Functional Connectivity

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Overview

Functional connectivity studies how activity in different brain regions covaries, helping researchers characterize brain organization and its links to cognition, behavior, and disorders. Common approaches derive connectivity from fMRI or EEG using correlations or synchrony, then analyze static or time-varying networks with graph, higher-order, and geometric methods. Deep learning and multimodal models combine these networks with structural imaging, while self-supervised and foundation models aim to learn representations that transfer across tasks and datasets. A key challenge is ensuring that strong predictions generalize across sites, parcellations, and scan conditions and that identified connections are reproducible and biologically interpretable.

Latest papers

CardsList

60 papers13 papers in the last four weeks, up 117% on the four weeks before. 0.1% of all new papers.

  1. Every route counts, but some count more: a max-plus view of the C. elegans brain

    Oct 27, 2026Emma Reyner-Fuentes, Sebastian Rudolph, Carmen Peláez-Moreno +1Brain Network AnalysisFunctional Connectivity

    Department of Signal Theory and Communications, University Carlos III of Madrid (UC3M), Leganés, Madrid, Spain. · Department of Signal Theory and Communications and Telematic Systems and Computation, University Rey Juan Carlos, Fuenlabrada, Madrid, Spain. · Computational Logic Group, Institute for Artificial Intelligence, Technische Universität Dresden, Dresden, Saxony, Germany.

  2. How Reliable Is Individualized Functional-Network Attribution in Resting-State fMRI Cognitive Prediction in ADNI?

    Oct 27, 2026Sheethal Bhat, Mahfuzur Rahman Chowdhury, Imam Ahmed Shaik +3Feature AttributionExplanation Stability

    Pattern Recognition Lab, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Martensstr. 3, 91058 Erlangen, Germany · Siemens Healthineers, Henkestr. 127, 91052 Erlangen, Germany

  3. MCDA: Multi-View Graph Contrastive Learning with Dynamic Topology Augmentation for Functional MRI Analysis

    Oct 19, 2026Hao Zhang, Xiaoyun Liu, Shuo Huang +4Graph Contrastive LearningFunctional Magnetic Resonance Imaging

    College of Biomedical Engineering, Fudan University, Shanghai 200433, China · College of Information Science and Technology & Artificial Intelligence, Nanjing Forestry University, Nanjing 210037, China · Department of Psychosomatics and Psychiatry, Zhongda Hospital, School of Medicine, Jiangsu Provincial Key Laboratory of Brain Science and Medicine, Southeast University, Nanjing 210009, China +3

  4. MAGNET: Manifold-Aware Graph Diffusion Network for Connectome Generation

    Oct 12, 2026Protyay Dey, Ayush Roy, Hyuna Cho +2Functional ConnectivityNeuroimaging

    University at Buffalo, SUNY, USA · National Institutes of Health, USA · POSTECH, South Korea

  5. CoFlu-Brain: An fMRI Connectivity Foundation Model with Cofluctuation-Based Pretraining

    Oct 11, 2026Ziteng Sui, Junfeng Xia, Wenhao Ye +2fMRI Foundation ModelsfMRI Representation Learning

    Department of Biomedical Engineering, Southern University of Science and Technology, China · School of Biomedical Engineering, Shenzhen University, China · Department of Computer Science, University of Warwick, UK

  6. MovieSTAGE: Scene, Transition, and Global Encoding for Movie-fMRI ADHD Classification

    Oct 7, 2026Boseong Kim, Haejun Chung, Ikbeom JangBrain Disorder ClassificationNeuroimaging

    Hanyang University, Seoul, Republic of Korea · Hankuk University of Foreign Studies, Yongin, Republic of Korea

  7. CoHyFuse: Condition-wise Hypergraph Fusion with Global Connectome in Task-fMRI

    Oct 5, 2026Boseong Kim, Haejun Chung, Ikbeom JangFunctional ConnectivityNeuroimaging

    Hanyang University, Seoul, Republic of Korea · Hankuk University of Foreign Studies, Yongin, Republic of Korea

  8. Structural-Functional Brain Connectivity Generation via Multimodal Hypergraph-based Flow Matching

    Oct 2, 2026Chyong Yi Poh, Hwa Hui Tew, Junn Yong Loo +4Multimodal GenerationFunctional Connectivity

    School of Information Technology, Monash University Malaysia · School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore · Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

  9. BrainNet Studio: A Unified Toolkit for Brain Network Construction, Intelligent Analysis, and Visualization

    Sep 29, 2026Xiwei Zeng, Shengrong Li, Yiheng Liu +3Functional ConnectivityNeuroimaging

    College of Artificial Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China · School of Computer Science and Technology, Harbin Institute of Technology, Harbin, China

  10. GRFBrain: Graph-Structured Rectified Flows for EEG Dynamic Modeling

    Sep 29, 2026Haohui Jia, Zheng Chen, Jathurshan Pradeepkumar +4ElectroencephalographyFunctional Connectivity

    Faculty of Information Science and Technology, Hokkaido University, Japan · SANKEN, The University of Osaka, Japan · Department of Computer Science, University of Illinois Urbana-Champaign, USA +1

  11. Flattening the Connectome Spectrum: A Spectral Filter for FC Induces a Pretraining Target for fMRI Encoders

    Sep 29, 2026Giovanni Marraffini, Victoria Shevchenko, Carlo Alberto Barbano +1Kernel Ridge RegressionMedical Imaging Foundation Models

    UNITO · MIND

  12. High-Resolution Dynamic Functional Connectivity Generation with Graph-Variate Flow Matching

    Sep 29, 2026Om Roy, Yashar Moshfeghi, Keith Malcolm SmithDynamic Functional ConnectivityFunctional Connectivity

    University of Strathclyde

  13. Deep Learning Methods in Neuroscience: From Modeling Molecular Mechanisms to Classifying States of Consciousness

    Sep 28, 2026Elena Benderskaya, Anastasiia Alifanova, Svetlana Batalova +2Functional ConnectivityBrain Network Analysis

    Peter the Great St. Petersburg Polytechnic University, Polytechnicheskaya, 29, 195251 St.Petersburg, Russia

  14. Beyond Site Agreement: Re-estimation for Brain Network Generalization

    Sep 28, 2026Yingxu Wang, Kunyu Zhang, Yanwu Yang3 +4Functional ConnectivityOOD Generalization

    Mohamed bin Zayed University of Artificial Intelligence · Zhengzhou University · University Hospital Tübingen +3

  15. FAST-Brain: A Flow-Aligned Spatio-Temporal Surrogate Brain Model

    Sep 28, 2026Shucheng Liu, Changchun Shi, Kai Zhang +1Neural Surrogate ModelingFunctional Connectivity

    University of North Carolina at Chapel Hill · London School of Economics and Political Science

  16. Explainable Deep Learning of Resting-State Functional Connectomes Reveals Network Biomarkers of Adolescent Intelligence

    Sep 27, 2026Md. Tanvir Rahman, Nabil Anan Orka, Asaduzzaman Khan +1Explainable Artificial IntelligenceFunctional Connectivity

    School of Health and Rehabilitation Sciences, The University of Queensland, QLD 4072, Australia · Department of Information and Communication Technology, Mawlana Bhashani Science and Technology University, Tangail 1902, Bangladesh

  17. Bayesian Uncertainty Quantification for fMRI Functional Connectivity via Simulation-Based Inference

    Sep 24, 2026Simon Carter, Zeming Kuang, Lilianne R. Mujica-Parodi +1Functional Magnetic Resonance ImagingFunctional Connectivity

    Applied Mathematics and Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook NY 11794-5281, USA · Biomedical Engineering Department and Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook NY 11794-5281, USA · Santa Fe Institute, Santa Fe, NM, USA

  18. It's the Geometry, Not the Model: Effective Rank and Subspace Alignment in Functional Connectivity Classification

    Sep 24, 2026Xiao Fan, Jingyuan Li, Yubo Han +6Intrinsic DimensionalityFunctional Connectivity

  19. Artificial Structure Function Search: Preserving Artificial Functional Connectivity for Structured Pruning

    Sep 21, 2026Mindula Illeperuma, Rafael Pina, Charuka Herath +2Model CompressionFunctional Connectivity

    Intitute for Digital Technologies, Loughborough University London · Center for Neuromorphic Intelligence, Aston University

  20. XAI-Refine: An Automated Explanation-Knowledge Loop for Brain-Age Prediction

    Sep 8, 2026Yang Qiao, Junjie Wu, Deqiang Qiu +2Explainable Artificial IntelligenceFunctional Connectivity

    Department of Computer Science Emory University Atlanta, Georgia, USA · Department of Radiology and Imaging Sciences Computational NeuroImaging & Neuroscience Lab, Emory University Atlanta, Georgia, USA · Department of Neurology Emory University School of Medicine Atlanta, Georgia, USA

  21. Benchmarking External Generalization of SPD Matrix Learning for Resting-State fMRI Connectome Prediction

    Aug 31, 2026Ce Ju, Antoine Collas, Florent Bouchard +1Functional ConnectivityBrain Age Prediction

    Inria, CEA, Universit´e Paris-Saclay, Palaiseau, France · Universit´e Paris-Saclay, CNRS, CentraleSup´elec, L2S, France

  22. Multiscale Community-Based Fingerprinting of Signed Functional Networks

    Aug 25, 2026Sema Athamnah, Selin AviyenteBrain Network AnalysisNeuroimaging

    Department of Biomedical Engineering, Michigan State University, USA. · Department of Electrical and Computer Engineering, Michigan State University, USA.

  23. MSR-IVA: Masked Structural Residual Independent Vector Analysis for State-Aware Fusion of Structural MRI and Dynamic Functional Network Connectivity

    Aug 25, 2026Victor Solomon, Zening Fu, Rafal Angryk +2Dynamic Functional ConnectivityMultimodal Fusion

    Department of Computer Science, Georgia State University · Tri-Institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State University, Georgia Institute of Technology, and Emory University

  24. Graph-Based Approaches to Learning Epileptogenic Zone Localization Using Stereo-EEG Recordings

    Aug 19, 2026Daniel Wendelken, Brian Ervin, Ravindra Arya +1Graph Structure LearningBrain Network Analysis

    University of Cincinnati, Cincinnati, USA · Dept. of Computer Science University of Cincinnati Cincinnati, USA · Cincinnati Children's Hospital Medical Center, Cincinnati, USA +2

  25. BrainLinear: A Linear Model for Brain Network Analysis in Sparse Tangent Subspaces

    Aug 15, 2026Sijing Wu, Dongyuan Li, Miaoting Huang +4Brain Network AnalysisFunctional Connectivity

    Guangdong University of Foreign Studies · The University of Tokyo · RIKEN AIP +1

  26. Beyond Local Power: Functional Connectivity Analysis for Subject-Independent Learning Style Recognition

    Aug 12, 2026Wiga Maulana Baihaqi, Indriana Hidayah, Sri Kusrohmaniah +1Cross-Subject EEG DecodingFunctional Connectivity

    Dept. of Electrical and Information Engineering, Faculty of Engineering, Universitas Gadjah Mada, Yogyakarta, Indonesia · Department of Psychology, Faculty of Psychology, Universitas Gadjah Mada, Yogyakarta, Indonesia

  27. FedDOSE: Federated Learning Framework Decomposing Site Effects for Modeling Brain Dynamic Functional Connectivity

    Aug 7, 2026Deepank Girish, Yi Hao Chan, Yubin Zheng +2Tucker DecompositionFunctional Connectivity

    Nanyang Technological University · Shanghai Jiao Tong University · Indian Institute of Technology Ropar

  28. An Attention-Based Framework for Alzheimers Disease Classification Using Resting-State fMRI

    Jul 29, 2026Harshiddhi Pathak, Gowtham Reddy N, Mrinal Acharya +1Alzheimer's DiseaseFunctional Connectivity

    School of Medical Science and Technology · Department of Computer Science and Engineering at the Indian Institute of Technology Gandhinagar · Dr B C Roy Multi Speciality Medical Research Centre, Indian Institute of Technology Kharagpur, India

  29. BrainRiem: Riemannian Prototype Learning for Source-Free Cross-Site Brain Network Diagnosis

    Jun 28, 2026Kunyu Zhang, Tianxiang XuSource-Free Domain AdaptationFunctional Connectivity

    Zhengzhou University, Zhengzhou 450000, China · Peking University, Beijing 102600, China

  30. Sex-based Network-Specific Differences in Connectomes: A Krakencoder-Based Analysis

    Jun 15, 2026Vibhashree S H, Debanjali Bhattacharya, Vamshi Krishna Kancharla +1Functional ConnectivityNeuroimaging

    Centre for Brain Research, Indian Institute of Science, Bengaluru 560012, India · Dept. of Artificial Intelligence, Amrita School of Artificial Intelligence, Amrita Vishwa Vidyapeetham, Bengaluru 560035, India