-cost recourse, along with a lower bound on the calibration data required to certify them. Experiments on 7 publicly available datasets with neural network-based predictive models show that EDFA acquires substantially fewer features than state-of-the-art AFA baselines while maintaining comparable accuracy and yielding more decision-relevant, actionable recourse. The implementation is available on GitHub.

Active feature acquisition (AFA) asks which unobserved feature to measure next for each test instance under a budget. Greedy rules are easy to train but can overlook context features whose value is realized only through later acquisitions, while reinforcement-learning and generative approaches introduce difficult optimization or conditional-density estimation. We introduce \method, a deployable, supervised alternative that learns a separate candidate-conditioned risk-to-go function for every remaining budget. Starting from the one-step terminal classification risk, the functions are fitted backward with Bellman targets; inference greedily minimizes the learned terminal risk using only observed values, the mask, candidate identity, and remaining budget. A controlled non-myopic benchmark shows the expected mechanism: at budgets two and three, \method improves accuracy over its one-step ablation by $4.84\pm2.17$ and $4.39\pm1.10$ percentage points (mean $\pm$ standard error over five seeds). On Fashion-MNIST with 20 candidate pixels, it improves accuracy at every nontrivial reported budget on average, including $10.20\pm0.74$ points at four acquisitions; its mean paired gain across budgets $\{2,4,8,12,16\}$ is $3.50\pm0.37$ points. A three-seed MiniBooNE study is mixed at small budgets but positive at 8 and 16 acquisitions, identifying a current boundary rather than supporting a universal claim. These results establish a reproducible mechanism-level case for direct Bellman risk regression and delimit the experiments still needed for state-of-the-art comparison.

Active feature acquisition (AFA) sequentially selects which features to observe to reach a classification or ranking decision. Its central limitation is reliance on large amount of labeled data to fit probabilistic models guiding acquisition. Large language models (LLMs) supply unsupervised domain knowledge, but are poor sequential planners. Asking one to both know and decide conflates capabilities best kept separate. Here, we develop a framework for zero-shot AFA through disciplined elicitation: asking the LLM only for what it can be trusted to return, the unary deviations and pairwise co-variations that are the sufficient statistics of a Markov random field (MRF). We apply our framework to two settings: binary classification and top-$k$ identification. In practice, the LLM reliably returns only discriminative statistics, what distinguishes the classes rather than each class in isolation, which precludes classical AFA. We apply a maximum-entropy closure that resolves this gauge ambiguity. We evaluate on a cohort of Inflammatory Bowel Disease (IBD) patients, an active clinical setting where diagnostic ambiguity and patient heterogeneity obstruct stable treatment strategies. Our framework outperforms the LLM both on real labels and on its own extracted beliefs. Where it matters most, on the hardest patients, our top-$k$ acquisition policy markedly outperforms all existing methods.

Order-Agnostic autoregressive models have demonstrated strong performance in deep generative modeling, yet their use in settings with incomplete data remains largely unexplored. In this work, we reinterpret them through the lens of missing data. First, we show that their standard training procedure on fully observed data implicitly performs imputation under a missing completely at random mechanism, resulting in robust out-of-sample imputation performance in settings with high missingness. Second, we introduce the first principled framework for training them directly on incomplete datasets under general missingness mechanisms. Third, we leverage their amortized conditional density estimation to perform active information acquisition, i.e., sequentially selecting the most informative missing variables for downstream prediction or inference. Across a suite of real-world benchmarks, our Missingness-Aware Order-Agnostic Autoregressive Model (MO-ARM) consistently outperforms established imputation baselines.

Active feature acquisition (AFA) considers prediction problems in which features are costly to obtain and the learner adaptively decides which feature values to acquire for each instance and when to stop and predict. AFA can be formulated as a partially observable Markov decision process (POMDP), which naturally admits a sequential decision-making perspective. In this paper, we present non-myopic pathwise policy gradients (NM-PPG), a new AFA method built around this formulation. We introduce a continuous relaxation of the acquisition process that enables pathwise gradients through the full acquisition trajectory, avoiding the high variance of standard score-function policy gradients while allowing end-to-end optimization of a non-myopic acquisition policy. To better align training with deployment, we further develop a straight-through rollout scheme that follows hard feature acquisitions in the forward pass while backpropagating through the corresponding soft relaxation in the backward pass. We stabilize optimization with entropy regularization and staged temperature sharpening. Experiments on both synthetic and real-world datasets demonstrate that NM-PPG yields superior performance relative to state-of-the-art AFA baselines.