Quantum-Inspired ML

Node embeddings act as the information interface for graph neural networks, yet their empirical impact is often reported under mismatched backbones, splits, and training budgets. This paper provides a controlled benchmark of embedding choices for graph classification, comparing classical baselines with quantum-oriented node representations under a unified pipeline. We evaluate two classical baselines alongside quantum-oriented alternatives, including a circuit-defined variational embedding and quantum-inspired embeddings computed via graph operators and linear-algebraic constructions. All variants are trained and tested with the same backbone, stratified splits, identical optimization and early stopping, and consistent metrics. Experiments on five different TU datasets and on QM9 converted to classification via target binning show clear dataset dependence: quantum-oriented embeddings yield the most consistent gains on structure-driven benchmarks, while social graphs with limited node attributes remain well served by classical baselines. The study highlights practical trade-offs between inductive bias, trainability, and stability under a fixed training budget, and offers a reproducible reference point for selecting quantum-oriented embeddings in graph learning.

Tensor networks were developed in the context of many-body physics as compressed representations of multiparticle quantum states. These representations mitigate the exponential complexity of many-body systems by capturing only the most relevant dependencies. Due to the formal similarity between quantum entanglement and statistical correlations, tensor networks have recently been integrated in machine learning, operating both as alternative learning architectures and as decompositions of components of neural networks. The expectation is that the theoretical understanding of tensor networks developed within quantum many-body physics leads to novel methods that offer advantages in terms of computational efficiency, explainability, or privacy. Here we review the use of tensor networks in the context of machine learning, providing a critical assessment of the state of the art, the potential advantages, and the challenges that must be overcome.

Text embeddings are central to modern information retrieval and Retrieval-Augmented Generation (RAG). While dense models derived from Large Language Models (LLMs) dominate current practice, recent work has explored quantum-inspired alternatives motivated by the geometric properties of Hilbert-like spaces and their potential to encode richer semantic structure. This paper presents an experimental framework for constructing quantum-inspired 1024-dimensional document embeddings based on overlapping windows and multi-scale aggregation. The pipeline combines semantic projections (e.g., EigAngle), circuit-inspired feature mappings, and optional teacher-student distillation, together with a fingerprinting mechanism for reproducibility and controlled evaluation. We introduce a set of diagnostic tools for hybrid retrieval, including static and dynamic interpolation between BM25 and embedding-based scores, candidate union strategies, and a conceptual alpha-oracle that provides an upper bound for score-level fusion. Experiments on controlled corpora of Italian and English documents across technical, narrative, and legal domains, using synthetic queries, show that BM25 remains a strong baseline, teacher embeddings provide stable semantic structure, and standalone quantum-inspired embeddings exhibit weak and unstable ranking signals. Distillation yields mixed effects, improving alignment in some cases but not consistently enhancing retrieval performance, while hybrid retrieval can recover competitive results when lexical and embedding-based signals are combined. Overall, the results highlight structural limitations in the geometry of quantum-inspired embeddings, including distance compression and ranking instability, and clarify their role as auxiliary components rather than standalone retrieval representations.

We propose Quantum Vision (QV) theory as a new perspective for deep learning-based audio classification, applied to deepfake speech detection. Inspired by particle-wave duality in quantum physics, QV theory is based on the idea that data can be represented not only in its observable, collapsed form, but also as information waves. In conventional deep learning, models are trained directly on these collapsed representations, such as images. In QV theory, inputs are first transformed into information waves using a QV block, and then fed into deep learning models for classification. QV-based models improve performance in image classification compared to their non-QV counterparts. What if QV theory is applied speech spectrograms for audio classification tasks? This is the motivation and novelty of the proposed approach. In this work, Short-Time Fourier Transform (STFT), Mel-spectrograms, and Mel-Frequency Cepstral Coefficients (MFCC) of speech signals are converted into information waves using the proposed QV block and used to train QV-based Convolutional Neural Networks (QV-CNN) and QV-based Vision Transformers (QV-ViT). Extensive experiments are conducted on the ASVSpoof dataset for deepfake speech classification. The results show that QV-CNN and QV-ViT consistently outperform standard CNN and ViT models, achieving higher classification accuracy and improved robustness in distinguishing genuine and spoofed speech. Moreover, the QV-CNN model using MFCC features achieves the best overall performance on the ASVspoof dataset, with an accuracy of 94.20% and an EER of 9.04%, while the QV-CNN with Mel-spectrograms attains the highest accuracy of 94.57%. These findings demonstrate that QV theory is an effective and promising approach for audio deepfake detection and opens new directions for quantum-inspired learning in audio perception tasks.

Quantum-inspired tensor networks algorithms have shown to be effective and efficient models for machine learning tasks, including anomaly detection. Here, we propose a highly parallelizable quantum-inspired approach which we call SMT-AD from Superposition of Multiresolution Tensors for Anomaly Detection. It is based upon the superposition of bond-dimension-1 matrix product operators to transform the input data with Fourier-assisted feature embedding, where the number of learnable parameters grows linearly with feature size, embedding resolutions, and the number of additional components in the matrix product operators structure. We demonstrate successful anomaly detection when applied to standard datasets, including credit card transactions, and find that, even with minimal configurations, it achieves competitive performance against established anomaly detection baselines. Furthermore, it provides a straightforward way to reduce the weight of the model and even improve the performance by highlighting the most relevant input features.

Experiments probing natural language processing by both humans and LLMs suggest that the meaning of a semantic expression is indeterminate prior to the act of interpretation rather than being specifiable simply as the sum of its parts (i.e. compositionality). This observer-dependent act dynamically actualizes meaning under genuine contextuality more consistent with quantum logical mechanisms than with classical Boolean approaches that assume separability, motivating an approach to language modeling that utilizes a Hilbert space formalism. In this work, we introduce Phase-Associative Memory (PAM) -- a complex-valued sequence model whose state S_t \in \mathbb{C}^{d \times d} accumulates outer products of complex token embeddings retrieved through the conjugate inner product $\mathrm{Re}\langle K \mid Q\rangle / \sqrt{d}$ -- and evaluate it against a structurally matched real-valued ablation. Both architectures train stably across a 5M--100M parameter sweep on WikiText-103 under identical conditions; PAM sits at higher absolute loss at every measured scale but improves more rapidly with parameter count, with power-law exponents of $-0.15$ vs.\ $-0.12$ in loss and $-0.65$ vs.\ $-0.49$ in perplexity that narrow the gap between the two architectures monotonically. Further investigation of complex-valued sequence modeling at larger scales could reveal that the loss plateau characteristic of real-valued state-of-the-art language models (e.g. transformers) is reachable with PAM-style architectures with an order of magnitude fewer parameters than the current frontier ($\sim$1T), implying that similar capabilities are achievable at sizes runnable on consumer-grade hardware.

Quantum machine learning offers the ability to capture complex correlations in high-dimensional feature spaces, crucial for the challenge of detecting beyond the Standard Model physics in collider events, along with the potential for unprecedented computational efficiency in future quantum processors. Near-term utilization of these benefits can be achieved by developing quantum-inspired algorithms for deployment in classical hardware to enable applications at the "edge" of current scientific experiments. This work demonstrates the use of tensor networks for real-time anomaly detection in collider detectors. A spaced matrix product operator (SMPO) is developed that provides sensitivity to a variety beyond the Standard Model benchmarks, and can be implemented in field programmable gate array hardware with resources and latency consistent with trigger deployment. The cascaded SMPO architecture is introduced as an SMPO variation that affords greater flexibility and efficiency in ways that are key to edge applications in resource-constrained environments. These results reveal the benefit and near-term feasibility of deploying quantum-inspired ML in high energy colliders.

Driver heterogeneity is often reduced to labels or discrete regimes, compressing what is inherently dynamic into static categories. We introduce quantum-inspired representation that models each driver as an evolving latent state, presented as a density matrix with structured mathematical properties. Behavioral observations are embedded via non-linear Random Fourier Features, while state evolution blends temporal persistence of behavior with context-dependent profile activation. We evaluate our approach on empirical driving data, Third Generation Simulation Data (TGSIM), showing how driving profiles are extracted and analyzed.

We present PhasorFlow, an open-source Python library for computing on the $S^1$ unit circle. Inputs are encoded as complex phasors $z=e^{iφ}$ on the $N$-torus ($\mathbb{T}^N$); as computation proceeds through unitary wave-interference gates, global norm is preserved while components drift into $\mathbb{C}^N$, letting algorithms leverage continuous geometric gradients. PhasorFlow makes three contributions. First, we formalize the Phasor Circuit model ($N$ threads, $M$ gates) with a 22-gate library spanning standard-unitary, non-linear, neuromorphic, and encoding operations under full matrix-algebra simulation. Second, we introduce the Variational Phasor Circuit (VPC), a trainable phase-native classifier analogous to variational quantum circuits. Third, we introduce the Phasor Transformer block and Large Phasor Model (LPM), replacing $QK^TV$ attention with a parameter-free DFT token-mixing layer. We validate the framework on financial volatility detection, neuromorphic associative memory, neural binding, period finding, and algorithmic logic applications that are unique to the library. This positions unit-circle computing as a deterministic, lightweight paradigm on classical hardware. Available at https://github.com/mindverse-computing/phasorflow.

Accurate prediction of residue-level pKa values is essential for understanding protein function, stability, and reactivity. While existing resources such as DeepKaDB and CpHMD-derived datasets provide valuable training data, their descriptors remain primarily classical and often struggle to generalize across diverse biochemical environments. We introduce a reproducible hybrid quantum-classical framework that enriches residue-level representations with a Gaussian kernel-based quantum-inspired feature mapping. These quantum-enhanced descriptors are combined with normalized structural features to form a unified hybrid encoding processed by a Deep Quantum Neural Network (DQNN). This architecture captures nonlinear relationships in residue microenvironments that are not accessible to classical models. Benchmarking across multiple curated descriptor sets demonstrates that the DQNN achieves improved cross-context generalization relative to classical baselines. External evaluation on the PKAD-R experimental benchmark and an A$β$40 case study further highlights the robustness and transferability of the quantum-inspired representation. By integrating quantum-inspired feature transformations with classical biochemical descriptors, this work establishes a scalable and experimentally transferable approach for residue-level pKa prediction and broader applications in protein electrostatics.

Recent studies show that quantum neural networks (QNNs) generalize well in few-shot regimes. To extend this advantage to large-scale tasks, we propose Q-LoRA, a quantum-enhanced fine-tuning scheme that integrates lightweight QNNs into the low-rank adaptation (LoRA) adapter. Applied to AI-generated content (AIGC) detection, Q-LoRA consistently outperforms standard LoRA under few-shot settings. We analyze the source of this improvement and identify two possible structural inductive biases from QNNs: (i) phase-aware representations, which encode richer information across orthogonal amplitude-phase components, and (ii) norm-constrained transformations, which stabilize optimization via inherent orthogonality. However, Q-LoRA incurs non-trivial overhead due to quantum simulation. Motivated by our analysis, we further introduce H-LoRA, a fully classical variant that applies the Hilbert transform within the LoRA adapter to retain similar phase structure and constraints. Experiments on few-shot AIGC detection show that both Q-LoRA and H-LoRA outperform standard LoRA by over 5% accuracy, with H-LoRA achieving comparable accuracy at significantly lower cost in this task.

We investigate a quantum-inspired approach to supervised multi-class classification based on the Pretty Good Measurement (PGM), viewed as an operator-valued decision rule derived from quantum state discrimination. The method associates each class with an encoded mixed state and performs classification through a single POVM construction, thus providing a genuinely multi-class strategy without reduction to pairwise or one-vs-rest schemes. In this perspective, classification is reformulated as the discrimination of a finite ensemble of class-dependent density operators, with performance governed by the geometry induced by the encoding map and by the overlap structure among classes. To assess the practical scope of this framework, we apply the PGM-based classifier to two biomedical radiomics case studies: histopathological subtyping of non-small-cell lung carcinoma (NSCLC) and prostate cancer (PCa) risk stratification. The evaluation is conducted under protocols aligned with previously reported radiomics studies, enabling direct comparison with established classical baselines. The results show that the PGM-based classifier is consistently competitive and, in several settings, improves upon standard methods. In particular, the method performs especially well in the NSCLC binary and three-class tasks, while remaining competitive in the four-class case, where increased class overlap yields a more demanding discrimination geometry. In the PCa study, the PGM classifier remains close to the strongest ensemble baseline and exhibits clinically relevant sensitivity--specificity trade-offs across feature-selection scenarios.

Quantum deep learning (QDL) explores the use of both quantum and quantum-inspired resources to determine when deep learning's core capabilities, such as expressivity, generalization, and scalability, can be enhanced based on specific resource constraints. Distinct from broader quantum machine learning, QDL emphasizes compositional depth at the pipeline level and the integration of quantum or quantum-inspired components within end-to-end workflows. This review provides an operational definition of QDL and introduces a taxonomy comprising four primary paradigms: hybrid quantum-classical models, quantum deep neural networks, quantum algorithms for deep learning primitives, and quantum-inspired classical algorithms. Theoretical principles are connected to advanced architectures, software toolchains, and experimental demonstrations across superconducting, trapped-ion, photonic, semiconductor spin, and neutral-atom systems, as well as quantum annealers. Claims of quantum advantage are critically assessed by distinguishing provable complexity-theoretic separations from empirical observations. The analysis characterizes trade-offs between model expressivity, trainability, and classical simulability, while systematically detailing the bottlenecks imposed by optimization landscapes, input-output access models, and hardware constraints. Applications are surveyed in domains encompassing image classification, natural language processing, scientific discovery, quantum data processing, and quantum optimal control, underscoring fair benchmarking against optimized classical counterparts and a comprehensive assessment of resource requirements. This review serves as a tutorial entry point for graduate students while guiding readers to specialized literature. It concludes with a verification-aware roadmap to transition QDL from near-term demonstrations to scalable and fault-tolerant implementations.

We introduce a sequence modeling framework in which the latent state is a complex-valued wave function evolving on a finite-dimensional Hilbert space under a learned, time-dependent Hamiltonian. Unlike standard recurrent architectures that rely on gating mechanisms to suppress competing hypotheses, our framework utilizes quantum interference: the Hamiltonian steers the phases of complex amplitudes so that conflicting interpretations cancel while compatible ones reinforce. The dynamics are strictly unitary, ensuring that the state norm is preserved exactly at every time step via a Cayley (Crank--Nicolson) discretization. Token probabilities are extracted using the Born rule, a quadratic measurement operator that couples magnitudes and relative phases. Our primary theoretical contribution is a separation theorem characterizing the representational advantage of this readout: we define a family of disambiguation tasks that a complex unitary model of dimension $N$ solves exactly, but which requires a state dimension of $Ω(N^2)$ for any real-valued orthogonal model equipped with a standard affine-softmax readout. This quadratic gap arises because the Born rule implicitly lifts the $N$-dimensional state into the space of rank-one Hermitian matrices, accessing pairwise phase correlations that are inaccessible to linear projections. Finally, we derive a continuity equation for the latent probability mass, yielding conserved pairwise currents that serve as a built-in diagnostic for tracing information flow between dimensions.

In this paper, a learning framework is introduced which incorporates principles of probabilistic inference, variational optimization, and geometry-preserving operations inspired by quantum transformations. The central innovation of this quantum-inspired variational convolution (QiVC) lies in its quantum-inspired rotated ensemble (QiRE) mechanism. QiRE performs differentiable low-dimensional subspace rotations of convolutional weights. By drawing a mathematical analogy from unitary evolution, this approach enables structured uncertainty modeling that respects the intrinsic geometry of the parameter space. To demonstrate its practical potential, the concept is instantiated in a QiVC-based convolutional network (QiVC-Net) and evaluated in the context of biosignal classification, focusing on phonocardiogram (PCG) recordings. The proposed QiVC-Net integrates an architecture in which the QiVC layer does not introduce additional parameters, instead performing an ensemble rotation of the convolutional weights through a structured mechanism ensuring robustness without added highly computational burden. Experiments on two benchmark datasets, PhysioNet CinC 2016 and PhysioNet CirCor DigiScope 2022, show that QiVC-Net achieves state-of-the-art performance, reaching accuracies of 97.84% and 97.89%, respectively. These findings highlight the versatility of the QiVC framework and its promise for advancing uncertainty-aware modeling in real-world biomedical signal analysis. The implementation of the QiVConv layer is available in GitHub for public use.

Variational quantum circuits (VQCs) are central to quantum machine learning, while recent progress in Kolmogorov-Arnold networks (KANs) highlights the power of learnable activation functions. We unify these directions by introducing the quantum variational activation function (QVAF), a general framework in which parameterized quantum circuits serve as learnable activation functions; in this work we study an efficient single-qubit instantiation called DatA Re-Uploading ActivatioN (DARUAN). We show that DARUAN with trainable data-preprocessing weights can realize an exponentially growing accessible frequency support with the number of re-uploading repetitions; for an explicit geometric choice of these weights, this gives a capacity-level exponential parameter reduction relative to independently parameterized Fourier activations. Embedding DARUAN into KAN yields the quantum-inspired Kolmogorov-Arnold Network (QKAN), which retains the interpretability of the KAN architecture while improving parameter efficiency, expressivity, and generalization. We further introduce layer extension and the hybrid QKAN (HQKAN) architecture to improve scalability and computational efficiency, enabling QKAN modules to act as compact replacements for multi-layer perceptrons (MLPs) in large-scale models. We provide theoretical analysis and extensive experiments on function regression, image classification, and autoregressive generative language modeling, demonstrating the efficiency and scalability of QKANs. Because the single-qubit circuits are efficiently simulable on classical quantum simulators, QKANs have quantum-inspired advantage in parameter efficiency and training stability; DARUANs and QKANs serve as present-day validation of the QVAF concept, and the trained DARUANs are directly executable and feasible on current noisy intermediate-scale quantum (NISQ) hardware for inference validation.

Data imputation is a critical preprocessing step, particularly in clinical datasets where missingness can bias downstream inference. We propose a quantum-inspired imputation framework and evaluate it on the UCI Pima Indians Diabetes dataset, where several physiological variables contain structural zeros that are treated as missing. The approach combines Principal Component Analysis (PCA) with quantum rotation-based reconstruction, where rotation angles are selected via gradient-free optimizers (Simulated Annealing, COBYLA, and Differential Evolution). For robustness, we retain the top three optimizer solutions per method and reconstruct missing values under distribution-aware bounds (e.g., $\pm 2$ standard deviations) and avoid unrealistic collapse toward central tendency. We also benchmark against (i) classical baselines (Mean, KNN, MICE, Decision Tree), (ii) modern matrix/ML imputers (SoftImpute, MissForest, VAE), and (iii) rotation/PCA controls (random orthogonal rotations and bootstrap PCA). Across the evaluated features, quantum-inspired variants achieve substantially improved distributional fidelity under Wasserstein W1 relative to modern baselines (e.g., the best quantum setting reduces average W1 by $\sim$66% vs. SoftImpute, $\sim$84% vs. MissForest, and $\sim$90% vs. VAE; and by $\sim$60% vs. Mean imputation), while remaining competitive with strong classical/control configurations. Dispersion is better preserved under the quantum-inspired methods, with variance/SD ratios closer to the observed data than (SoftImpute, MissForest, and VAE) and typically better than (Mean, KNN, MICE, and Decision Tree) on average. Overall, the results support quantum-inspired, optimization-guided rotations as a statistically grounded and scalable strategy for realistic imputation in healthcare and general AI pipelines, with a design that can be mapped to future quantum hardware as it matures.