Agentic RAG

In agentic search, an LLM agent searches the web, reads the pages it finds, and decides what to look for next before returning an answer. But can we trust an answer simply because the agent returns it? Often not, and even a correct answer can be a lucky guess: on questions with several constraints, we find that agents conclude the task is complete while a constraint remains unverified in up to 48% of their correct answers. We call this illusory completion. To see how it arises, we introduce the Epistemic Ledger, which tracks at every turn what the retrieved pages establish about each constraint and what the agent claims. Across 13 agents, from 7B RL-trained models to frontier LLMs, training and scale raise accuracy but change the pattern of verification failures rather than eliminating them: constraints may be left unchecked, assumed without support, or retained despite refuting evidence. To measure what agents lose without tracking their constraints, we show them each constraint's state, approximated by LiveLedger, a lightweight 4B tracker. Agents then answer 4.4-16.1 points more questions correctly, suggesting that on their own, they may not track what they have verified and what remains.

Writing effective rebuttals is a high-stakes task that demands more than linguistic fluency, as it requires precise alignment between reviewer intent and manuscript details. Current solutions typically treat this as a direct-to-text generation problem, suffering from hallucination, overlooked critiques, and a lack of verifiable grounding. To address these limitations, we introduce $\textbf{RebuttalAgent}$, the first multi-agents framework that reframes rebuttal generation as an evidence-centric planning task. Our system decomposes complex feedback into atomic concerns and dynamically constructs hybrid contexts by synthesizing compressed summaries with high-fidelity text while integrating an autonomous and on-demand external search module to resolve concerns requiring outside literature. By generating an inspectable response plan before drafting, $\textbf{RebuttalAgent}$ ensures that every argument is explicitly anchored in internal or external evidence. We validate our approach on the proposed $\textbf{RebuttalBench}$ and demonstrate that our pipeline outperforms strong baselines in coverage, faithfulness, and strategic coherence, offering a transparent and controllable assistant for the peer review process.

Clinical communication is central to patient outcomes, yet large-scale human annotation of patient-provider conversation remains labor-intensive, inconsistent, and difficult to scale. Existing approaches based on large language models typically rely on single-task models that lack adaptability, interpretability, and reliability, especially when applied across various communication frameworks and clinical domains. In this study, we developed a Multi-framework Structured Agentic AI system for Clinical Communication (MOSAIC), built on a LangGraph-based architecture that orchestrates four core agents, including a Plan Agent for codebook selection and workflow planning, an Update Agent for maintaining up-to-date retrieval databases, a set of Annotation Agents that applies codebook-guided retrieval-augmented generation (RAG) with dynamic few-shot prompting, and a Verification Agent that provides consistency checks and feedback. To evaluate performance, we compared MOSAIC outputs against gold-standard annotations created by trained human coders. We developed and evaluated MOSAIC using 26 gold standard annotated transcripts for training and 50 transcripts for testing, spanning rheumatology and OB/GYN domains. On the test set, MOSAIC achieved an overall F1 score of 0.928. Performance was highest in the Rheumatology subset (F1 = 0.962) and strongest for Patient Behavior (e.g., patients asking questions, expressing preferences, or showing assertiveness). Ablations revealed that MOSAIC outperforms baseline benchmarking.

We present OGD4All, a transparent, auditable, and reproducible framework based on Large Language Models (LLMs) to enhance citizens' interaction with geospatial Open Government Data (OGD). The system combines semantic data retrieval, agentic reasoning for iterative code generation, and secure sandboxed execution that produces verifiable multimodal outputs. Evaluated on a 199-question benchmark covering both factual and unanswerable questions, across 430 City-of-Zurich datasets and 11 LLMs, OGD4All reaches 98% analytical correctness and 94% recall while reliably rejecting questions unsupported by available data, which minimizes hallucination risks. Statistical robustness tests, as well as expert feedback, show reliability and social relevance. The proposed approach shows how LLMs can provide explainable, multimodal access to public data, advancing trustworthy AI for open governance.

Hallucination remains one of the key obstacles to the reliable deployment of large language models (LLMs). Although various mitigation approaches have been proposed, existing studies often analyze different technical paradigms independently, lacking a unified perspective to understand the underlying mechanisms of different approaches and their correspondence with different types of hallucinations. This survey adopts a capability enhancement perspective to systematically examine hallucination mitigation approaches, focusing on Retrieval-Augmented Generation (RAG), reasoning enhancement, and their integration within agentic systems. Based on their primary mitigation mechanisms, we categorize hallucinations into knowledge-based hallucinations and logic-based hallucinations, analyze how RAG and reasoning enhancement methods respectively improve knowledge acquisition and reasoning reliability, and further discuss the integration mechanisms of retrieval and reasoning capabilities in Agentic Systems for mitigating composite hallucinations. By considering the applicability, mitigation mechanisms, and limitations of different approaches, this survey establishes a unified analytical framework connecting hallucination types, key capability dimensions, and technical paradigms.

Recent advances in large language models have demonstrated considerable potential in scientific domains such as drug repositioning. However, their effectiveness remains constrained when reasoning extends beyond the knowledge acquired during pretraining. Conventional approaches, such as fine-tuning or retrieval-augmented generation, face limitations in either imposing high computational overhead or failing to fully exploit structured scientific data. To overcome these challenges, we propose DrugMCTS, a novel framework that synergistically integrates RAG, multi-agent collaboration, and Monte Carlo Tree Search for drug repositioning. The framework employs five specialized agents tasked with retrieving and analyzing molecular and protein information, thereby enabling structured and iterative reasoning. Extensive experiments on the DrugBank and KIBA datasets demonstrate that DrugMCTS achieves substantially higher recall and robustness compared to both general-purpose LLMs and deep learning baselines. Our results highlight the importance of structured reasoning, agent-based collaboration, and feedback-driven search mechanisms in advancing LLM applications for drug repositioning.