Medical Imaging Foundation Models

Overview

Medical imaging foundation models aim to learn reusable features from large collections of images, scans, and sometimes paired clinical reports, then apply them to tasks such as diagnosis, segmentation, measurement, and report generation. Common approaches include self-supervised learning, masked-image prediction, vision-language contrastive learning, and generative models, with both 2D and volumetric methods for modalities such as radiology, MRI, ultrasound, pathology, and retinal imaging. Researchers adapt these models through fine-tuning, lightweight adapters such as LoRA, frozen-feature probes, or prompts, and assess them on classification, segmentation, and cross-center benchmarks. A central tension is whether broad pretraining reliably helps specific clinical tasks: results vary by modality and task, and robustness to shifts in scanners, populations, and institutions remains essential to establish before deployment.

Latest papers

CardsList

235 papers21 papers in the last four weeks, down 28% on the four weeks before. 0.1% of all new papers.

  1. EchoPilot: Training-Free Ultrasound Video Segmentation via Scale-Space Semantic Prompting and Reliability-Gated Memory

    May 25, 2026Ruiqiang Xiao, Zhaohu Xing, Yijun Yang +4Interactive Medical Image SegmentationImage Segmentation

  2. Universal CT Representations from Anatomy to Disease Phenotype through Agglomerative Pretraining

    May 21, 2026Yuheng Li, Yuan Gao, Haoyu Dong +5Medical Imaging Foundation ModelsMedical VLMs

  3. Learning Emergent Modular Representations in Multi-modality Medical Vision Foundation Models

    May 21, 2026Yuting He, Chenyu You, Shuo LiMedical Imaging Foundation ModelsMultimodal Pretraining

  4. An Open Multi-Center Whole-Body FDG PET/CT Foundation Model for Tumor Segmentation

    May 20, 2026Xiaofeng Liu, Qianru Zhang, Thibault Marin +4Cross-Modality Medical Image SegmentationMedical Imaging Foundation Models

  5. VoxCor: Training-Free Volumetric Features for Multimodal Voxel Correspondence

    May 13, 2026Guney Tombak, Ertunc Erdil, Ender KonukogluMedical Imaging Foundation ModelsCross-Modal Representation Learning

  6. MedCore: Boundary-Preserving Medical Core Pruning for MedSAM

    May 13, 2026Cenwei Zhang, Suncheng Xiang, Lei YouModel CompressionImage Segmentation

  7. MultiMedVision: Multi-Modal Medical Vision Framework

    May 9, 2026Frank Li, Bardia Khosravi, Mohammadreza Chavoshi +5Medical Imaging Foundation ModelsVision Transformer

  8. Benchmarking Foundation Models for Renal Lesion Stratification in CT

    May 8, 2026Hartmut Häntze, Sarah de Boer, Myrthe Buser +7Medical Imaging Foundation ModelsMedical Image Classification

  9. DINO-MVR: Multi-View Readout of Frozen DINOv3 for Annotation-Efficient Medical Segmentation

    May 8, 2026Wei Jiang, Feng Liu, Nan Ye +1Image SegmentationMedical Imaging Foundation Models

  10. Pan-FM: A Pan-Organ Foundation Model with Saliency-Guided Masking for Missing Robustness

    May 8, 2026Qiangqiang Wu, Grace McIlvain, Zhou Yu +1Missing-Modality LearningMedical Imaging

  11. Knowledge Transfer Scaling Laws for 3D Medical Imaging

    May 7, 2026Ho Hin Lee, Dongna Du, Chu Wang +4Medical Imaging Foundation Models3D Medical Imaging

  12. Deep Reprogramming Distillation for Medical Foundation Models

    May 6, 2026Siyuan Du, Yuhang Zhou, Haolin Li +5Medical Imaging Foundation ModelsVision Foundation Model Adaptation

  13. OphMAE: Bridging Volumetric and Planar Imaging with a Foundation Model for Adaptive Ophthalmological Diagnosis

    May 4, 2026Tienyu Chang, Zhen Chen, Renjie Liang +9Medical Imaging Foundation ModelsMasked Autoencoders

  14. Representation learning from OCT images

    May 4, 2026Hedi Tabia, Désiré Sidibé, Nawres Khlifa +6Medical ImagingMedical Imaging Foundation Models

  15. GeoSAE: Geometric Prior-Guided Layer-Wise Sparse Autoencoder Annotation of Brain MRI Foundation Models

    May 3, 2026Favour Nerrise, Lucy Yin, Mohammad H. Abbasi +2Alzheimer's DiseaseMedical Imaging Foundation Models

  16. BrainDINO: A Brain MRI Foundation Model for Generalizable Clinical Representation Learning

    Apr 30, 2026Yizhou Wu, Shansong Wang, Yuheng Li +5Medical Imaging Foundation ModelsSelf-Supervised Pre-Training

  17. DiffuSAM: Diffusion-Based Prompt-Free SAM2 for Few-Shot and Source-Free Medical Image Segmentation

    Apr 27, 2026Tal Grossman, Noa Cahan, Lev Ayzenberg +1Diffusion ModelsImage Segmentation

  18. EXACT: an explainable anomaly-aware vision foundation model for analysis of 3D chest CT

    Apr 27, 2026Xuguang Bai, Mingxuan Liu, Tongxi Song +6Medical Imaging Foundation ModelsRadiology VLMs

  19. SemiSAM-O1: How far can we push the boundary of annotation-efficient medical image segmentation?

    Apr 27, 2026Yichi Zhang, Le Xue, Bichun Xu +6Image SegmentationMedical Imaging Foundation Models

  20. Learning from Noisy Prompts: Saliency-Guided Prompt Distillation for Robust Segmentation with SAM

    Apr 25, 2026Jingxuan Kang, Ziqi Zhang, Shaoming Zheng +9Medical Imaging Foundation ModelsPromptable Image Segmentation

  21. Foundation models for discovering robust biomarkers of neurological disorders from dynamic functional connectivity

    Apr 23, 2026Deepank Girish, Yi Hao Chan, Sukrit Gupta +2Medical Imaging Foundation ModelsFunctional Connectivity

  22. SegTTA: Training-Free Test-Time Augmentation for Zero-Shot Medical Imaging Segmentation

    Apr 19, 2026Yihong Yao, Chunlei Li, Canxuan Gang +4Image SegmentationMedical Imaging Foundation Models

  23. SGP-SAM: Self-Gated Prompting for Transferring 3D Segment Anything Models to Lesion Segmentation

    Apr 19, 2026Zequan Yao, Zixuan Tang, Jielin Ma +1Image SegmentationMedical Imaging Foundation Models

  24. Unified Ultrasound Intelligence Toward an End-to-End Agentic System

    Apr 18, 2026Chen Ma, Yunshu Li, Junhu Fu +3Medical Imaging Foundation ModelsMulti-Task Learning

  25. Beyond Independent Frames: Latent Attention Masked Autoencoders for Multi-View Echocardiography

    Apr 16, 2026Simon Böhi, Irene Cannistraci, Sergio Muñoz Gonzalez +8Medical Imaging Foundation ModelsMasked Autoencoders

  26. Brain-DiT: A Universal Multi-state fMRI Foundation Model with Metadata-Conditioned Pretraining

    Apr 14, 2026Junfeng Xia, Wenhao Ye, Xuanye Pan +3Medical Imaging Foundation ModelsDiffusion Transformer

  27. Seeing Through the Tool: A Controlled Benchmark for Occlusion Robustness in Foundation Segmentation Models

    Apr 13, 2026Nhan Ho, Luu Le, Thanh-Huy Nguyen +3Amodal SegmentationImage Segmentation