Longitudinal Patient Records

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7 papers in the last four weeks, against 1 the four weeks before. 0.1% of all new papers.

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Latest papers 33

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A rubric landscape for evaluating clinical reasoning in large language models: what exists, what is missing, and what needs to be combined
Oct 1, 2026Zhangshu Joshua Jiang, Zina Ibrahim, James T. TeoClinical Reasoning Training LLM Reasoning Strategies
DRIVE-Health CDT Department of Biostatistics and Health Informatics Institute of Psychiatry, Psychology and Neuroscience King’s College London London, UK
Evaluating Biomedical Reranking for LLM-Based Question Answering over Longitudinal Clinical Notes
Oct 1, 2026Maryam Shahbaz Ali, Laura B. Strachan, Caitlin Sherman +3Biomedical Text Reranking
Children’s National Hospital, Washington, DC, USA · University of Florida, Gainesville, FL, USA · George Washington University, Washington DC, USA
Can LLMs Reason Over Long Horizons? An Empirical Evaluation of Context Strategies for Longitudinal Clinical Reasoning
Sep 30, 2026Taye Akinrele, Noorbakhsh Amiri Golilarz, Subash Neupane +2LLM Reasoning Strategies Efficient Long-Context Inference
Department of Computer Science, The University of Alabama
Personalized State-Transition-Aware Memory for Clinical Agents
Sep 29, 2026Maryam Haghifam, Zahra Rajabi, Yizhou Sun +1Longitudinal Patient Records History
Department of Computer Science, University of California, Los Angeles, CA, USA · Optum AI, UnitedHealth Group, Minneapolis, MN, USA
DoAtlas-2: A Foundation for Self-Evolving Causal Biomedical Discovery
Sep 28, 2026Yulong Li, Rong Xia, Yuxuan Zhang +12Causal Discovery Methods Discovery
MBZUAI
Clinical Trajectory Alignment for Medical Vision-Language Pre-training
Sep 28, 2026Huimin Yan, Xian Yang, Zhi Wang +1Medical Vision-Language Models Longitudinal Imaging
Institute of Intelligent Information Processing, Shanxi University, Taiyuan, China · Alliance Manchester Business School, The University of Manchester, Manchester, UK
NOAH: Learning the Full Patient Journey. A Longitudinal Multimodal Time-Aware Model for Representation and Forecasting
Sep 8, 2026Tobias Susetzky, Raphael Rehms, Dmitrii Seletkov +5Patient Trajectories Multimodal Clinical Data
Chair for AI in Healthcare and Medicine, TUM University Hospital and Technical University of Munich (TUM), Munich, Germany · Institute for Diagnostic and Interventional Radiology, TUM University Hospital, Munich, Germany · Munich Center for Machine Learning (MCML), Munich, Germany +3
Review Before Trust: Source-Grounded Integrity Gates for AI-Assisted Personal Health Records
Aug 30, 2026Nora Girda, Adrian GrozaElectronic Health Records Trustworthy Artificial Intelligence
Technical University of Cluj-Napoca, Cluj-Napoca, Romania
ALTER: Modeling Longitudinal Changes via Regional Differencing for 3D CT Report Generation
Aug 6, 2026Dongchen Li, Jitao Liang, Wei LiRadiology Report Generation Cone-Beam Computed Tomography
College of Computer Science and Engineering, Northeastern University, Shenyang, China · National Frontiers Science Center for Industrial Intelligence and Systems Optimization, Shenyang, China · Key Laboratory of Intelligent Computing in Medical Image (MIIC), Northeastern University, Shenyang, China
INCLAIR: Inception-Based Longitudinal Clinical Anomaly Detection with Informed Reasoning
Jul 29, 2026Maxx Richard Rahman, Wolfgang MaassLogical Anomalies Longitudinal Patient Records
German Research Center for Artificial Intelligence (DFKI), Germany · Saarland University, Germany
ClinLens: Towards Long-Horizon Coding Agents for Longitudinal Multimodal Clinical Data Science
Jul 28, 2026Yuan Zhu, Ethan B. Liu, Frank Nie +1Multimodal Clinical Data Longitudinal Patient Records
Shandong University, China
Contrastive Representation Learning of Longitudinal Disease Trajectories on Temporal Graphs
Jul 28, 2026Bastian PfeiferPatient Trajectories Longitudinal Patient Records
Institute for Medical Informatics, Statistics and Documentation · Medical University Graz · Graz, Austria
Color Fundus Photography Analysis: Co-evolution of Data, Preprocessing, and Modeling toward Multimodal AI
Jul 27, 2026Yu Li, Wengan He, Wenhui Xu +7Fundus Images Multimodal Clinical Data
aZhuhai College of Science and Technology, Zhuhai, Guangdong, China · bZhuhai UNO technology Co., Ltd., Zhuhai, Guangdong, China
A Self-Evolving Agent for Longitudinal Personal Health Management
Jul 15, 2026Haoran Li, Jiebi Deng, Tong Jin +10Longitudinal Patient Records Self-Evolving Agents
School of Data Science, Fudan University, Shanghai, China · School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China · Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China +4
LongMedBench: Benchmarking Medical Agents for Long-Horizon Clinical Decision-Making
Jul 10, 2026Zihan Xu, Yanzhen Chen, Xiaocheng Zhang +4Clinical Reasoning Training Longitudinal Patient Records
Zhejiang University, Hangzhou, China · Alibaba Group, Hangzhou, China · Transvascular Implantation Devices Research Institute, Hangzhou, China
The Verbose Context Problem in Medical Records
Jun 28, 2026Shiva Kaul, Min-Gyu Kim, Anjum Khurshid +1Longitudinal Patient Records Question-Answering Benchmarks
Department of Population Medicine · Department of Biomedical Informatics, Ajou University School of Medicine · Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School +1
Transition-Aware best-of-N sampling for Longitudinal Chest X-ray Reports
Jun 23, 2026Halil Ibrahim Gulluk, Max Van Puyvelde, Wim Van Criekinge +1Chest X-Ray Radiology Report Generation
Department of Electrical Engineering, Stanford University, Stanford, CA, USA · Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, CA, USA · Department of Mathematical Modelling, Statistics & Bioinformatics, Ghent University, Ghent, Belgium
Better Adherence, Richer Context: A Field Evaluation of LLM-Powered Conversational Voice Diaries for Sleep
Jun 17, 2026Amama Mahmood, Bokyung Kim, Honghao Zhao +4Sleep Context-Sensitive Daily Routines
The Johns Hopkins University, USA · Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, USA
Bayesian Inference and Decision Audits for Public Archives of Frontier AI Evaluations
Jun 15, 2026Yanan LongArtificial Intelligence Evaluation Model Auditing
StickFlux Labs
A Longitudinal Attribute-Conditioned Neural Network for Modeling Health-State Transition Probabilities in Temporally Irregular Data: The LANTERN Framework
Jun 11, 2026Bright Kwaku Manu, Beckett Sterner, Petar JevticLongitudinal Patient Records Actuarial Ratemaking
School of Computing and Augmented Intelligence, Arizona State University, Tempe, USA · School of Life Sciences, Arizona State University, Tempe, USA · School of Mathematical and Statistical Sciences, Arizona State University, Tempe, USA
A Machine Learning-Based Framework for Discovering Huntington's Disease Stages: Integrating Graph Representation Learning and clustering to Uncover Progression Dynamics in Longitudinal Enroll-HD Dataset
Jun 4, 2026Lubna M. Abu Zohair, Marta Vallejo, MD Azher Uddin +2Disease Longitudinal Patient Records
School of Mathematical and Computer Sciences, Heriot-Watt University, Dubai, United Arab Emirates · School of Mathematical and Computer Sciences, Heriot-Watt University, Edinburgh, United Kingdom
A Unified Benchmark for Dynamic Medical Treatment Reinforcement Learning
May 31, 2026Yuepeng Wang, Ken Kawano, Yoshihiko Fujisawa +12Treatment Skillgym
Tokyo University of Agriculture and Technology · Institute of Science Tokyo · National University of Singapore +5
VitalAgent: A Tool-Augmented Agent for Reactive and Proactive Physiological Monitoring over Wearable Health Data
May 28, 2026Di Zhu, Yu Yvonne Wu, Hong Jia +3Wearable Physiology Wearable Devices
The University of Melbourne, Australia · Dartmouth College, US · University of Auckland, New Zealand +1
Privacy-Preserving Local Language Models for Longitudinal Data Retrieval in Chronic Dermatologic Disease: Implementation in Pemphigus Patients
May 24, 2026Abdurrahim Yilmaz, Ayşe Esra Koku Aksu, Duygu Yamen +5Longitudinal Patient Records Summarization
Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London · Department of Dermatology and Venereology, Istanbul Research and Training Hospital · Department of Dermatology and Venereology, Istanbul Medeniyet University +1
Optimizing Digital Therapeutic Interventions: Online Learning under Endogenous Adherence
May 22, 2026Eric Pulick, Stephanie Carpenter, Matthew Buman +1Clinical Decision Support Sequential Decision Making
Department of Industrial and Systems Engineering, University of Wisconsin-Madison · College of Health Solutions, Arizona State University
ChronoMedKG: A Temporally-Grounded Biomedical Knowledge Graph and Benchmark for Clinical Reasoning
May 21, 2026Md Shamim Ahmed, Farzaneh Firoozbakht, Lukas Galke Poech +2Biomedical Knowledge Graph Clinical Reasoning Training
University of Southern Denmark · University of Hamburg
A Formative Study of Brief Affective Text as a Complement to Wearable Sensing for Longitudinal Student Health Monitoring
May 14, 2026Tamunotonye Harry, Johanna Hidalgo, Matthew Price +7Wearable Physiology Affective Computing
University of Vermont, USA · University of Vermont, USA2026 MIKAELA IRENE FUDOLIG · Adelaide University, Australia +1
EHR-RAGp: Prototype-Guided Retrieval of Longitudinal Electronic Health Records for Clinical Prediction Models
May 12, 2026Saeed Shurrab, Mariam Al-Omari, Dana El Samad +1Medical World Model Electronic Health Records
New York University · New York University Abu Dhabi
PerCaM-Health: Personalized Dynamic Causal Graphs for Healthcare Reasoning
May 8, 2026Elahe Khatibi, Ziyu Wang, Saba A. Farahani +4Causal Discovery Methods Longitudinal Patient Records
University of California, Irvine · Washington University in St. Louis
Detecting Clinical Discrepancies in Health Coaching Agents: A Dual-Stream Memory and Reconciliation Architecture
Apr 29, 2026Samuel L Pugh, Eric Yang, Alexander Muir Sutherland +1Longitudinal Patient Records Long-Term Agent Memory
Verily Health Inc.
Agentic clinical reasoning over longitudinal myeloma records: a retrospective evaluation against expert consensus
Apr 27, 2026Johannes Moll, Jannik Lübberstedt, Christoph Nuernbergk +21Clinical Reasoning Training Longitudinal Patient Records
Chair for AI in Healthcare and Medicine, Technical University of Munich (TUM) and TUM University Hospital, Munich, Germany · Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, TUM University Hospital, School of Medicine and Health, Technical University of Munich, Munich, Germany · Department of Cardiovascular Radiology and Nuclear Medicine, German Heart Center, TUM University Hospital, School of Medicine and Health, Technical University of Munich, Munich, Germany +11
RePrompT: Recurrent Prompt Tuning for Integrating Structured EHR Encoders with Large Language Models
Apr 20, 2026Arya Hadizadeh Moghaddam, Drew Ross, Mohsen Nayebi Kerdabadi +2Electronic Health Records Longitudinal Patient Records
University of Kansas, USA
SafeImpute: Reliable Clinical Data Imputation via Conformal Selection
Date pendingXinrui He, Mengting Ai, Junting Wang +2Imputation Mimic-Iv Datasets
University of Illinois Urbana-Champaign Champaign, IL, USA · Mayo Clinic Scottsdale, AZ, USA

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A rubric landscape for evaluating clinical reasoning in large language models: what exists, what is missing, and what needs to be combined

Zhangshu Joshua Jiang, Zina Ibrahim, James T. Teo

DRIVE-Health CDT Department of Biostatistics and Health Informatics Institute of Psychiatry, Psychology and Neuroscience King’s College London London, UK

Clinical Reasoning Training LLM Reasoning Strategies Large Language Model Benchmarks Longitudinal Patient Records Validation

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Exam-style accuracy does not establish whether large language models (LLMs) reason well over clinical records. We define clinical reasoning as integrating and updating evidence across time and sources to form, revise and justify a patient's problem representation and a defensible plan. This structured narrative review maps three literatures: medical education assessment instruments, clinical LLM benchmarks published from 2023 onwards, and general-domain methods for evaluating long-form generation. We examine six dimensions: problem representation, temporal synthesis, differential and management reasoning, counterfactual reasoning, calibrated uncertainty, and reasoning faithfulness. Preprints are included and flagged. No single instrument covers all six dimensions. Problem representation and differential or management reasoning are reasonably covered, although reliability varies by instrument and setting. TIMER-Eval targets temporal synthesis, and ER-Reason assesses sequential diagnostic belief updating. Dedicated uncertainty and counterfactual evaluations are emerging, but their applicability to longitudinal free-text reasoning remains limited. Factual completeness is well theorised in general-domain evaluation, with early clinical evidence of important omissions. Faithfulness remains the weakest dimension, with one identified clinical causal-ablation study on multiple-choice questions. Existing tools should be combined through binary rubric items, separate completeness and correctness scores, case-specific importance weighting with non-compensable safety caps, temporal order-consistency checks, and chance-corrected reliability reporting. Further design work is needed for calibrated uncertainty, counterfactual reasoning and faithfulness over longitudinal free-text records. This review provides a design rationale, not a validated instrument.

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