Hypothesis-Driven Model Expansion

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4 papers in the last four weeks, against 2 the four weeks before. 0.0% of all new papers.

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  1. From Scientific Observations to Mechanisms: Benchmarking Hypothesis Generation by AI Scientists

    Oct 4, 2026Xiaxun Xie, Qingqing Long, Meng Xiao +4Artificial Intelligence ScientistsHypothesis-Driven Model Expansion

    Computer Network Information Center, Chinese Academy of Sciences · National University of Singapore · Sichuan University

  2. PEAR: Progressive Evidence-Based AutoResearch for Industrial Search Systems

    Sep 28, 2026Yifan Wang, Shipeng Zhu, Fei Xiong +6Research AutomationAgentic Optimization

    Global E-Commerce Agentic Search Team

  3. HypoEvolve: Genetic Algorithms Enable Multi-Agent LLMs to Discover Scientific Hypotheses

    Sep 14, 2026Jieyuan Liu, Mengzhou Hu, Jefferson Chen +10Hypothesis-Driven Model ExpansionMulti-Agent Evolution

    University of California San Diego · 2Texas A&M University · 3Carnegie Mellon University +1

  4. HypoKG: Evidence-Disciplined Biomedical Hypothesis Generation Beyond Endpoint Knowledge

    Sep 14, 2026Dominic Okonkwo, Adetayo Okunoye, Ismailcem Budak ArpinarBiomedical Knowledge GraphHypothesis-Driven Model Expansion

    School of Computing University of Georgia

  5. HyGRAIL: Cost-Aware and Evidence-Grounded Scientific Hypothesis Discovery over Knowledge Graphs

    Sep 2, 2026Yihang Sun, Zhihan Zhu, Zhiyuan Jiang +3Knowledge GraphsHypothesis-Driven Model Expansion

    University of Illinois Urbana-Champaign

  6. Generative artificial intelligence for reliable mechanistic reasoning for corrosion

    Aug 31, 2026Bharath M N, R K Singh Raman, Alankar AlankarData-Driven Materials DiscoveryHypothesis-Driven Model Expansion

    Department of Mechanical Engineering, Indian Institute of Technology Bombay, Mumbai, Maharashtra, 400076, India · Department of Mechanical and Aerospace Engineering, Monash University, Clayton 3800, Victoria, Australia · IITB-Monash Research Academy, Mumbai, Maharashtra, 400076, India +1

  7. Abduction Without a Body? Representational Grounding and the Abduction Loop for Scientific Hypothesis Generation

    Aug 3, 2026Michael FarmerAbductive ReasoningHypothesis-Driven Model Expansion

    August 2026 (v1.18)

  8. (EC)2: Event-Centric Explainability for Cybersecurity Through Multi-Agent LLM Investigations

    Jul 28, 2026Neta Kirmayer, David Tayouri, Andrés Murillo +3CybersecurityInterpretable Anomaly Detection

    Ben-Gurion University of the Negev, Beer-Sheva, Israel · Fujitsu

  9. Before the Action: Benchmarking LLMs on Prospective Hypothesis Discovery

    Jul 17, 2026Tianyun Zhong, Wangyi Jiang, Wei Wang +15Hypothesis-Driven Model ExpansionHypothesis

    University of Chinese Academy of Sciences · Institute of Software, Chinese Academy of Sciences · 3Alibaba Group

  10. LLM-PDESR: Robust PDE Discovery via Subdomain Weighted Residuals and LLM-Guided Symbolic Hypothesis Generation

    Jul 12, 2026Jinyang Du, Hao Ma, Xiaohu Shi +4Symbolic RegressionSurrogate Models

    College of Computer Science and Technology, Jilin University, Changchun, China · School of Big Data and Artificial Intelligence, Guangdong University of Finance and Economics, Guangzhou, China · Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education, Jilin University, Changchun, China +2

  11. Toward Auditable AI Scientists: A Hypothesis Evolution Protocol for LLM Agents

    Jul 10, 2026Izumi Takahara, Teruyasu MizoguchiArtificial Intelligence ScientistsHypothesis-Driven Model Expansion

    Institute of Industrial Science, The University of Tokyo, Tokyo, Japan 153-8505

  12. XALPHA: A Memory-Driven AI Quant Researcher for Hypothesis-to-Code Alpha Discovery

    Jul 9, 2026Fengyuan Liu, Yuchen Fu, Yuqi Wang +1Algorithmic TradingHypothesis-Driven Model Expansion

    School of Computing and Data Science, The University of Hong Kong · Grace Investment Machine

  13. Hypothesis-driven Model Expansion under Uncertainty for Open-World Robot Planning

    Jul 7, 2026Anxing Xiao, Hanbo Zhang, Tianrun Hu +1Robot PlanningWorld Model Planning

    School of Computing, National University of Singapore · Smart Systems Institute, National University of Singapore

  14. EO-Agents: A Three-Agent LLM Pipeline for Earth Observation Hypothesis Generation

    Jul 2, 2026Mahyar Ghazanfari, Amin Tabrizian, Armin Mehrabian +1Hypothesis-Driven Model ExpansionEarth Observation

    George Washington University, Washington, DC, USA · NASA Goddard Space Flight Center, Greenbelt, MD, USA · ADNET Systems, Inc., Bethesda, MD, USA

  15. Graph-Native Reinforcement Learning Enables Traceable Scientific Hypothesis Generation through Conceptual Recombination

    Jul 1, 2026Subhadeep Pal, Shashwat Sourav, Tirthankar Ghosal +1Reasoning GraphsHypothesis-Driven Model Expansion

    Department of Civil and Environmental Engineering MASSACHUSETTS INSTITUTE OF TECHNOLOGY Cambridge, MA, USA · Department of Physics Washington University in St. Louis St. Louis, MO, USA · Computing and Computational Sciences Directorate Oak Ridge National Laboratory Oak Ridge, TN, USA +3

  16. Toward Generalist Autonomous Research via Hypothesis-Tree Refinement

    Jun 10, 2026Jiajie Jin, Yuyang Hu, Kai Qiu +15Research AutomationHypothesis-Driven Model Expansion

    Gaoling School of Artificial Intelligence, Renmin University of China · Microsoft Research

  17. Towards Diverse Scientific Hypothesis Search with Large Language Models

    Jun 9, 2026Haorui Wang, Parshin Shojaee, Kazem Meidani +7Hypothesis-Driven Model ExpansionHypothesis

    Georgia Institute of Technology · Virginia Tech · Carnegie Mellon University +3

  18. DN-Hypo-Pipeline: An AI-Driven Workflow for Generating Hypotheses using Large Language Models and Scientific Explanations

    Jun 7, 2026Lei Lin, Ronghao Wang, Chunbao Zhou +2Hypothesis-Driven Model ExpansionScientific Discovery

    Computer Network Information Center, Chinese Academy of Sciences, China

  19. FALSIFYBENCH: Evaluating Inductive Reasoning in LLMs with Rule Discovery Games

    Jun 3, 2026Leonardo Bertolazzi, Katya Tentori, Raffaella BernardiHypothesis-Driven Model ExpansionScientific Discovery

    University of Trento · Free University of Bozen-Bolzano

  20. HypoAgent: An Agentic Framework for Interactive Abductive Hypothesis Generation over Knowledge Graphs

    May 29, 2026Yisen Gao, Yixi Cai, Tianshi Zheng +2Hypothesis-Driven Model ExpansionAgentic Reasoning

    The Hong Kong University of Science and Technology · Beihang University · 3Hong Kong Baptist University

  21. Agora: Toward Autonomous Bug Detection in Production-Level Consensus Protocols with LLM Agents

    May 28, 2026Xiang Liu, Sa Song, Zhaowei Zhang +6Bug DetectionSmart Contracts

    School of Computing, National University of Singapore · School of Information and Telecommunication Engineering, Beijing University of Posts and Telecommunications · Peking University +1

  22. MOOSE-Copilot: A Web-Based Interactive Assistant for Unified Exploratory and Fine-Grained Scientific Hypothesis Discovery

    May 28, 2026Hongran An, Zonglin YangHypothesis-Driven Model ExpansionScientific Discovery

    Central Conservatory of Music · Nanyang Technological University

  23. The Compressive Knowledge Graph Hypothesis: Which Graph Facts Matter for Scientific Hypothesis Generation?

    May 26, 2026Shashwat Sourav, Viktoriia Baibakova, Sanjay Das +4Knowledge GraphsHypothesis-Driven Model Expansion

    1Washington University in St. Louis · 2Oak Ridge National Laboratory · 3Lawrence Berkeley National Laboratory +1

  24. Hypothesis-driven construction of mesoscopic dynamics

    May 15, 2026Zhuoyuan Li, Aiqing Zhu, Qianxiao LiHypothesis-Driven Model ExpansionConstruction

    Institute for Functional Intelligent Materials, National University of Singapore · Department of Mathematics, National University of Singapore

  25. Hypothesis-Driven Deep Research with Large Language Models: A Structured Methodology for Automated Knowledge Discovery

    May 11, 2026Michael ChinHypothesis-Driven Model ExpansionScientific Discovery

    Independent Researcher

  26. Agentic AI Scientists Are Not Built For Autonomous Scientific Discovery

    May 9, 2026Harshit Bisht, Vinay Kumar, Kevin Maik Jablonka +2Artificial Intelligence ScientistsScientific Agents

    Yardi School of Artificial Intelligence, Indian Institute of Technology Delhi · Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena · Center for Energy and Environmental Chemistry Jena, Friedrich Schiller University Jena +3

  27. Human-LLM Dialogue Improves Diagnostic Accuracy in Emergency Care

    May 8, 2026Burcu Sayin, Ngoc Vo Hong, Ipek Baris Schlicht +8Clinical Reasoning TrainingEmergency Departments

    Department of Information Engineering and Computer Science, University of Trento, Italy · Department of Medicine, Azienda Sanitaria Universitaria Integrata del Trentino (ASUIT), Trento, Italy · Universitat Politècnica de València, Spain +2

  28. LLM-Guided Open Hypothesis Learning from Autonomous Scanning Probe Microscopy Experiments

    May 7, 2026Boris Slautin, Utkarsh Pratiush, Yu Liu +2Hypothesis-Driven Model ExpansionData-Driven Materials Discovery

    Department of Materials Science and Engineering, University of Tennessee, Knoxville, TN 37923, USA

  29. An explainable hypothesis-driven approach to Drug-Induced Liver Injury with HADES

    May 4, 2026Maciej Wisniewski, Bartosz Topolski, Pawel Dabrowski-Tumanski +2Absorption, Distribution, Metabolism, And ExcretionCholangiocarcinoma

    Ingenix.ai, Warsaw, Poland · Laboratory of Bioinformatics and Computational Genomics, Warsaw University of Technology, Warsaw, Poland · Laboratory of Functional and Structural Genomics, Centre of New Technologies, University of Warsaw, Warsaw, Poland

  30. Separable Pathways for Causal Reasoning: How Architectural Scaffolding Enables Hypothesis-Space Restructuring in LLM Agents

    Apr 21, 2026John Alderete, Sebastian Benthal, Connie Xu +1Agentic ReasoningHypothesis-Driven Model Expansion

    Amigo AI · Simon Fraser University · International Computer Science Institute

  31. Continuous Knowledge Metabolism: Generating Scientific Hypotheses from Evolving Literature

    Apr 14, 2026Jinkai Tao, Yubo Wang, Xiaoyu Liu +1Hypothesis-Driven Model ExpansionScientific Discovery

    TsingyuAI, Beijing, China · School of Information, Central University of Finance and Economics, Beijing, China · Thrust of Artificial Intelligence, The Hong Kong University of Science and Technology (Guangzhou), Guangzhou, China +1

  32. From Literature to Hypotheses: An AI Co-Scientist System for Biomarker-Guided Drug Combination Hypothesis Generation

    Feb 28, 2026Raneen Younis, Suvinava Basak, Lukas Chavez +1Hypothesis-Driven Model ExpansionDrug-Drug Interactions

    Peter L. Reichertz Institute for Medical Informatics (PLRI), Hannover Medical School · Lower Saxony Center for Artificial Intelligence and Causal Methods in Medicine (CAIMed) · Sanford Burnham Prebys (SBP) Medical Discovery Institute